| Distinct factors control histone variant H3. 3 localization at specific genomic regions AD Goldberg, LA Banaszynski, KM Noh, PW Lewis, SJ Elsaesser, ... Cell 140 (5), 678-691, 2010 | 1436 | 2010 |
| Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma PW Lewis, MM Müller, MS Koletsky, F Cordero, S Lin, LA Banaszynski, ... Science 340 (6134), 857-861, 2013 | 1382 | 2013 |
| Daxx is an H3. 3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres PW Lewis, SJ Elsaesser, KM Noh, SC Stadler, CD Allis Proceedings of the National Academy of Sciences 107 (32), 14075-14080, 2010 | 936 | 2010 |
| Isolation of the Cdc45/Mcm2–7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase SE Moyer, PW Lewis, MR Botchan Proceedings of the National Academy of Sciences 103 (27), 10236-10241, 2006 | 869 | 2006 |
| Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations P Buczkowicz, C Hoeman, P Rakopoulos, S Pajovic, L Letourneau, ... Nature genetics 46 (5), 451-456, 2014 | 662 | 2014 |
| Use of human embryonic stem cells to model pediatric gliomas with H3. 3K27M histone mutation K Funato, T Major, PW Lewis, CD Allis, V Tabar Science 346 (6216), 1529-1533, 2014 | 417 | 2014 |
| Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape C Lu, SU Jain, D Hoelper, D Bechet, RC Molden, L Ran, D Murphy, ... Science 352 (6287), 844-849, 2016 | 405 | 2016 |
| H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis AS Harutyunyan, B Krug, H Chen, S Papillon-Cavanagh, M Zeinieh, ... Nature communications 10 (1), 1262, 2019 | 315 | 2019 |
| Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex PW Lewis, EL Beall, TC Fleischer, D Georlette, AJ Link, MR Botchan Genes & development 18 (23), 2929-2940, 2004 | 314 | 2004 |
| ATRX ADD domain links an atypical histone methylation recognition mechanism to human mental-retardation syndrome S Iwase, B Xiang, S Ghosh, T Ren, PW Lewis, JC Cochrane, CD Allis, ... Nature structural & molecular biology 18 (7), 769-776, 2011 | 305 | 2011 |
| DAXX envelops a histone H3. 3–H4 dimer for H3. 3-specific recognition SJ Elsässer, H Huang, PW Lewis, JW Chin, CD Allis, DJ Patel Nature 491 (7425), 560-565, 2012 | 291 | 2012 |
| Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas S Papillon-Cavanagh, C Lu, T Gayden, LG Mikael, D Bechet, ... Nature genetics 49 (2), 180-185, 2017 | 255 | 2017 |
| KDM4A lysine demethylase induces site-specific copy gain and rereplication of regions amplified in tumors JC Black, AL Manning, C Van Rechem, J Kim, B Ladd, J Cho, CM Pineda, ... Cell 154 (3), 541-555, 2013 | 249 | 2013 |
| ATRX, DAXX or MEN1 mutant pancreatic neuroendocrine tumors are a distinct alpha-cell signature subgroup CS Chan, SV Laddha, PW Lewis, MS Koletsky, K Robzyk, E Da Silva, ... Nature communications 9 (1), 4158, 2018 | 202 | 2018 |
| Pervasive H3K27 acetylation leads to ERV expression and a therapeutic vulnerability in H3K27M gliomas B Krug, N De Jay, AS Harutyunyan, S Deshmukh, DM Marchione, ... Cancer cell 35 (5), 782-797. e8, 2019 | 197 | 2019 |
| PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism SU Jain, TJ Do, PJ Lund, AQ Rashoff, KL Diehl, M Cieslik, A Bajic, ... Nature communications 10 (1), 2146, 2019 | 193 | 2019 |
| Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas J Bayliss, P Mukherjee, C Lu, SU Jain, C Chung, D Martinez, B Sabari, ... Science translational medicine 8 (366), 366ra161-366ra161, 2016 | 188 | 2016 |
| Genomic profiling and expression studies reveal both positive and negative activities for the Drosophila Myb–MuvB/dREAM complex in proliferating cells D Georlette, S Ahn, DM MacAlpine, E Cheung, PW Lewis, EL Beall, ... Genes & development 21 (22), 2880-2896, 2007 | 182 | 2007 |
| Histone variants in metazoan development LA Banaszynski, CD Allis, PW Lewis Developmental cell 19 (5), 662-674, 2010 | 177 | 2010 |
| Specific detection of methionine 27 mutation in histone 3 variants (H3K27M) in fixed tissue from high-grade astrocytomas D Bechet, GGH Gielen, A Korshunov, SM Pfister, C Rousso, D Faury, ... Acta neuropathologica 128, 733-741, 2014 | 152 | 2014 |