A non-canonical vitamin K cycle is a potent ferroptosis suppressor E Mishima, J Ito, Z Wu, T Nakamura, A Wahida, S Doll, W Tonnus, ... Nature 608 (7924), 778-783, 2022 | 433 | 2022 |
Origin and consequences of necroinflammation M Sarhan, WG Land, W Tonnus, CP Hugo, A Linkermann Physiological reviews 98 (2), 727-780, 2018 | 199 | 2018 |
Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury W Tonnus, C Meyer, C Steinebach, A Belavgeni, A von Mässenhausen, ... Nature communications 12 (1), 4402, 2021 | 193 | 2021 |
Caspase-8–dependent gasdermin D cleavage promotes antimicrobial defense but confers susceptibility to TNF-induced lethality B Demarco, JP Grayczyk, E Bjanes, D Le Roy, W Tonnus, ... Science advances 6 (47), eabc3465, 2020 | 192 | 2020 |
The pathological features of regulated necrosis W Tonnus, C Meyer, A Paliege, A Belavgeni, A von Mässenhausen, ... The Journal of pathology 247 (5), 697-707, 2019 | 168 | 2019 |
The in vivo evidence for regulated necrosis W Tonnus, A Linkermann Immunological reviews 277 (1), 128-149, 2017 | 124 | 2017 |
Targeting ferroptosis protects against experimental (multi) organ dysfunction and death S Van Coillie, E Van San, I Goetschalckx, B Wiernicki, B Mukhopadhyay, ... Nature communications 13 (1), 1046, 2022 | 104 | 2022 |
Exquisite sensitivity of adrenocortical carcinomas to induction of ferroptosis A Belavgeni, SR Bornstein, A Von Mässenhausen, W Tonnus, J Stumpf, ... Proceedings of the National Academy of Sciences 116 (44), 22269-22274, 2019 | 101 | 2019 |
Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury S Martens, M Jeong, W Tonnus, F Feldmann, S Hofmans, V Goossens, ... Cell death & disease 8 (6), e2904-e2904, 2017 | 84 | 2017 |
Cellular and humoral immune responses after 3 doses of BNT162b2 mRNA SARS-CoV-2 vaccine in kidney transplant J Stumpf, W Tonnus, A Paliege, R Rettig, A Steglich, F Gembardt, ... Transplantation 105 (11), e267-e269, 2021 | 80 | 2021 |
Dexamethasone sensitizes to ferroptosis by glucocorticoid receptor–induced dipeptidase-1 expression and glutathione depletion A von Mässenhausen, N Zamora Gonzalez, F Maremonti, A Belavgeni, ... Science advances 8 (5), eabl8920, 2022 | 68 | 2022 |
Phenytoin inhibits necroptosis A Von Mässenhausen, W Tonnus, N Himmerkus, S Parmentier, D Saleh, ... Cell death & disease 9 (3), 359, 2018 | 67 | 2018 |
The role of regulated necrosis in endocrine diseases W Tonnus, A Belavgeni, F Beuschlein, G Eisenhofer, M Fassnacht, ... Nature Reviews Endocrinology 17 (8), 497-510, 2021 | 61 | 2021 |
“Death is my Heir”—ferroptosis connects cancer pharmacogenomics and ischemia-reperfusion injury W Tonnus, A Linkermann Cell Chemical Biology 23 (2), 202-203, 2016 | 53 | 2016 |
Cell death pathways drive necroinflammation during acute kidney injury A von Mässenhausen, W Tonnus, A Linkermann Nephron 140 (2), 144-147, 2018 | 49 | 2018 |
P2X1, P2X4, and P2X7 Receptor Knock Out Mice Expose Differential Outcome of Sepsis Induced by α-Haemolysin Producing Escherichia coli AS Greve, M Skals, SK Fagerberg, W Tonnus, S Ellermann-Eriksen, ... Frontiers in Cellular and Infection Microbiology 7, 113, 2017 | 49 | 2017 |
Ferroptosis in Health and Disease C Berndt, H Alborzinia, VS Amen, S Ayton, U Barayeu, A Bartelt, H Bayir, ... Redox Biology, 103211, 2024 | 48 | 2024 |
The clinical relevance of necroinflammation—highlighting the importance of acute kidney injury and the adrenal glands W Tonnus, F Gembardt, M Latk, S Parmentier, C Hugo, SR Bornstein, ... Cell Death & Differentiation 26 (1), 68-82, 2019 | 42 | 2019 |
Gasdermin D-deficient mice are hypersensitive to acute kidney injury W Tonnus, F Maremonti, A Belavgeni, M Latk, Y Kusunoki, A Brucker, ... Cell death & disease 13 (9), 792, 2022 | 37 | 2022 |
Gasdermin D and pyroptosis in acute kidney injury W Tonnus, A Linkermann Kidney international 96 (5), 1061-1063, 2019 | 33* | 2019 |