| High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, ... Cell 163 (6), 1515-1526, 2015 | 1713 | 2015 |
| Wnt signaling in development and tissue homeostasis Z Steinhart, S Angers Development 145 (11), dev146589, 2018 | 809 | 2018 |
| Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors Z Steinhart, Z Pavlovic, M Chandrashekhar, T Hart, X Wang, X Zhang, ... Nature medicine 23 (1), 60-68, 2017 | 326 | 2017 |
| Test performance evaluation of SARS-CoV-2 serological assays JD Whitman, J Hiatt, CT Mowery, BR Shy, R Yu, TN Yamamoto, U Rathore, ... Nature biotechnology 38 (10), 1174, 2020 | 270 | 2020 |
| Evaluation of SARS-CoV-2 serology assays reveals a range of test performance JD Whitman, J Hiatt, CT Mowery, BR Shy, R Yu, TN Yamamoto, U Rathore, ... Nature biotechnology 38 (10), 1174-1183, 2020 | 263 | 2020 |
| Genome-wide CRISPR-Cas9 screens expose genetic vulnerabilities and mechanisms of temozolomide sensitivity in glioblastoma stem cells G MacLeod, DA Bozek, N Rajakulendran, V Monteiro, M Ahmadi, ... Cell reports 27 (3), 971-986. e9, 2019 | 229 | 2019 |
| CRISPR activation and interference screens decode stimulation responses in primary human T cells R Schmidt, Z Steinhart, M Layeghi, JW Freimer, R Bueno, VQ Nguyen, ... Science 375 (6580), eabj4008, 2022 | 187 | 2022 |
| Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer L Aubert, N Nandagopal, Z Steinhart, G Lavoie, S Nourreddine, J Berman, ... Nature communications 11 (1), 3701, 2020 | 180 | 2020 |
| Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice Y Tao, M Mis, L Blazer, M Ustav, Z Steinhart, R Chidiac, E Kubarakos, ... Elife 8, e46134, 2019 | 93 | 2019 |
| Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay MV Gammons, TJ Rutherford, Z Steinhart, S Angers, M Bienz Journal of cell science 129 (20), 3892-3902, 2016 | 91 | 2016 |
| Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins I Cervenka, J Valnohova, O Bernatik, J Harnos, M Radsetoulal, K Sedova, ... Proceedings of the National Academy of Sciences 113 (33), 9304-9309, 2016 | 81 | 2016 |
| Single-molecule dynamics of Dishevelled at the plasma membrane and Wnt pathway activation W Ma, M Chen, H Kang, Z Steinhart, S Angers, X He, MW Kirschner Proceedings of the National Academy of Sciences 117 (28), 16690-16701, 2020 | 65 | 2020 |
| A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties Z Pavlovic, JJ Adams, LL Blazer, AK Gakhal, N Jarvik, Z Steinhart, ... MAbs 10 (8), 1157-1167, 2018 | 57 | 2018 |
| An evolved AAV variant enables efficient genetic engineering of murine T cells WA Nyberg, J Ark, A To, S Clouden, G Reeder, JJ Muldoon, JY Chung, ... Cell 186 (2), 446-460. e19, 2023 | 49 | 2023 |
| IPO11 mediates βcatenin nuclear import in a subset of colorectal cancers M Mis, S O’Brien, Z Steinhart, S Lin, T Hart, J Moffat, S Angers Journal of Cell Biology 219 (2), e201903017, 2019 | 41 | 2019 |
| Corrigendum: Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors Z Steinhart, Z Pavlovic, M Chandrashekhar, T Hart, X Wang, X Zhang, ... Nature medicine 23 (11), 1384, 2017 | 10 | 2017 |
| Bidirectional epigenetic editing reveals hierarchies in gene regulation NM Pacalin, Z Steinhart, Q Shi, JA Belk, D Dorovskyi, K Kraft, KR Parker, ... Nature Biotechnology, 1-14, 2024 | 9 | 2024 |
| SCFFBXW7 regulates G2‐M progression through control of CCNL1 ubiquitination S O'Brien, S Kelso, Z Steinhart, S Orlicky, M Mis, Y Kim, S Lin, F Sicheri, ... EMBO reports 23 (12), e55044, 2022 | 9 | 2022 |
| CRISPR activation and interference screens in primary human T cells decode cytokine regulation R Schmidt, Z Steinhart, M Layeghi, JW Freimer, VQ Nguyen, F Blaeschke, ... bioRxiv, 2021.05. 11.443701, 2021 | 8 | 2021 |
| Systematic decoding of cis gene regulation defines context-dependent control of the multi-gene costimulatory receptor locus in human T cells CT Mowery, JW Freimer, Z Chen, S Casaní-Galdón, JM Umhoefer, ... Nature Genetics, 1-12, 2024 | 5 | 2024 |
