| The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway J Ninomiya-Tsuji, K Kishimoto, A Hiyama, J Inoue, Z Cao, K Matsumoto Nature 398 (6724), 252-256, 1999 | 1515 | 1999 |
| Essential function for the kinase TAK1 in innate and adaptive immune responses S Sato, H Sanjo, K Takeda, J Ninomiya-Tsuji, M Yamamoto, T Kawai, ... Nature immunology 6 (11), 1087-1095, 2005 | 1167 | 2005 |
| The TAK1–NLK–MAPK-related pathway antagonizes signalling between β-catenin and transcription factor TCF T Ishitani, J Ninomiya-Tsuji, S Nagai, M Nishita, M Meneghini, N Barker, ... Nature 399 (6738), 798-802, 1999 | 806 | 1999 |
| TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway G Takaesu, S Kishida, A Hiyama, K Yamaguchi, H Shibuya, K Irie, ... Molecular cell 5 (4), 649-658, 2000 | 776 | 2000 |
| The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca2+ pathway to antagonize Wnt/β-catenin signaling T Ishitani, S Kishida, J Hyodo-Miura, N Ueno, J Yasuda, M Waterman, ... Molecular and cellular biology, 2003 | 769 | 2003 |
| Involvement of the p38 mitogen-activated protein kinase pathway in transforming growth factor-β-induced gene expression H Hanafusa, J Ninomiya-Tsuji, N Masuyama, M Nishita, J Fujisawa, ... Journal of Biological Chemistry 274 (38), 27161-27167, 1999 | 609 | 1999 |
| XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1–TAK1 in the BMP signaling pathway K Yamaguchi, S Nagai, J Ninomiya‐Tsuji, M Nishita, K Tamai, K Irie, ... The EMBO journal, 1999 | 531 | 1999 |
| TAK1 is critical for IκB kinase-mediated activation of the NF-κB pathway G Takaesu, RM Surabhi, KJ Park, J Ninomiya-Tsuji, K Matsumoto, ... Journal of molecular biology 326 (1), 105-115, 2003 | 514 | 2003 |
| A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase J Ninomiya-Tsuji, T Kajino, K Ono, T Ohtomo, M Matsumoto, M Shiina, ... Journal of Biological Chemistry 278 (20), 18485-18490, 2003 | 466 | 2003 |
| Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol Z Jiang, J Ninomiya-Tsuji, Y Qian, K Matsumoto, X Li Molecular and cellular biology, 2002 | 387 | 2002 |
| Receptor activator of NF-κB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6 J Mizukami, G Takaesu, H Akatsuka, H Sakurai, J Ninomiya-Tsuji, ... Molecular and cellular biology 22 (4), 992-1000, 2002 | 354 | 2002 |
| MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans MD Meneghini, T Ishitani, JC Carter, N Hisamoto, J Ninomiya-Tsuji, ... Nature 399 (6738), 793-797, 1999 | 346 | 1999 |
| Role of the TAB2‐related protein TAB3 in IL‐1 and TNF signaling T Ishitani, G Takaesu, J Ninomiya‐Tsuji, H Shibuya, RB Gaynor, ... The EMBO journal, 2003 | 334 | 2003 |
| TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop K Kishimoto, K Matsumoto, J Ninomiya-Tsuji Journal of Biological Chemistry 275 (10), 7359-7364, 2000 | 334 | 2000 |
| IL-2 and EGF receptors stimulate the hematopoietic cell cycle via different signaling pathways: demonstration of a novel role for c-myc H Shibuya, M Yoneyama, J Ninomiya-Tsuji, K Matsumoto, T Taniguchi Cell 70 (1), 57-67, 1992 | 298 | 1992 |
| AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart J Li, EJ Miller, J Ninomiya-Tsuji, RR Russell III, LH Young Circulation research 97 (9), 872-879, 2005 | 293 | 2005 |
| IRAK-mediated translocation of TRAF6 and TAB2 in the interleukin-1-induced activation of NFκB Y Qian, M Commane, J Ninomiya-Tsuji, K Matsumoto, X Li Journal of Biological Chemistry 276 (45), 41661-41667, 2001 | 288 | 2001 |
| TAK1 control of cell death SR Mihaly, J Ninomiya-Tsuji, S Morioka Cell Death & Differentiation 21 (11), 1667-1676, 2014 | 286 | 2014 |
| Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/β-catenin signaling T Ishitani, J Ninomiya-Tsuji, K Matsumoto Molecular and cellular biology, 2003 | 282 | 2003 |
| Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway G Takaesu, J Ninomiya-Tsuji, S Kishida, X Li, GR Stark, K Matsumoto Molecular and cellular biology, 2001 | 265 | 2001 |