| Mitochondrial dysfunction caused by outer membrane vesicles from Gram-negative bacteria activates intrinsic apoptosis and inflammation P Deo, SH Chow, ML Han, M Speir, C Huang, RB Schittenhelm, S Dhital, ... Nature microbiology 5 (11), 1418-1427, 2020 | 163 | 2020 |
| A synthetic lipopeptide targeting top-priority multidrug-resistant Gram-negative pathogens KD Roberts, Y Zhu, MAK Azad, ML Han, J Wang, L Wang, HH Yu, ... Nature Communications 13 (1), 1625, 2022 | 100 | 2022 |
| Fitness cost of mcr-1-mediated polymyxin resistance in Klebsiella pneumoniae SC Nang, FC Morris, MJ McDonald, ML Han, J Wang, RA Strugnell, ... Journal of Antimicrobial Chemotherapy 73 (6), 1604-1610, 2018 | 89 | 2018 |
| An “unlikely” pair: the antimicrobial synergy of polymyxin B in combination with the cystic fibrosis transmembrane conductance regulator drugs KALYDECO and ORKAMBI EK Schneider, MAK Azad, ML Han, Q Zhou, J Wang, JX Huang, ... ACS infectious diseases 2 (7), 478-488, 2016 | 85 | 2016 |
| Eurifoloids A–R, Structurally Diverse Diterpenoids from Euphorbia neriifolia JX Zhao, CP Liu, WY Qi, ML Han, YS Han, MA Wainberg, JM Yue Journal of Natural Products 77 (10), 2224-2233, 2014 | 84 | 2014 |
| Structure, function, and biosynthetic origin of octapeptin antibiotics active against extensively drug-resistant Gram-negative bacteria T Velkov, A Gallardo-Godoy, JD Swarbrick, MAT Blaskovich, AG Elliott, ... Cell chemical biology 25 (4), 380-391. e5, 2018 | 74 | 2018 |
| Comparative metabolomics and transcriptomics reveal multiple pathways associated with polymyxin killing in Pseudomonas aeruginosa ML Han, Y Zhu, DJ Creek, YW Lin, AD Gutu, P Hertzog, T Purcell, ... MSystems 4 (1), 10.1128/msystems. 00149-18, 2019 | 68 | 2019 |
| Emergence of high-level colistin resistance in an Acinetobacter baumannii clinical isolate mediated by inactivation of the global regulator H-NS D Deveson Lucas, B Crane, A Wright, ML Han, J Moffatt, D Bulach, ... Antimicrobial Agents and Chemotherapy 62 (7), 10.1128/aac. 02442-17, 2018 | 65 | 2018 |
| Alterations of metabolic and lipid profiles in polymyxin-resistant Pseudomonas aeruginosa ML Han, Y Zhu, DJ Creek, YW Lin, D Anderson, HH Shen, B Tsuji, ... Antimicrobial agents and chemotherapy 62 (6), 10.1128/aac. 02656-17, 2018 | 63 | 2018 |
| Polymyxin-Induced Lipid A Deacylation in Pseudomonas aeruginosa Perturbs Polymyxin Penetration and Confers High-Level Resistance ML Han, T Velkov, Y Zhu, KD Roberts, AP Le Brun, SH Chow, AD Gutu, ... ACS chemical biology 13 (1), 121-130, 2018 | 61 | 2018 |
| Genome-scale metabolic modeling of responses to polymyxins in Pseudomonas aeruginosa Y Zhu, T Czauderna, J Zhao, M Klapperstueck, MHM Maifiah, ML Han, ... GigaScience 7 (4), giy021, 2018 | 59 | 2018 |
| Polymyxins Bind to the Cell Surface of Unculturable Acinetobacter baumannii and Cause Unique Dependent Resistance Y Zhu, J Lu, ML Han, X Jiang, MAK Azad, NA Patil, YW Lin, J Zhao, Y Hu, ... Advanced Science 7 (15), 2000704, 2020 | 56 | 2020 |
| From breast cancer to antimicrobial: combating extremely resistant Gram-negative “superbugs” using novel combinations of polymyxin B with selective estrogen receptor modulators MH Hussein, EK Schneider, AG Elliott, M Han, F Reyes-Ortega, F Morris, ... Microbial Drug Resistance 23 (5), 640-650, 2017 | 55 | 2017 |
| Global metabolic analyses identify key differences in metabolite levels between polymyxin-susceptible and polymyxin-resistant Acinetobacter baumannii MH Mahamad Maifiah, SE Cheah, MD Johnson, ML Han, JD Boyce, ... Scientific Reports 6 (1), 22287, 2016 | 55 | 2016 |
| Walsucochinoids A and B: New Rearranged Limonoids from Walsura cochinchinensis ML Han, H Zhang, SP Yang, JM Yue Organic letters 14 (2), 486-489, 2012 | 52 | 2012 |
| A polytherapy based approach to combat antimicrobial resistance using cubosomes X Lai, ML Han, Y Ding, SH Chow, AP Le Brun, CM Wu, PJ Bergen, J Jiang, ... Nature Communications 13 (1), 343, 2022 | 51 | 2022 |
| Trigoxyphins A−G: Diterpenes from Trigonostemon xyphophylloides BD Lin, ML Han, YC Ji, HD Chen, SP Yang, S Zhang, MY Geng, JM Yue Journal of natural products 73 (7), 1301-1305, 2010 | 51 | 2010 |
| Pharmacokinetics/pharmacodynamics of antipseudomonal bacteriophage therapy in rats: a proof-of-concept study YW Lin, RY Chang, GG Rao, B Jermain, ML Han, JX Zhao, K Chen, ... Clinical Microbiology and Infection 26 (9), 1229-1235, 2020 | 47 | 2020 |
| Comparative metabolomics reveals key pathways associated with the synergistic killing of colistin and sulbactam combination against multidrug-resistant Acinetobacter baumannii ML Han, X Liu, T Velkov, YW Lin, Y Zhu, DJ Creek, CK Barlow, HH Yu, ... Frontiers in Pharmacology 10, 754, 2019 | 45 | 2019 |
| Metabolomics study of the synergistic killing of polymyxin B in combination with amikacin against polymyxin-susceptible and-resistant Pseudomonas aeruginosa M Hussein, ML Han, Y Zhu, Q Zhou, YW Lin, REW Hancock, D Hoyer, ... Antimicrobial Agents and Chemotherapy 64 (1), 10.1128/aac. 01587-19, 2019 | 44 | 2019 |
