Regulatory T cells shield muscle mitochondria from interferon-γ–mediated damage to promote the beneficial effects of exercise PK Langston, Y Sun, BA Ryback, AL Mueller, BM Spiegelman, C Benoist, ... Science immunology 8 (89), eadi5377, 2023 | 38 | 2023 |
Metabolic adaptation to vitamin auxotrophy by leaf-associated bacteria B Ryback, M Bortfeld-Miller, JA Vorholt The ISME Journal 16 (12), 2712-2724, 2022 | 36 | 2022 |
A Model of the Spatio-temporal Dynamics of Drosophila Eye Disc Development P Fried, M Sánchez-Aragón, D Aguilar-Hidalgo, B Lehtinen, F Casares, ... PLoS computational biology 12 (9), e1005052, 2016 | 36 | 2016 |
Strong FGFR3 staining is a marker for FGFR3 fusions in diffuse gliomas KJ Granberg, M Annala, B Lehtinen, J Kesseli, J Haapasalo, ... Neuro-oncology 19 (9), 1206-1216, 2017 | 34 | 2017 |
Dynamic character displacement among a pair of bacterial phyllosphere commensals in situ L Hemmerle, BA Maier, M Bortfeld-Miller, B Ryback, CG Gäbelein, ... Nature Communications 13 (1), 2836, 2022 | 25 | 2022 |
Clinical association analysis of ependymomas and pilocytic astrocytomas reveals elevated FGFR3 and FGFR1 expression in aggressive ependymomas B Lehtinen, A Raita, J Kesseli, M Annala, K Nordfors, O Yli-Harja, ... Bmc Cancer 17, 1-12, 2017 | 25 | 2017 |
A High‐Throughput Workflow for CRISPR/Cas9 Mediated Combinatorial Promoter Replacements and Phenotype Characterization in Yeast J Kuivanen, S Holmström, B Lehtinen, M Penttilä, J Jäntti Biotechnology Journal 13 (9), 1700593, 2018 | 13 | 2018 |
Moderate-to-strong expression of FGFR3 and TP53 alterations in a subpopulation of choroid plexus tumors KJ Granberg, A Raita, B Lehtinen, AM Tiihonen, J Kesseli, M Annala, ... Universidad de Murcia, Departamento de Biologia Celular e Histiologia, 2020 | 3 | 2020 |
TFE3 fusions direct an oncogenic transcriptional program that drives OXPHOS and unveils vulnerabilities in translocation renal cell carcinoma J Li, K Huang, F McBride, A Sadagopan, DS Gallant, M Thakur, P Khanna, ... bioRxiv, 2024 | 2 | 2024 |
Coenzyme biosynthesis in response to precursor availability reveals incorporation of β-alanine from pantothenate in prototrophic bacteria B Ryback, JA Vorholt Journal of Biological Chemistry 299 (8), 2023 | 2 | 2023 |
Mitochondrial membrane potential regulates nuclear DNA methylation and gene expression through phospholipid remodeling MP Mori, O Lozoya, AM Brooks, D Grenet, CA Nadalutti, B Ryback, ... BioRxiv, 2024 | 1 | 2024 |
Ergothioneine controls mitochondrial function and exercise performance via direct activation of MPST HG Sprenger, MJ Mittenbühler, Y Sun, JG Van Vranken, S Schindler, ... Cell Metabolism, 2025 | | 2025 |
Oncogenic TFE3 fusions drive OXPHOS and confer metabolic vulnerabilities in translocation renal cell carcinoma J Li, K Huang, M Thakur, F McBride, A Sadagopan, DS Gallant, P Khanna, ... Nature Metabolism, 1-15, 2025 | | 2025 |
Riboflavin Drives Nucleotide Biosynthesis and Iron-Sulfur Metabolism to Promote Acute Myeloid Leukemia S Bjelosevic, R Fauth, BT Do, G Alexe, B Ryback, AT Basanthakumar, ... Blood 144, 626, 2024 | | 2024 |
Loss of Negative Metabolic Feedback Drives TET2 Mutant Inflammation GG Kim, CB Hergott, AP Miller, A Deik, M Boileau, K Bullock, K Pierce, ... Blood 144, 4060, 2024 | | 2024 |
Renalase inhibition regulates β cell metabolism to defend against acute and chronic stress T MacDonald, B Ryback, JA da Silva Pereira, S Wei, B Mendez, E Cai, ... bioRxiv, 2024.06. 11.598322, 2024 | | 2024 |
Ergothioneine boosts mitochondrial respiration and exercise performance via direct activation of MPST HG Sprenger, MJ Mittenbühler, Y Sun, JG Van Vranken, S Schindler, ... bioRxiv, 2024.04. 10.588849, 2024 | | 2024 |
Genomic and environmental determinants of bacterial coenzyme metabolism BAA Ryback ETH Zurich, 2021 | | 2021 |
Strong FGFR3 staining is a marker for FGFR3 fusions and poor prognosis in diffuse gliomas KJ Granberg, M Annala, B Lehtinen, J Kesseli, J Haapasalo, O Yli-Harja, ... Cancer Research 76 (14_Supplement), 5011-5011, 2016 | | 2016 |
A pipeline to optimize metabolic pathways in the synthetically regulated Saccharomyces cerevisiae using tryptophan pathway as an example B Lehtinen | | 2016 |