Multi-parameter analysis of the kinetics of NF-κB signalling and transcription in single living cells G Nelson, L Paraoan, DG Spiller, GJC Wilde, MA Browne, PK Djali, ... Journal of cell science 115 (6), 1137-1148, 2002 | 148 | 2002 |
Directional protein secretion by the retinal pigment epithelium: roles in retinal health and the development of age‐related macular degeneration P Kay, YC Yang, L Paraoan Journal of cellular and molecular medicine 17 (7), 833-843, 2013 | 111 | 2013 |
Pathobiology of epiretinal and subretinal membranes: possible roles for the matricellular proteins thrombospondin 1 and osteonectin (SPARC) P Hiscott, S Hagan, L Heathcote, CM Sheridan, CP Groenewald, ... Eye 16 (4), 393-403, 2002 | 103 | 2002 |
An integrative analysis of the age-associated multi-omic landscape across cancers K Chatsirisupachai, T Lesluyes, L Paraoan, P Van Loo, JP De Magalhães Nature communications 12 (1), 2345, 2021 | 102 | 2021 |
Thrombospondin 1, thrombospondin 2 and the eye P Hiscott, L Paraoan, A Choudhary, JL Ordonez, A Al-Khaier, ... Progress in retinal and eye research 25 (1), 1-18, 2006 | 100 | 2006 |
Cystatin C prevents degeneration of rat nigral dopaminergic neurons: in vitro and in vivo studies L Xu, J Sheng, Z Tang, X Wu, Y Yu, H Guo, Y Shen, C Zhou, L Paraoan, ... Neurobiology of disease 18 (1), 152-165, 2005 | 82 | 2005 |
Identification, expression and functional characterization of the GRAL gene Z Li, B Wang, X Wu, SY Cheng, L Paraoan, J Zhou Journal of neurochemistry 95 (2), 361-376, 2005 | 73 | 2005 |
Inducers of cross-linked actin networks in trabecular meshwork cells S O'Reilly, N Pollock, L Currie, L Paraoan, AF Clark, I Grierson Investigative ophthalmology & visual science 52 (10), 7316-7324, 2011 | 71 | 2011 |
P53 apoptosis mediator PERP: localization, function and caspase activation in uveal melanoma L Davies, D Gray, D Spiller, MRH White, B Damato, I Grierson, L Paraoan Journal of cellular and molecular medicine 13 (8b), 1995-2007, 2009 | 64 | 2009 |
Unexpected intracellular localization of the AMD‐associated cystatin C variant L Paraoan, A Ratnayaka, DG Spiller, P Hiscott, MRH White, I Grierson Traffic 5 (11), 884-895, 2004 | 60 | 2004 |
Whole-genome methylation profiling of the retinal pigment epithelium of individuals with age-related macular degeneration reveals differential methylation of the SKI, GTF2H4 … LF Porter, N Saptarshi, Y Fang, S Rathi, AI Den Hollander, EK De Jong, ... Clinical epigenetics 11, 1-14, 2019 | 56 | 2019 |
Cystatin C in macular and neuronal degenerations: Implications for mechanism (s) of age-related macular degeneration L Paraoan, P Hiscott, C Gosden, I Grierson Vision research 50 (7), 737-742, 2010 | 49 | 2010 |
Cross-linked actin networks (CLANs) in bovine trabecular meshwork cells NC Wade, I Grierson, S O'reilly, MJ Hoare, KPB Cracknell, LI Paraoan, ... Experimental eye research 89 (5), 648-659, 2009 | 45 | 2009 |
Analysis of expressed sequence tags of retinal pigment epithelium: cystatin C is an abundant transcript L Paraoan, I Grierson, BEH Maden The international journal of biochemistry & cell biology 32 (4), 417-426, 2000 | 45 | 2000 |
PERP expression stabilizes active p53 via modulation of p53-MDM2 interaction in uveal melanoma cells L Davies, D Spiller, MRH White, I Grierson, L Paraoan Cell death & disease 2 (3), e136-e136, 2011 | 42 | 2011 |
Cathepsin S and its inhibitor cystatin C: imbalance in uveal melanoma L Paraoan, D Gray, P Hiscott, M Garcia-Finana, B Lane, B Damato, ... Front Biosci (Landmark Ed) 14, 2504-2513, 2009 | 38 | 2009 |
p63 is required beside p53 for PERP-mediated apoptosis in uveal melanoma R Awais, DG Spiller, MRH White, L Paraoan British Journal of Cancer 115 (8), 983-992, 2016 | 36 | 2016 |
A missense variant in CST3 exerts a recessive effect on susceptibility to age-related macular degeneration resembling its association with Alzheimer’s disease JM Butler, U Sharif, M Ali, M McKibbin, JP Thompson, R Gale, YC Yang, ... Human genetics 134, 705-715, 2015 | 36 | 2015 |
Expression of p53-induced apoptosis effector PERP in primary uveal melanomas: downregulation is associated with aggressive type L Paraoan, D Gray, P Hiscott, B Ebrahimi, B Damato, I Grierson Experimental eye research 83 (4), 911-919, 2006 | 36 | 2006 |
Protective Effects of Curcumin Ester Prodrug, Curcumin Diethyl Disuccinate against H2O2-Induced Oxidative Stress in Human Retinal Pigment Epithelial Cells … C Muangnoi, U Sharif, P Ratnatilaka Na Bhuket, P Rojsitthisak, L Paraoan International Journal of Molecular Sciences 20 (13), 3367, 2019 | 34 | 2019 |