| Parkinson’s disease is a type of amyloidosis featuring accumulation of amyloid fibrils of α-synuclein K Araki, N Yagi, K Aoyama, CJ Choong, H Hayakawa, H Fujimura, ... Proceedings of the National Academy of Sciences 116 (36), 17963-17969, 2019 | 153 | 2019 |
| Parkinson’s disease and iron H Mochizuki, CJ Choong, K Baba Journal of Neural Transmission 127, 181-187, 2020 | 115 | 2020 |
| Amido-bridged nucleic acid (AmNA)-modified antisense oligonucleotides targeting α-synuclein as a novel therapy for Parkinson’s disease T Uehara, CJ Choong, M Nakamori, H Hayakawa, K Nishiyama, ... Scientific reports 9 (1), 7567, 2019 | 99 | 2019 |
| Synchrotron FTIR micro-spectroscopy for structural analysis of Lewy bodies in the brain of Parkinson’s disease patients K Araki, N Yagi, Y Ikemoto, H Yagi, CJ Choong, H Hayakawa, G Beck, ... Scientific reports 5 (1), 17625, 2015 | 98 | 2015 |
| Gene therapy for neurological disorders CJ Choong, K Baba, H Mochizuki Expert opinion on biological therapy 16 (2), 143-159, 2016 | 87 | 2016 |
| Alternative mitochondrial quality control mediated by extracellular release CJ Choong, T Okuno, K Ikenaka, K Baba, H Hayakawa, M Koike, ... Autophagy 17 (10), 2962-2974, 2021 | 84 | 2021 |
| A novel histone deacetylase 1 and 2 isoform-specific inhibitor alleviates experimental Parkinson's disease CJ Choong, T Sasaki, H Hayakawa, T Yasuda, K Baba, Y Hirata, ... Neurobiology of aging 37, 103-116, 2016 | 61 | 2016 |
| A refined concept: α-synuclein dysregulation disease H Mochizuki, CJ Choong, E Masliah Neurochemistry international 119, 84-96, 2018 | 41 | 2018 |
| Neuroprotection of α-synuclein under acute and chronic rotenone and maneb treatment is abolished by its familial Parkinson's disease mutations A30P, A53T and E46K CJ Choong, YH Say Neurotoxicology 32 (6), 857-863, 2011 | 40 | 2011 |
| Neuropathology of α‐synuclein in Parkinson's disease CJ Choong, H Mochizuki Neuropathology 42 (2), 93-103, 2022 | 36 | 2022 |
| Neurodegenerative changes initiated by presynaptic dysfunction T Yasuda, Y Nakata, CJ Choong, H Mochizuki Translational neurodegeneration 2, 1-5, 2013 | 36 | 2013 |
| Structurally distinct α‐synuclein fibrils induce robust parkinsonian pathology H Hayakawa, R Nakatani, K Ikenaka, C Aguirre, CJ Choong, H Tsuda, ... Movement Disorders 35 (2), 256-267, 2020 | 34 | 2020 |
| Gene therapy targeting mitochondrial pathway in Parkinson’s disease CJ Choong, H Mochizuki Journal of neural transmission 124, 193-207, 2017 | 33 | 2017 |
| New 5-aryl-substituted 2-aminobenzamide-type HDAC inhibitors with a diketopiperazine group and their ameliorating effects on ischemia-induced neuronal cell death Y Hirata, T Sasaki, H Kanki, CJ Choong, K Nishiyama, G Kubo, A Hotei, ... Scientific Reports 8 (1), 1400, 2018 | 24 | 2018 |
| The promises of stem cells: stem cell therapy for movement disorders H Mochizuki, CJ Choong, T Yasuda Parkinsonism & related disorders 20, S128-S131, 2014 | 22 | 2014 |
| Involvement of mitochondria in Parkinson’s disease CJ Choong, H Mochizuki International Journal of Molecular Sciences 24 (23), 17027, 2023 | 21 | 2023 |
| Two-step screening method to identify α-synuclein aggregation inhibitors for Parkinson’s disease M Hideshima, Y Kimura, C Aguirre, K Kakuda, T Takeuchi, CJ Choong, ... Scientific reports 12 (1), 351, 2022 | 21 | 2022 |
| Lysophagy protects against propagation of α-synuclein aggregation through ruptured lysosomal vesicles K Kakuda, K Ikenaka, A Kuma, J Doi, C Aguirre, N Wang, T Ajiki, ... Proceedings of the National Academy of Sciences 121 (1), e2312306120, 2024 | 18 | 2024 |
| Phosphatidylinositol-3, 4, 5-trisphosphate interacts with alpha-synuclein and initiates its aggregation and formation of Parkinson’s disease-related fibril polymorphism CJ Choong, C Aguirre, K Kakuda, G Beck, H Nakanishi, Y Kimura, ... Acta Neuropathologica 145 (5), 573-595, 2023 | 16 | 2023 |
| Single injection of sustained-release prostacyclin analog ONO-1301-MS ameliorates hypoxic toxicity in the murine model of amyotrophic lateral sclerosis S Tada, T Okuno, M Shimizu, Y Sakai, H Sumi-Akamaru, M Kinoshita, ... Scientific reports 9 (1), 5252, 2019 | 15 | 2019 |
