The role of functional excipients in solid oral dosage forms to overcome poor drug dissolution and bioavailability J Van der Merwe, J Steenekamp, D Steyn, J Hamman Pharmaceutics 12 (5), 393, 2020 | 189 | 2020 |
Drug bioavailability enhancing agents of natural origin (bioenhancers) that modulate drug membrane permeation and pre-systemic metabolism B Peterson, M Weyers, JH Steenekamp, JD Steyn, C Gouws, JH Hamman Pharmaceutics 11 (1), 33, 2019 | 104 | 2019 |
Herbal hepatotoxicity: current status, examples, and challenges C Calitz, L Du Plessis, C Gouws, D Steyn, J Steenekamp, C Muller, ... Expert opinion on drug metabolism & toxicology 11 (10), 1551-1565, 2015 | 62 | 2015 |
Absorption of the novel artemisinin derivatives artemisone and artemiside: potential application of Pheroid™ technology JD Steyn, L Wiesner, LH Du Plessis, AF Grobler, PJ Smith, WC Chan, ... International journal of pharmaceutics 414 (1-2), 260-266, 2011 | 51 | 2011 |
Combination therapy of Western drugs and herbal medicines: recent advances in understanding interactions involving metabolism and efflux C Gouws, D Steyn, L Du Plessis, J Steenekamp, JH Hamman Expert opinion on drug metabolism & toxicology 8 (8), 973-984, 2012 | 48 | 2012 |
Beneficial pharmacokinetic drug interactions: a tool to improve the bioavailability of poorly permeable drugs W Gerber, JD Steyn, AF Kotzé, JH Hamman Pharmaceutics 10 (3), 106, 2018 | 47 | 2018 |
Nasal delivery of recombinant human growth hormone: in vivo evaluation with Pheroid™ technology and N-trimethyl chitosan chloride D Steyn, LH du Plessis, A Kotzé Journal of Pharmacy & Pharmaceutical Sciences 13 (2), 263-273, 2010 | 34 | 2010 |
Excipient-drug pharmacokinetic interactions: Effect of disintegrants on efflux across excised pig intestinal tissues W Gerber, JH Hamman, JD Steyn Journal of food and drug analysis 26 (2), S115-S124, 2018 | 32 | 2018 |
Capsaicin and piperine as functional excipients for improved drug delivery across nasal epithelial models W Gerber, D Steyn, A Kotzé, H Svitina, C Weldon, J Hamman Planta medica 85 (13), 1114-1123, 2019 | 18 | 2019 |
In vitro oral drug permeation models: the importance of taking physiological and physico-chemical factors into consideration R Joubert, JD Steyn, HJ Heystek, JH Steenekamp, JL Du Preez, ... Expert opinion on drug delivery 14 (2), 179-187, 2017 | 18 | 2017 |
Impact of traditional African medicine on drug metabolism and transport C Calitz, JH Steenekamp, JD Steyn, C Gouws, JM Viljoen, JH Hamman Expert opinion on drug metabolism & toxicology 10 (7), 991-1003, 2014 | 15 | 2014 |
Drug bioavailability enhancing agents of natural origin (bioenhancers) that modulate drug membrane permeation and pre-systemic metabolism. Pharmaceutics 11 B Peterson, M Weyers, JH Steenekamp, JD Steyn, C Gouws, JH Hamman Chapter, 2019 | 14 | 2019 |
Comparison of RPMI 2650 cell layers and excised sheep nasal epithelial tissues in terms of nasal drug delivery and immunocytochemistry properties W Gerber, H Svitina, D Steyn, B Peterson, A Kotzé, C Weldon, ... Journal of Pharmacological and Toxicological Methods 113, 107131, 2022 | 13 | 2022 |
Novel non-invasive protein and peptide drug delivery approaches L Wallis, E Kleynhans, TD Toit, C Gouws, D Steyn, J Steenekamp, ... Protein and Peptide Letters 21 (11), 1087-1101, 2014 | 12 | 2014 |
Evaluating in vitro cytotoxic effects of Artemisia afra and Artemisia annua infusions against selected lung cancer cell lines S van Loggenberg, C Willers, F van der Kooy, C Gouws, JH Hamman, ... South African Journal of Botany 150, 404-411, 2022 | 10 | 2022 |
Development and evaluation of a double-phase multiple-unit dosage form for enhanced insulin intestinal delivery S De Bruyn, C Willers, D Steyn, J Steenekamp, J Hamman Drug Delivery Letters 8 (1), 52-60, 2018 | 10 | 2018 |
Evaluation of isolated fractions of Aloe vera gel materials on indinavir pharmacokinetics: In vitro and in vivo studies L Wallis, M Malan, C Gouws, D Steyn, S Ellis, E Abay, L Wiesner, D P Otto, ... Current Drug Delivery 13 (3), 471-480, 2016 | 10 | 2016 |
In vitro wound healing effects of combinations of Aloe vera gel with different extracts of Bulbine frutescens A Hattingh, JP Laux, C Willers, J Hamman, D Steyn, H Hamman South African Journal of Botany 158, 254-264, 2023 | 8 | 2023 |
The in vitro and in vivo effects of Hypoxis hemerocallidea on indinavir pharmacokinetics: modulation of efflux K Havenga, E Abay, L Wiesner, A Viljoen, D Steyn, J Hamman Planta Medica 84 (12/13), 895-901, 2018 | 8 | 2018 |
Intranasal Insulin Delivery: Microparticle Formulations Consisting of Aloe vera Polysaccharides for Advanced Delivery across Excised Olfactory and Respiratory … C Kirby-Smith, J Steenekamp, D Steyn, A Haasbroek-Pheiffer, H Hamman, ... Applied Sciences 13 (8), 4822, 2023 | 6 | 2023 |