MLL-Rearranged Acute Leukemia with t (4; 11)(q21; q23)—Current Treatment Options. Is There a Role for CAR-T Cell Therapy? O Britten, D Ragusa, S Tosi, Y Mostafa Kamel Cells 8 (11), 1341, 2019 | 84 | 2019 |
Folate deficiency as predisposing factor for childhood leukaemia: a review of the literature CD Cantarella, D Ragusa, M Giammanco, S Tosi Genes & nutrition 12, 1-15, 2017 | 64 | 2017 |
Deletions of Chromosome 7q Affect Nuclear Organization and HLXB9Gene Expression in Hematological Disorders C Federico, T Owoka, D Ragusa, V Sturiale, D Caponnetto, CG Leotta, ... Cancers 11 (4), 585, 2019 | 14 | 2019 |
Chromosomal Rearrangements and Altered Nuclear Organization: Recent Mechanistic Models in Cancer C Federico, F Bruno, D Ragusa, CS Clements, D Brancato, MP Henry, ... Cancers 13 (22), 5860, 2021 | 12 | 2021 |
From FISH to Hi-C: The Chromatin Architecture of the Chromosomal Region 7q36. 3, Frequently Rearranged in Leukemic Cells, Is Evolutionary Conserved GM Gulino, F Bruno, V Sturiale, D Brancato, D Ragusa, S Tosi, S Saccone, ... International Journal of Molecular Sciences 22 (5), 2338, 2021 | 11 | 2021 |
Engineered model of t (7; 12)(q36; p13) AML recapitulates patient-specific features and gene expression profiles D Ragusa, Y Cicirò, C Federico, S Saccone, F Bruno, R Saeedi, C Sisu, ... Oncogenesis 11 (1), 50, 2022 | 10 | 2022 |
Mechanisms associated with t (7; 12) acute myeloid leukaemia: from genetics to potential treatment targets D Ragusa, L Dijkhuis, C Pina, S Tosi Bioscience Reports 43 (1), BSR20220489, 2023 | 9 | 2023 |
The RS4; 11 cell line as a model for leukaemia with t (4; 11)(q21; q23): Revised characterisation of cytogenetic features D Ragusa, EM Makarov, O Britten, D Moralli, CM Green, S Tosi Cancer Reports 2 (5), e1207, 2019 | 9 | 2019 |
Contribution of histone variants to aneuploidy: a cancer perspective D Ragusa, P Vagnarelli Frontiers in Genetics 14, 2023 | 6 | 2023 |
Expression of the checkpoint kinase BUB1 is a predictor of response to cancer therapies Y Cicirò, D Ragusa, A Sala Scientific Reports 14 (1), 4461, 2024 | 5 | 2024 |
The mitotic checkpoint kinase BUB1 is a direct and actionable target of MYB in adenoid cystic carcinoma Y Cicirò, D Ragusa, PT Nevado, R Lattanzio, G Sala, T DesRochers, ... FEBS letters 598 (2), 252-265, 2024 | 5 | 2024 |
Pan-Cancer Analysis Identifies MNX1 and Associated Antisense Transcripts as Biomarkers for Cancer D Ragusa, S Tosi, C Sisu Cells 11 (22), 3577, 2022 | 5 | 2022 |
Alterations in Genome Organization in Lymphoma Cell Nuclei due to the Presence of the t (14; 18) Translocation E Garimberti, C Federico, D Ragusa, F Bruno, S Saccone, JM Bridger, ... International Journal of Molecular Sciences 25 (4), 2377, 2024 | 3 | 2024 |
Dissecting infant leukemia developmental origins with a hemogenic gastruloid model D Ragusa, CW Suen, G Torregrosa-Cortés, F Pastorino, A Johns, Y Cicirò, ... bioRxiv, 2022.10. 07.511362, 2022 | 3 | 2022 |
Haematopoietic development and HSC formation in vitro: promise and limitations of gastruloid models L Dijkhuis, A Johns, D Ragusa, SC van den Brink, C Pina Emerging Topics in Life Sciences 7 (4), 439-454, 2023 | 1 | 2023 |
3093–MODELLING MNX1-OVEREXPRESSION IN A GASTRULOID MODEL OF EMBRYONIC HAEMATOPOIESIS IDENTIFIES A CANDIDATE CELL OF ORIGIN FOR T (7; 12) AML A Johns, Y Cicirò, CC Byrne, L Dijkhuis, GA Ionescu, C Pina, D Ragusa, ... Experimental Hematology 137, 104415, 2024 | | 2024 |
3051–SEQUENTIAL SPECIFICATION OF EMBRYO-LIKE HEMATOPOIETIC WAVES IN A HEMOGENIC GASTRULOID MODEL ABLE TO ENGRAFT HEMATOPOIETIC TISSUES Y Cicirò, D Ragusa, CW Suen, GT Cortès, F Pastorino, A Johns, ... Experimental Hematology 137, 104373, 2024 | | 2024 |
MAT2A inhibition in AML unveils therapeutic potential of combining DNA demethylating agents with UPR targeting K Zeka, AV Taylor, R Samarista, D Ragusa, CW Suen, OW Cyran, ... bioRxiv, 2023.06. 05.543499, 2023 | | 2023 |
Haemogenic Gastruloids Recapitulate Developmental Haematopoiesis and Provide an Ontogeny-Relevant Context to Dissect the Origins of Infant Leukemia D Ragusa, CW Suen, G Torregrosa, L Dijkhuis, C Byrne, T Balayo, ... Blood 140 (Supplement 1), 1684-1685, 2022 | | 2022 |
Engineering of chromosomal translocations to understand infant leukaemia D Ragusa, Y Cicirò Cancer, 2022 | | 2022 |