Structural alterations driving castration-resistant prostate cancer revealed by linked-read genome sequencing SR Viswanathan, G Ha, AM Hoff, JA Wala, J Carrot-Zhang, CW Whelan, ... Cell 174 (2), 433-447. e19, 2018 | 359 | 2018 |
Single-cell genomic profiling of human dopamine neurons identifies a population that selectively degenerates in Parkinson’s disease T Kamath*, A Abdulraouf*, SJ Burris, J Langlieb, V Gazestani, NM Nadaf, ... Nature Neuroscience, 1-8, 2022 | 313 | 2022 |
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain SE Marsh, AJ Walker, T Kamath, L Dissing-Olesen, TR Hammond, ... Nature Neuroscience 25 (3), 306-316, 2022 | 290 | 2022 |
Early Alzheimer’s disease pathology in human cortex involves transient cell states V Gazestani*, T Kamath*, NM Nadaf, A Dougalis, SJ Burris, B Rooney, ... Cell 186 (20), 4438-4453. e23, 2023 | 93 | 2023 |
Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro MJ Dolan, M Therrien, S Jereb, T Kamath, V Gazestani, T Atkeson, ... Nature Immunology, 1-9, 2023 | 80* | 2023 |
Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin JS Wang, T Kamath, CM Mazur, F Mirzamohammadi, D Rotter, H Hojo, ... Nature Communications 12 (1), 6271, 2021 | 74 | 2021 |
A Size‐Selective Intracellular Delivery Platform MT Saung, A Sharei, VA Adalsteinsson, N Cho, T Kamath, C Ruiz, ... Small 12 (42), 5873-5881, 2016 | 35 | 2016 |
Schizophrenia-associated somatic copy-number variants from 12,834 cases reveal recurrent NRXN1 and ABCB11 disruptions EA Maury, MA Sherman, G Genovese, TG Gilgenast, T Kamath, SJ Burris, ... Cell Genomics 3 (8), 2023 | 18 | 2023 |
Mutator/hypermutable fetal/juvenile metakaryotic stem cells and human colorectal carcinogenesis LG Kini, P Herrero-Jimenez, EE Furth, T Kamath, J Sanghvi, E Gutierrez Jr, ... Frontiers in oncology 3, 267, 2013 | 9 | 2013 |
Metakaryotic cancer stem cells are constitutively resistant to X-rays and chemotherapeutic agents, but sensitive to many common drugs EV Gostjeva, VV Koledova, L Bai, KC Duan, T Kamath, M Nelson, ... | 7 | 2016 |
Insights into Neurodegeneration in Parkinson's Disease from Single‐Cell and Spatial Genomics T Kamath, EZ Macosko Movement Disorders 38 (4), 518-525, 2023 | 3 | 2023 |
Improved heritability partitioning and enrichment analyses using summary statistics with graphREML H Li, T Kamath, R Mazumder, X Lin, L O'Connor medRxiv, 2024.11. 04.24316716, 2024 | | 2024 |
A toolkit to study microglia states using stem cell‐derived models M Therrien, MJ Dolan, S Jereb, T Kamath, D Meyer, T Atkeson, CK Glass, ... Alzheimer's & Dementia 19, e080796, 2023 | | 2023 |
Single-cell genomic profiling of human dopaminergic neurons identifies a population selectively vulnerable in Parkinson's disease T Kamath Alzheimer's Association International Conference, 2023 | | 2023 |
Molecular and cellular responses to amyloid beta revealed from single cell analysis of surgical brain biopsies T Kamath, V Gazestani, MJ Dolan, N Nadaf, C Vanderburg, V Leinonen, ... Alzheimer's & Dementia 18, e062241, 2022 | | 2022 |
Multi‐modal Analysis and Modeling of Human Neurodegenerative Disease to Reveal Disease Mechanisms and Biomarkers SE Marsh, S Murphy, T Kamath, V Gazestani, M Therrien, MJ Dolan, ... Alzheimer's & Dementia 18, e061905, 2022 | | 2022 |
Cell states and neuronal vulnerabilities in neurodegenerative diseases TV Kamath Harvard University, 2022 | | 2022 |
Single Cell Sequencing Reveals Glial Specific Responses to Tissue Processing & Post-Mortem Across Species SE Marsh, T Kamath, AJ Walker, L Dissing-Olesen, TR Hammond, ... GLIA 69, E432-E433, 2021 | | 2021 |
Control of Osteocytogenesis by a Neuronally-expressed Sp7-dependent Genetic Network J Wang, T Kamath, E Macosko, H Kronenberg, M Wein JOURNAL OF BONE AND MINERAL RESEARCH 35, 4-4, 2020 | | 2020 |
DNA polymerase beta inhibitor pamoic acid: toxicity to metakaryotic human cancer stem cells (HT-29) TV Kamath Massachusetts Institute of Technology, 2016 | | 2016 |