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Roger Mulet Lazaro
Roger Mulet Lazaro
Postdoctoral researcher, Erasmus Medical Center
Verified email at erasmusmc.nl
Title
Cited by
Cited by
Year
CEBPA mutations in 4708 patients with acute myeloid leukemia: differential impact of bZIP and TAD mutations on outcome
F Taube, JA Georgi, M Kramer, S Stasik, JM Middeke, C Röllig, U Krug, ...
Blood, The Journal of the American Society of Hematology 139 (1), 87-103, 2022
1232022
Atypical 3q26/MECOM rearrangements genocopy inv(3)/t(3;3) in acute myeloid leukemia
S Ottema, R Mulet-Lazaro, HB Beverloo, C Erpelinck, S van Herk, ...
Blood, The Journal of the American Society of Hematology 136 (2), 224-234, 2020
612020
The leukemic oncogene EVI1 hijacks a MYC super-enhancer by CTCF-facilitated loops
S Ottema, R Mulet-Lazaro, C Erpelinck-Verschueren, S van Herk, ...
Nature Communications 12 (1), 5679, 2021
472021
PopHuman: the human population genomics browser
S Casillas, R Mulet, P Villegas-Miron, S Hervas, E Sanz, D Velasco, ...
Nucleic acids research 46 (D1), D1003-D1010, 2018
442018
Novel neuroprotective multicomponent therapy for amyotrophic lateral sclerosis designed by networked systems
M Herrando-Grabulosa, R Mulet, A Pujol, JM Mas, X Navarro, P Aloy, ...
PLoS One 11 (1), e0147626, 2016
392016
Selective requirement of MYB for oncogenic hyperactivation of a translocated enhancer in leukemia
L Smeenk, S Ottema, R Mulet-Lazaro, A Ebert, M Havermans, AA Varea, ...
Cancer discovery 11 (11), 2868-2883, 2021
342021
Allele-specific expression of GATA2 due to epigenetic dysregulation in CEBPA double-mutant AML
R Mulet-Lazaro, S van Herk, C Erpelinck, E Bindels, MA Sanders, ...
Blood, The Journal of the American Society of Hematology 138 (2), 160-177, 2021
222021
Aberrant EVI1 splicing contributes to EVI1-rearranged leukemia
A Tanaka, TA Nakano, M Nomura, H Yamazaki, JP Bewersdorf, ...
Blood, The Journal of the American Society of Hematology 140 (8), 875-888, 2022
172022
Systems biology applied to non-alcoholic fatty liver disease (NAFLD): treatment selection based on the mechanism of action of nutraceuticals
S Perera, L Artigas, R Mulet, JM Mas, T Sardón
Nutrafoods 13, 61-68, 2014
132014
From Genotype to Phenotype: How Enhancers Control Gene Expression and Cell Identity in Hematopoiesis
R Mulet-Lazaro, R Delwel
HemaSphere 7 (11), e969, 2023
72023
Induced cell-autonomous neutropenia systemically perturbs hematopoiesis in Cebpa enhancer-null mice
R Avellino, R Mulet-Lazaro, M Havermans, R Hoogenboezem, L Smeenk, ...
Blood advances 6 (5), 1406-1419, 2022
72022
STAG2 mutations reshape the cohesin-structured spatial chromatin architecture to drive gene regulation in acute myeloid leukemia
A Fischer, B Hernández-Rodríguez, R Mulet-Lazaro, M Nuetzel, F Hölzl, ...
Cell Reports 43 (8), 2024
62024
Oncogene EVI1 drives acute myeloid leukemia via a targetable interaction with CTBP2
D Pastoors, M Havermans, R Mulet-Lazaro, D Brian, W Noort, J Grasel, ...
Science Advances 10 (20), eadk9076, 2024
62024
Cellular and metabolic characteristics of pre-leukemic hematopoietic progenitors with GATA2 haploinsufficiency
A Rein, I Geron, E Kugler, H Fishman, E Gottlieb, I Abramovich, A Giladi, ...
Haematologica 108 (9), 2316, 2022
62022
Oncogenic enhancers in leukemia
R Mulet-Lazaro, R Delwel
Blood Cancer Discovery 5 (5), 303-317, 2024
32024
Aberrant DNA methylation patterns in microsatellite stable human colorectal cancers define a new marker panel for the CpG island methylator phenotype
C Gebhard, R Mulet-Lazaro, D Glatz, L Schwarzfischer-Pfeilschifter, ...
International journal of cancer, 2021
32021
Epigenetic alterations affecting hematopoietic regulatory networks as drivers of mixed myeloid/lymphoid leukemia
R Mulet-Lazaro, S van Herk, M Nuetzel, A Sijs-Szabo, N Díaz, K Kelly, ...
Nature Communications 15 (1), 5693, 2024
22024
Complex 3q26/EVI1 Rearrangements Genocopy Inv (3)/t (3; 3) Acute Myeloid Leukemias By Enhancer Hijacking, EVI1 Overexpression, Absent MDS1-EVI1 and Low GATA2 Expression
S Ottema, R Mulet-Lazaro, B Beverloo, M Havermans, ...
Blood 132, 2766, 2018
12018
A Novel XACT lncRNA Transcript with Functions Transcending X-Chromosome Inactivation.
P Zhang, PH Angles, H Zhang, T Li, R Mulet-Lazaro, WFJ van IJcken, ...
bioRxiv, 2025.01. 03.631201, 2025
2025
MECOM is a master repressor of myeloid differentiation through dose control of CEBPA in acute myeloid leukemia
D Pastoors, M Havermans, R Mulet-Lazaro, L Smeenk, S Ottema, ...
bioRxiv, 2025.01. 02.631046, 2025
2025
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