Targeting the thioredoxin system for cancer therapy J Zhang, X Li, X Han, R Liu, J Fang Trends in pharmacological sciences 38 (9), 794-808, 2017 | 418 | 2017 |
Nrf2: a dark horse in Alzheimer's disease treatment A Osama, J Zhang, J Yao, X Yao, J Fang Ageing research reviews 64, 101206, 2020 | 195 | 2020 |
Small molecule inhibitors of mammalian thioredoxin reductase as potential anticancer agents: An update J Zhang, B Zhang, X Li, X Han, R Liu, J Fang Medicinal research reviews 39 (1), 5-39, 2019 | 155 | 2019 |
Small molecules regulating reactive oxygen species homeostasis for cancer therapy J Zhang, D Duan, ZL Song, T Liu, Y Hou, J Fang Medicinal Research Reviews 41 (1), 342-394, 2021 | 154 | 2021 |
Gut microbiota modulates drug pharmacokinetics J Zhang, J Zhang, R Wang Drug metabolism reviews 50 (3), 357-368, 2018 | 138 | 2018 |
Targeting thioredoxin reductase by parthenolide contributes to inducing apoptosis of HeLa cells D Duan, J Zhang, J Yao, Y Liu, J Fang Journal of Biological Chemistry 291 (19), 10021-10031, 2016 | 125 | 2016 |
Inhibition of thioredoxin reductase by alantolactone prompts oxidative stress-mediated apoptosis of HeLa cells J Zhang, Y Li, D Duan, J Yao, K Gao, J Fang Biochemical Pharmacology 102, 34-44, 2016 | 105 | 2016 |
Selenium deficiency-induced redox imbalance leads to metabolic reprogramming and inflammation in the liver C Tang, S Li, K Zhang, J Li, Y Han, T Zhan, Q Zhao, X Guo, J Zhang Redox biology 36, 101519, 2020 | 103 | 2020 |
Thioredoxin reductase inhibitors: a patent review B Zhang, J Zhang, S Peng, R Liu, X Li, Y Hou, X Han, J Fang Expert opinion on therapeutic patents 27 (5), 547-556, 2017 | 99 | 2017 |
Biologically active indolizidine alkaloids J Zhang, SL Morris‐Natschke, D Ma, XF Shang, CJ Yang, YQ Liu, KH Lee Medicinal Research Reviews 41 (2), 928-960, 2021 | 73 | 2021 |
Natural molecules targeting thioredoxin system and their therapeutic potential J Zhang, D Duan, A Osama, J Fang Antioxidants & Redox Signaling 34 (14), 1083-1107, 2021 | 70 | 2021 |
Promotion of HeLa cells apoptosis by cynaropicrin involving inhibition of thioredoxin reductase and induction of oxidative stress T Liu, J Zhang, X Han, J Xu, Y Wu, J Fang Free Radical Biology and Medicine 135, 216-226, 2019 | 64 | 2019 |
Plateau hypoxia attenuates the metabolic activity of intestinal flora to enhance the bioavailability of nifedipine J Zhang, Y Chen, Y Sun, R Wang, J Zhang, Z Jia Drug delivery 25 (1), 1175-1181, 2018 | 62 | 2018 |
Isolation, identification, and activity evaluation of chemical constituents from soil fungus Fusarium avenaceum SF-1502 and endophytic fungus Fusarium proliferatum AF-04 CX Jiang, J Li, JM Zhang, XJ Jin, B Yu, JG Fang, QX Wu Journal of agricultural and food chemistry 67 (7), 1839-1846, 2019 | 60 | 2019 |
Extraction and purification of total flavonoids from pine needles of Cedrus deodara contribute to anti-tumor in vitro X Shi, D Liu, J Zhang, P Hu, W Shen, B Fan, Q Ma, X Wang BMC complementary and alternative medicine 16, 1-9, 2016 | 58 | 2016 |
Securinine disturbs redox homeostasis and elicits oxidative stress-mediated apoptosis via targeting thioredoxin reductase J Zhang, J Yao, S Peng, X Li, J Fang Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (1), 129-138, 2017 | 50 | 2017 |
A fast response and red emission probe for mammalian thioredoxin reductase H Ma, J Zhang, Z Zhang, Y Liu, J Fang Chemical Communications 52 (81), 12060-12063, 2016 | 50 | 2016 |
Redox-dependent copper carrier promotes cellular copper uptake and oxidative stress-mediated apoptosis of cancer cells J Zhang, D Duan, J Xu, J Fang ACS applied materials & interfaces 10 (39), 33010-33021, 2018 | 45 | 2018 |
Xanthatin promotes apoptosis via inhibiting thioredoxin reductase and eliciting oxidative stress R Liu, D Shi, J Zhang, X Li, X Han, X Yao, J Fang Molecular Pharmaceutics 15 (8), 3285-3296, 2018 | 41 | 2018 |
Thioredoxin signaling pathways in cancer J Zhang, X Li, Z Zhao, W Cai, J Fang Antioxidants & Redox Signaling 38 (4), 403-424, 2023 | 39 | 2023 |