| Brain-derived neurotrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMP-activated protein kinase VB Matthews, MB Åström, MHS Chan, CR Bruce, KS Krabbe, O Prelovsek, ... Diabetologia 52, 1409-1418, 2009 | 869 | 2009 |
| HSP72 protects against obesity-induced insulin resistance J Chung, AK Nguyen, DC Henstridge, AG Holmes, MHS Chan, JL Mesa, ... Proceedings of the National Academy of Sciences 105 (5), 1739-1744, 2008 | 653 | 2008 |
| Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance VB Matthews, TL Allen, S Risis, MHS Chan, DC Henstridge, N Watson, ... Diabetologia 53, 2431-2441, 2010 | 415 | 2010 |
| Skeletal myocytes are a source of interleukin‐6 mRNA expression and protein release during contraction: evidence of fiber type specificity N Hiscock, MHS Chan, T Bisucci, IA Darby, MA Febbraio The FASEB journal 18 (9), 992-994, 2004 | 366 | 2004 |
| Cytokine gene expression in human skeletal muscle during concentric contraction: evidence that IL-8, like IL-6, is influenced by glycogen availability MHS Chan, AL Carey, MJ Watt, MA Febbraio American Journal of Physiology-Regulatory, Integrative and Comparative …, 2004 | 236 | 2004 |
| Altering dietary nutrient intake that reduces glycogen content leads to phosphorylation of nuclear p38 MAP kinase in human skeletal muscle: association with IL‐6 gene … MHS Chan, SL McGee, MJ Watt, M Hargreaves, MA Febbraio The FASEB journal 18 (14), 1785-1787, 2004 | 172 | 2004 |
| Pathobiological mechanisms underlying metabolic syndrome (MetS) in chronic obstructive pulmonary disease (COPD): clinical significance and therapeutic strategies SMH Chan, S Selemidis, S Bozinovski, R Vlahos Pharmacology & therapeutics 198, 160-188, 2019 | 166 | 2019 |
| Activation of PPARα ameliorates hepatic insulin resistance and steatosis in high fructose–fed mice despite increased endoplasmic reticulum stress SMH Chan, RQ Sun, XY Zeng, ZH Choong, H Wang, MJ Watt, JM Ye Diabetes 62 (6), 2095-2105, 2013 | 162 | 2013 |
| Reduced glycogen availability is associated with increased AMPKα2 activity, nuclear AMPKα2 protein abundance, and GLUT4 mRNA expression in contracting human skeletal muscle GR Steinberg, MJ Watt, SL McGee, S Chan, M Hargreaves, MA Febbraio, ... Applied Physiology, Nutrition, and Metabolism 31 (3), 302-312, 2006 | 154 | 2006 |
| Differing endoplasmic reticulum stress response to excess lipogenesis versus lipid oversupply in relation to hepatic steatosis and insulin resistance LP Ren, SMH Chan, XY Zeng, DR Laybutt, TJ Iseli, RQ Sun, EW Kraegen, ... PloS one 7 (2), e30816, 2012 | 129 | 2012 |
| Contraction-induced interleukin-6 gene transcription in skeletal muscle is regulated by c-Jun terminal kinase/activator protein-1 M Whitham, MHS Chan, M Pal, VB Matthews, O Prelovsek, S Lunke, ... Journal of Biological Chemistry 287 (14), 10771-10779, 2012 | 124 | 2012 |
| β‐adrenergic stimulation of skeletal muscle HSL can be overridden by AMPK signaling MJ Watt, GR Steinberg, S Chan, A Garnham, BE Kemp, MA Febbraio The FASEB journal 18 (12), 1445-1446, 2004 | 116 | 2004 |
| Screening for the efficacy on lipid accumulation in 3T3-L1 cells is an effective tool for the identification of new anti-diabetic compounds XY Zeng, X Zhou, J Xu, SMH Chan, CL Xue, JC Molero, JM Ye Biochemical pharmacology 84 (6), 830-837, 2012 | 59 | 2012 |
| Cigarette smoking exacerbates skeletal muscle injury without compromising its regenerative capacity SMH Chan, C Cerni, S Passey, HJ Seow, I Bernardo, C van der Poel, ... American Journal of Respiratory Cell and Molecular Biology 62 (2), 217-230, 2020 | 58 | 2020 |
| System-L amino acid transporters play a key role in pancreatic β-cell signalling and function Q Cheng, VD Beltran, SMH Chan, JR Brown, A Bevington, TP Herbert Journal of molecular endocrinology 56 (3), 175-187, 2016 | 52 | 2016 |
| Increasing leucine concentration stimulates mechanistic target of rapamycin signaling and cell growth in C2C12 skeletal muscle cells JL Areta, JA Hawley, JM Ye, MHS Chan, VG Coffey Nutrition research 34 (11), 1000-1007, 2014 | 47 | 2014 |
| Strategies for the discovery and development of anti-diabetic drugs from the natural products of traditional medicines JM Ye, MH Stanley Journal of Pharmacy & Pharmaceutical Sciences 16 (2), 207-216, 2013 | 38 | 2013 |
| Endoplasmic reticulum stress up‐regulates Nedd4‐2 to induce autophagy H Wang, RQ Sun, D Camera, XY Zeng, E Jo, SMH Chan, TP Herbert, ... The FASEB Journal 30 (7), 2549-2556, 2016 | 37 | 2016 |
| Neonatal overfeeding attenuates acute central pro-inflammatory effects of short-term high fat diet G Cai, T Dinan, JM Barwood, SN De Luca, A Soch, I Ziko, SMH Chan, ... Frontiers in neuroscience 8, 446, 2015 | 35 | 2015 |
| IRE1 impairs insulin signaling transduction of fructose-fed mice via JNK independent of excess lipid RQ Sun, H Wang, XY Zeng, SMH Chan, SP Li, E Jo, SL Leung, JC Molero, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (1), 156-165, 2015 | 35 | 2015 |
Bente Klarlund PedersenRigshospitaletVerified email at rh.dk