| Ubistatins inhibit proteasome-dependent degradation by binding the ubiquitin chain R Verma, NR Peters, M D'Onofrio, GP Tochtrop, KM Sakamoto, ... Science 306 (5693), 117-120, 2004 | 237 | 2004 |
| A small molecule agonist of EphA2 receptor tyrosine kinase inhibits tumor cell migration in vitro and prostate cancer metastasis in vivo A Petty, E Myshkin, H Qin, H Guo, H Miao, GP Tochtrop, JT Hsieh, P Page, ... Public Library of Science 7 (8), e42120, 2012 | 140 | 2012 |
| Genetic ablation of the fatty acid–binding protein FABP5 suppresses HER2-induced mammary tumorigenesis L Levi, G Lobo, MK Doud, J Von Lintig, D Seachrist, GP Tochtrop, N Noy Cancer research 73 (15), 4770-4780, 2013 | 128 | 2013 |
| Energetics by NMR: site-specific binding in a positively cooperative system GP Tochtrop, K Richter, C Tang, JJ Toner, DF Covey, DP Cistola Proceedings of the National Academy of Sciences 99 (4), 1847-1852, 2002 | 114 | 2002 |
| Metabolomics, pathway regulation, and pathway discovery GF Zhang, S Sadhukhan, GP Tochtrop, H Brunengraber Journal of biological chemistry 286 (27), 23631-23635, 2011 | 92 | 2011 |
| Catabolism of 4-Hydroxyacids and 4-Hydroxynonenal via 4-Hydroxy-4-phosphoacyl-CoAs*♦ GF Zhang, RS Kombu, T Kasumov, Y Han, S Sadhukhan, J Zhang, ... Journal of Biological Chemistry 284 (48), 33521-33534, 2009 | 91 | 2009 |
| Molecular pharmacodynamics of emixustat in protection against retinal degeneration J Zhang, PD Kiser, M Badiee, G Palczewska, Z Dong, M Golczak, ... The Journal of clinical investigation 125 (7), 2781-2794, 2015 | 87 | 2015 |
| Catalytic mechanism of a retinoid isomerase essential for vertebrate vision PD Kiser, J Zhang, M Badiee, Q Li, W Shi, X Sui, M Golczak, GP Tochtrop, ... Nature chemical biology 11 (6), 409-415, 2015 | 85 | 2015 |
| Isotopomer enrichment assay for very short chain fatty acids and its metabolic applications K Tomcik, RA Ibarra, S Sadhukhan, Y Han, GP Tochtrop, GF Zhang Analytical biochemistry 410 (1), 110-117, 2011 | 74 | 2011 |
| A single hydroxyl group governs ligand site selectivity in human ileal bile acid binding protein GP Tochtrop, GT DeKoster, DF Covey, DP Cistola Journal of the American Chemical Society 126 (35), 11024-11029, 2004 | 67 | 2004 |
| Determinants of cooperativity and site selectivity in human ileal bile acid binding protein O Toke, JD Monsey, GT DeKoster, GP Tochtrop, C Tang, DP Cistola Biochemistry 45 (3), 727-737, 2006 | 65 | 2006 |
| A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration Y Chen, Y Chen, B Jastrzebska, M Golczak, S Gulati, H Tang, W Seibel, ... Nature communications 9 (1), 1976, 2018 | 62 | 2018 |
| Target identification strategies in chemical genetics GP Tochtrop, RW King Combinatorial Chemistry & High Throughput Screening 7 (7), 677-688, 2004 | 48 | 2004 |
| Steroid ring hydroxylation patterns govern cooperativity in human bile acid binding protein GP Tochtrop, JL Bruns, C Tang, DF Covey, DP Cistola Biochemistry 42 (40), 11561-11567, 2003 | 48 | 2003 |
| Inter-relations between 3-hydroxypropionate and propionate metabolism in rat liver: relevance to disorders of propionyl-CoA metabolism KA Wilson, Y Han, M Zhang, JP Hess, KA Chapman, GW Cline, ... American Journal of Physiology-Endocrinology and Metabolism 313 (4), E413-E428, 2017 | 46 | 2017 |
| Photocyclic behavior of rhodopsin induced by an atypical isomerization mechanism S Gulati, B Jastrzebska, S Banerjee, ÁL Placeres, P Miszta, S Gao, ... Proceedings of the National Academy of Sciences 114 (13), E2608-E2615, 2017 | 39 | 2017 |
| Using isotopic tools to dissect and quantitate parallel metabolic pathways S Sadhukhan, Y Han, GF Zhang, H Brunengraber, GP Tochtrop Journal of the American Chemical Society 132 (18), 6309-6311, 2010 | 39 | 2010 |
| Structure and spectroscopy of alkene-cleaving dioxygenases containing an atypically coordinated non-heme iron center X Sui, AC Weitz, ER Farquhar, M Badiee, S Banerjee, J von Lintig, ... Biochemistry 56 (22), 2836-2852, 2017 | 35 | 2017 |
| Mapping the locations of estradiol and potent neuroprotective analogues in phospholipid bilayers by REDOR L Cegelski, CV Rice, RD O'Connor, AL Caruano, GP Tochtrop, ZY Cai, ... Drug development research 66 (2), 93-102, 2005 | 34 | 2005 |
| Molecular library synthesis using complex substrates: expanding the framework of triterpenoids VA Ignatenko, Y Han, GP Tochtrop The Journal of organic chemistry 78 (2), 410-418, 2013 | 33 | 2013 |
