| An integrative model of cellular states, plasticity, and genetics for glioblastoma C Neftel, J Laffy, MG Filbin, T Hara, ME Shore, GJ Rahme, AR Richman, ... Cell 178 (4), 835-849. e21, 2019 | 2066 | 2019 |
| Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma T Hara, R Chanoch-Myers, ND Mathewson, C Myskiw, L Atta, L Bussema, ... Cancer cell 39 (6), 779-792. e11, 2021 | 396 | 2021 |
| Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis ND Mathewson, O Ashenberg, I Tirosh, S Gritsch, EM Perez, S Marx, ... Cell 184 (5), 1281-1298. e26, 2021 | 307 | 2021 |
| Hallmarks of transcriptional intratumour heterogeneity across a thousand tumours A Gavish, M Tyler, AC Greenwald, R Hoefflin, D Simkin, ... Nature 618 (7965), 598-606, 2023 | 186 | 2023 |
| Heterochromatin-encoded satellite RNAs induce breast cancer Q Zhu, N Hoong, A Aslanian, T Hara, C Benner, S Heinz, KH Miga, E Ke, ... Molecular cell 70 (5), 842-853. e7, 2018 | 127 | 2018 |
| Hypoxia-inducible factor 1 regulation through cross talk between mTOR and MT1-MMP T Sakamoto, JS Weng, T Hara, S Yoshino, H Kozuka-Hata, M Oyama, ... Molecular and cellular biology, 2014 | 78 | 2014 |
| The ERK signaling target RNF126 regulates anoikis resistance in cancer cells by changing the mitochondrial metabolic flux S Yoshino, T Hara, HJ Nakaoka, A Kanamori, Y Murakami, M Seiki, ... Cell discovery 2 (1), 1-19, 2016 | 53 | 2016 |
| CTLA-4 blockade induces a microglia-Th1 cell partnership that stimulates microglia phagocytosis and anti-tumor function in glioblastoma D Chen, SK Varanasi, T Hara, K Traina, M Sun, B McDonald, ... Immunity 56 (9), 2086-2104. e8, 2023 | 45 | 2023 |
| Control of metastatic niche formation by targeting APBA3/Mint3 in inflammatory monocytes T Hara, HJ Nakaoka, T Hayashi, K Mimura, D Hoshino, M Inoue, ... Proceedings of the National Academy of Sciences 114 (22), E4416-E4424, 2017 | 41 | 2017 |
| NECAB3 promotes activation of hypoxia-inducible factor-1 during normoxia and enhances tumourigenicity of cancer cells HJ Nakaoka, T Hara, S Yoshino, A Kanamori, Y Matsui, T Shimamura, ... Scientific reports 6 (1), 22784, 2016 | 37 | 2016 |
| Deletion of the Mint3/Apba3 gene in mice abrogates macrophage functions and increases resistance to lipopolysaccharide-induced septic shock T Hara, K Mimura, T Abe, G Shioi, M Seiki, T Sakamoto Journal of Biological Chemistry 286 (37), 32542-32551, 2011 | 35 | 2011 |
| Mint3-mediated L1CAM expression in fibroblasts promotes cancer cell proliferation via integrin α5β1 and tumour growth HJ Nakaoka, Z Tanei, T Hara, JS Weng, A Kanamori, T Hayashi, H Sato, ... Oncogenesis 6 (5), e334-e334, 2017 | 32 | 2017 |
| Genetic dissection of proteolytic and non-proteolytic contributions of MT1-MMP to macrophage invasion T Hara, K Mimura, M Seiki, T Sakamoto Biochemical and biophysical research communications 413 (2), 277-281, 2011 | 22 | 2011 |
| The transcriptional hallmarks of intra-tumor heterogeneity across a thousand tumors A Gavish, M Tyler, D Simkin, D Kovarsky, LN Gonzalez Castro, D Halder, ... BioRxiv, 2021.12. 19.473368, 2021 | 20 | 2021 |
| DrugMap: A quantitative pan-cancer analysis of cysteine ligandability M Takahashi, HB Chong, S Zhang, TY Yang, MJ Lazarov, S Harry, ... Cell 187 (10), 2536-2556. e30, 2024 | 19 | 2024 |
| Mint3/Apba3 depletion ameliorates severe murine influenza pneumonia and macrophage cytokine production in response to the influenza virus T Uematsu, T Fujita, HJ Nakaoka, T Hara, N Kobayashi, Y Murakami, ... Scientific Reports 6 (1), 37815, 2016 | 19 | 2016 |
| Genetic screening of new genes responsible for cellular adaptation to hypoxia using a genome-wide shRNA library S Yoshino, T Hara, JS Weng, Y Takahashi, M Seiki, T Sakamoto Plos one 7 (4), e35590, 2012 | 18 | 2012 |
| Modeling gliomas using two recombinases T Hara, IM Verma Cancer research 79 (15), 3983-3991, 2019 | 14 | 2019 |
| Mint3 in bone marrow-derived cells promotes lung metastasis in breast cancer model mice T Hara, Y Murakami, M Seiki, T Sakamoto Biochemical and Biophysical Research Communications 490 (3), 688-692, 2017 | 13 | 2017 |
| Defining ancestry, heritability and plasticity of cellular phenotypes in somatic evolution JS Schiffman, AR D’Avino, T Prieto, Y Pang, Y Fan, S Rajagopalan, ... bioRxiv, 2022.12. 28.522128, 2022 | 9 | 2022 |