Targeting ER stress–induced autophagy overcomes BRAF inhibitor resistance in melanoma XH Ma, SF Piao, S Dey, Q Mcafee, G Karakousis, J Villanueva, LS Hart, ... The Journal of clinical investigation 124 (3), 1406-1417, 2014 | 486 | 2014 |
Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency Q McAfee, Z Zhang, A Samanta, SM Levi, XH Ma, S Piao, JP Lynch, ... Proceedings of the National Academy of Sciences 109 (21), 8253-8258, 2012 | 442 | 2012 |
A unified approach to targeting the lysosome's degradative and growth signaling roles VW Rebecca, MC Nicastri, N McLaughlin, C Fennelly, Q McAfee, ... Cancer discovery 7 (11), 1266-1283, 2017 | 178 | 2017 |
Autophagy gene Atg16L1 prevents lethal T cell alloreactivity mediated by dendritic cells VM Hubbard-Lucey, Y Shono, K Maurer, ML West, NV Singer, ... Immunity 41 (4), 579-591, 2014 | 109 | 2014 |
Highly selective β-mannosylations and β-rhamnosylations catalyzed by bis-thiourea Q Li, SM Levi, EN Jacobsen Journal of the American Chemical Society 142 (27), 11865-11872, 2020 | 85 | 2020 |
Site-selective, stereocontrolled glycosylation of minimally protected sugars Q Li, SM Levi, CC Wagen, AE Wendlandt, EN Jacobsen Nature 608 (7921), 74-79, 2022 | 72 | 2022 |
Autophagy inhibition enhances sunitinib efficacy in clear cell ovarian carcinoma L DeVorkin, M Hattersley, P Kim, J Ries, J Spowart, MS Anglesio, SM Levi, ... Molecular Cancer Research 15 (3), 250-258, 2017 | 72 | 2017 |
Catalytic activation of glycosyl phosphates for stereoselective coupling reactions SM Levi, Q Li, AR Rötheli, EN Jacobsen Proceedings of the National Academy of Sciences 116 (1), 35-39, 2019 | 69 | 2019 |
Palladium-catalyzed C− CN activation for intramolecular cyanoesterification of alkynes NR Rondla, SM Levi, JM Ryss, RA Vanden Berg, CJ Douglas Organic Letters 13 (8), 1940-1943, 2011 | 60 | 2011 |
Discovery of diaminopyrimidine carboxamide HPK1 inhibitors as preclinical immunotherapy tool compounds BA Vara, SM Levi, A Achab, DA Candito, X Fradera, CA Lesburg, ... ACS Medicinal Chemistry Letters 12 (4), 653-661, 2021 | 41 | 2021 |
Reductive sp3–sp2 Coupling Reactions Enable Late-Stage Modification of Pharmaceuticals KM Mennie, BA Vara, SM Levi Organic letters 22 (2), 556-559, 2020 | 20 | 2020 |
Unifying catalysis framework to dissect proteasomal degradation paradigms FP Rodriguez-Rivera, SM Levi ACS Central Science 7 (7), 1117-1125, 2021 | 18 | 2021 |
Catalyst‐Controlled Glycosylation SM Levi, EN Jacobsen* Organic Reactions, 801-852, 2004 | 16 | 2004 |
Diaminopyrimidine carboxamide inhibitors of hpk1 A Achab, DA Candito, A Donofrio, X Fradera, S Kawamura, SM Levi, B Li, ... US Patent App. 18/251,259, 2023 | 1 | 2023 |
Site-Selective, Stereocontrolled Glycosylation Catalyzed by Bis-Thioureas Q Li, SM Levi, CC Wagen, AE Wendlandt, EN Jacobsen | 1 | 2022 |
Site-Selective, Stereocontrolled Glycosylation Catalyzed by Bis-Thioureas E Jacobsen, Q Li, S Levi, C Wagen, A Wendlandt | | 2022 |
Catalyst-controlled regio-and stereoselective glycosylation Q Li, S Levi, E Jacobsen ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |
Stereo-and Regioselective Glycosylation SM Levi Harvard University, 2019 | | 2019 |
Discovery of a novel series of aminopyrazine-based A2a antagonists for the treatment of Parkinson's disease: Integration of an intramolecular H-bonding strategy in the design … R Kuang, H Wu, A Ali, P Ting, S Levi, M Lo, E Metzger, T Henderson, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016 | | 2016 |
The Design and Synthesis of Chloroquine Derivatives to Block Autophagy in Cancer Cells SM Levi University of Pennsylvania, 2014 | | 2014 |