Structural modeling of ion channels using AlphaFold2, RoseTTAFold2, and ESMFold PT Nguyen, BJ Harris, DL Mateos, AH González, AM Murray, ... Channels 18 (1), 2325032, 2024 | 13 | 2024 |
The H3K4me1 histone mark recruits DNA repair to functionally constrained genomic regions in plants D Quiroz, D Lopez-Mateos, K Zhao, A Pierce, L Ortega, A Ali, ... bioRxiv, 2022.05. 28.493846, 2022 | 13 | 2022 |
H3K4me1 recruits DNA repair proteins in plants D Quiroz, S Oya, D Lopez-Mateos, K Zhao, A Pierce, L Ortega, A Ali, ... The Plant Cell 36 (6), 2410-2426, 2024 | 10 | 2024 |
Structural and Functional Characterization of a Novel Scorpion Toxin that Inhibits NaV1.8 via Interactions With the DI Voltage Sensor and DII Pore Module K George, D Lopez-Mateos, TM Abd El-Aziz, Y Xiao, J Kline, H Bao, ... Frontiers in Pharmacology 13, 846992, 2022 | 7 | 2022 |
Elucidating molecular mechanisms of protoxin-II state-specific binding to the human NaV1. 7 channel K Ngo, D Lopez Mateos, Y Han, KC Rouen, SH Ahn, H Wulff, CE Clancy, ... Journal of General Physiology 156 (2), 2024 | 6 | 2024 |
Structural modeling of peptide toxin–ion channel interactions using RosettaDock DL Mateos, V Yarov‐Yarovoy Proteins: Structure, Function, and Bioinformatics 91 (7), 872-889, 2023 | 4 | 2023 |
Electrostatic screening, acidic pH and macromolecular crowding increase the self-assembly efficiency of the minute virus of mice capsid in vitro MA Fuertes, D López Mateos, L Valiente, A Rodríguez Huete, A Valbuena, ... Viruses 15 (5), 1054, 2023 | 2 | 2023 |
Harnessing deep learning methods for voltage-gated ion channel drug discovery D Lopez-Mateos, BJ Harris, A Hernández-González, K Narang, ... Physiology 40 (1), 67-87, 2025 | 1 | 2025 |
Atomistic mechanisms of the regulation of small-conductance Ca2+-activated K+ channel (SK2) by PIP2 RL Woltz, Y Zheng, W Choi, K Ngo, P Trinh, L Ren, PN Thai, BJ Harris, ... Proceedings of the National Academy of Sciences 121 (39), e2318900121, 2024 | 1 | 2024 |
Harnessing Deep Learning Methods for Voltage-Gated Ion Channel Drug Discovery DL Mateos, BJ Harris, AH González, K Narang, V Yarov-Yarovoy Physiology, 2024 | 1 | 2024 |
Computationally driven design of novel BACE-1 inhibitors for Alzheimer’s disease MM Chinn, DL Mateos, MA Riley, JB Siegel bioRxiv, 2023.11. 15.567308, 2023 | 1 | 2023 |
Computational design of peptides stabilizing Nav1. 7 channel in an inactivated state DL Mateos, AH Gonzalez, V Yarov-Yarovoy Biophysical Journal 122 (3), 102a, 2023 | 1 | 2023 |
BPS2025-Exploring voltage-gated sodium channel conformations and interactions using AlphaFold DL Mateos, K Narang, V Yarov-Yarovoy Biophysical Journal 124 (3), 121a, 2025 | | 2025 |
BPS2025-Disruption of a R395: E398 salt bridge by PIP2 shifts the state distribution toward an open and conductive state in human small-conductance Ca2+-activated K+ channels RL Woltz, Y Zheng, W Choi, K Ngo, P Trinh, L Ren, P Thai, BJ Harris, ... Biophysical Journal 124 (3), 127a-128a, 2025 | | 2025 |
BPS2025-Computational design of NaV1. 8 sodium channel inhibitors as novel non-addictive treatments for pain management K Narang, DL Mateos, A Murray, V Yarov-Yarovoy Biophysical Journal 124 (3), 539a, 2025 | | 2025 |
Exploring voltage-gated sodium channel conformations and protein-protein interactions using AlphaFold2 D Lopez-Mateos, K Narang, V Yarov-Yarovoy bioRxiv, 2024 | | 2024 |
Computational design of binders targeting the VSDIV from NaV1. 7 sodium channel DL Mateos, AM Murray, HM Nguyen, P Venkatesh, B Koepnick, D Baker, ... Biophysical Journal 123 (3), 108a, 2024 | | 2024 |
MD simulation identifies a novel and direct mechanism for PIP2 activation of SK2 RL Woltz, W Choi, K Ngo, BJ Harris, Y Han, K Rouen, P Trinh, ... Biophysical Journal 123 (3), 256a, 2024 | | 2024 |
De Novo Protein Design of Potent and Selective Modulators of Voltage-Gated Sodium Channels for Treatment of Pain DL Mateos University of California, Davis, 2024 | | 2024 |
De Novo Protein Design of Potent and Selective Modulators of Voltage-Gated Sodium Channels for Treatment of Pain D Lopez Mateos UC Davis, 2024 | | 2024 |