IL-15Rα recycles and presents IL-15 in trans to neighboring cells S Dubois, J Mariner, TA Waldmann, Y Tagaya Immunity 17 (5), 537-547, 2002 | 1146 | 2002 |
Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human … KC Conlon, E Lugli, HC Welles, SA Rosenberg, AT Fojo, JC Morris, ... Journal of clinical oncology 33 (1), 74-82, 2015 | 764 | 2015 |
Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for immunotherapy TA Waldmann, S Dubois, Y Tagaya Immunity 14 (2), 105-110, 2001 | 618 | 2001 |
IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice J Marks-Konczalik, S Dubois, JM Losi, H Sabzevari, N Yamada, ... Proceedings of the National Academy of Sciences 97 (21), 11445-11450, 2000 | 536 | 2000 |
Role of trans-cellular IL-15 presentation in the activation of NK cell–mediated killing, which leads to enhanced tumor immunosurveillance H Kobayashi, S Dubois, N Sato, H Sabzevari, Y Sakai, TA Waldmann, ... Blood 105 (2), 721-727, 2005 | 347 | 2005 |
Preassociation of IL-15 with IL-15Rα-IgG1-Fc enhances its activity on proliferation of NK and CD8+/CD44high T cells and its antitumor action S Dubois, HJ Patel, M Zhang, TA Waldmann, JR Müller The Journal of Immunology 180 (4), 2099-2106, 2008 | 264 | 2008 |
IL-15 in the combination immunotherapy of cancer TA Waldmann, S Dubois, MD Miljkovic, KC Conlon Frontiers in immunology 11, 868, 2020 | 194 | 2020 |
The IL-15/IL-15Rα on cell surfaces enables sustained IL-15 activity and contributes to the long survival of CD8 memory T cells N Sato, HJ Patel, TA Waldmann, Y Tagaya Proceedings of the National Academy of Sciences 104 (2), 588-593, 2007 | 188 | 2007 |
IL-15 enhanced antibody-dependent cellular cytotoxicity mediated by NK cells and macrophages M Zhang, B Wen, OM Anton, Z Yao, S Dubois, W Ju, N Sato, DJ DiLillo, ... Proceedings of the National Academy of Sciences 115 (46), E10915-E10924, 2018 | 158 | 2018 |
Interleukin-15 combined with an anti-CD40 antibody provides enhanced therapeutic efficacy for murine models of colon cancer M Zhang, Z Yao, S Dubois, W Ju, JR Müller, TA Waldmann Proceedings of the National Academy of Sciences 106 (18), 7513-7518, 2009 | 157 | 2009 |
Natural splicing of exon 2 of human interleukin-15 receptor α-chain mRNA results in a shortened form with a distinct pattern of expression S Dubois, F Magrangeas, P Lehours, S Raher, J Bernard, O Boisteau, ... Journal of Biological Chemistry 274 (38), 26978-26984, 1999 | 131 | 1999 |
Survival adjustment of mature dendritic cells by IL-15 SP Dubois, TA Waldmann, JR Müller Proceedings of the National Academy of Sciences 102 (24), 8662-8667, 2005 | 128 | 2005 |
IL15 by continuous intravenous infusion to adult patients with solid tumors in a phase I trial induced dramatic NK-cell subset expansion KC Conlon, EL Potter, S Pittaluga, CCR Lee, MD Miljkovic, TA Fleisher, ... Clinical Cancer Research 25 (16), 4945-4954, 2019 | 124 | 2019 |
Targeting the HTLV-I-regulated BATF3/IRF4 transcriptional network in adult T cell leukemia/lymphoma M Nakagawa, AL Shaffer, M Ceribelli, M Zhang, G Wright, W Xiao, ... Cancer Cell 34 (2), 286-297. e10, 2018 | 115 | 2018 |
Molecular cloning of two isoforms of a receptor for the human hematopoietic cytokine interleukin-11 M Cherel, M Sorel, B Lebeau, S Dubois, JF Moreau, R Bataille, ... | 111 | 1995 |
ITK and IL-15 support two distinct subsets of CD8+ T cells S Dubois, TA Waldmann, JR Müller Proceedings of the National Academy of Sciences 103 (32), 12075-12080, 2006 | 100 | 2006 |
IL15 Infusion of Cancer Patients Expands the Subpopulation of Cytotoxic CD56bright NK Cells and Increases NK-Cell Cytokine Release Capabilities S Dubois, KC Conlon, JR Müller, J Hsu-Albert, N Beltran, BR Bryant, ... Cancer immunology research 5 (10), 929-938, 2017 | 81 | 2017 |
Cotranscription and intergenic splicing of human galactose-1-phosphate uridylyltransferase and interleukin-11 receptor α-chain genes generate a fusion mRNA in normal cells … F Magrangeas, G Pitiot, S Dubois, E Bragado-Nilsson, M Cherel, S Jobert, ... Journal of Biological Chemistry 273 (26), 16005-16010, 1998 | 78 | 1998 |
Interleukin‐15 expression in cutaneous T‐cell lymphoma (mycosis fungoides and Sézary syndrome) S Leroy, S Dubois, I Tenaud, N Chebassier, A Godard, Y Jacques, ... British Journal of Dermatology 144 (5), 1016-1023, 2001 | 67 | 2001 |
Development of an IL-15–autocrine CD8 T-cell leukemia in IL-15–transgenic mice requires the cis expression of IL-15Rα N Sato, H Sabzevari, S Fu, W Ju, MN Petrus, RN Bamford, TA Waldmann, ... Blood, The Journal of the American Society of Hematology 117 (15), 4032-4040, 2011 | 64 | 2011 |