| Regulation of microRNA function in animals LFR Gebert, IJ MacRae Nature reviews Molecular cell biology 20 (1), 21-37, 2019 | 2183 | 2019 |
| Structural basis for double-stranded RNA processing by Dicer IJ MacRae, K Zhou, F Li, A Repic, AN Brooks, WZ Cande, PD Adams, ... Science 311 (5758), 195-198, 2006 | 1350 | 2006 |
| The RNA-induced silencing complex: a versatile gene-silencing machine AJ Pratt, IJ MacRae Journal of Biological Chemistry 284 (27), 17897-17901, 2009 | 936 | 2009 |
| The crystal structure of human Argonaute2 NT Schirle, IJ MacRae Science 336 (6084), 1037-1040, 2012 | 847 | 2012 |
| Structural basis for microRNA targeting NT Schirle, J Sheu-Gruttadauria, IJ MacRae Science 346 (6209), 608-613, 2014 | 650 | 2014 |
| In vitro reconstitution of the human RISC-loading complex IJ MacRae, E Ma, M Zhou, CV Robinson, JA Doudna Proceedings of the National Academy of Sciences 105 (2), 512-517, 2008 | 628 | 2008 |
| Structural determinants of RNA recognition and cleavage by Dicer IJ MacRae, K Zhou, JA Doudna Nature structural & molecular biology 14 (10), 934-940, 2007 | 425 | 2007 |
| Ribonuclease revisited: structural insights into ribonuclease III family enzymes IJ MacRae, JA Doudna Current opinion in structural biology 17 (1), 138-145, 2007 | 334 | 2007 |
| Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3′ to 5′ exonuclease activity essential for immune suppression KM Hastie, CR Kimberlin, MA Zandonatti, IJ MacRae, EO Saphire Proceedings of the National Academy of Sciences 108 (6), 2396-2401, 2011 | 320 | 2011 |
| The molecular architecture of human Dicer PW Lau, KZ Guiley, N De, CS Potter, B Carragher, IJ MacRae Nature structural & molecular biology 19 (4), 436-440, 2012 | 295 | 2012 |
| Autoinhibition of human dicer by its internal helicase domain E Ma, IJ MacRae, JF Kirsch, JA Doudna Journal of molecular biology 380 (1), 237-243, 2008 | 294 | 2008 |
| A dynamic search process underlies microRNA targeting SD Chandradoss, NT Schirle, M Szczepaniak, IJ MacRae, C Joo Cell 162 (1), 96-107, 2015 | 277 | 2015 |
| Phase transitions in the assembly and function of human miRISC J Sheu-Gruttadauria, IJ MacRae Cell 173 (4), 946-957. e16, 2018 | 267 | 2018 |
| Structural basis for target-directed microRNA degradation J Sheu-Gruttadauria, P Pawlica, SM Klum, S Wang, TA Yario, ... Molecular cell 75 (6), 1243-1255. e7, 2019 | 225 | 2019 |
| Akt-mediated phosphorylation of argonaute 2 downregulates cleavage and upregulates translational repression of MicroRNA targets SR Horman, MM Janas, C Litterst, B Wang, IJ MacRae, MJ Sever, ... Molecular cell 50 (3), 356-367, 2013 | 194 | 2013 |
| COMRADES determines in vivo RNA structures and interactions O Ziv, MM Gabryelska, ATL Lun, LFR Gebert, J Sheu-Gruttadauria, ... Nature methods 15 (10), 785-788, 2018 | 180 | 2018 |
| Structural foundations of RNA silencing by Argonaute J Sheu-Gruttadauria, IJ MacRae Journal of molecular biology 429 (17), 2619-2639, 2017 | 178 | 2017 |
| Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression CR Kimberlin, ZA Bornholdt, S Li, VL Woods Jr, IJ MacRae, EO Saphire Proceedings of the National Academy of Sciences 107 (1), 314-319, 2010 | 161 | 2010 |
| Highly complementary target RNAs promote release of guide RNAs from human Argonaute2 N De, L Young, PW Lau, NC Meisner, DV Morrissey, IJ MacRae Molecular cell 50 (3), 344-355, 2013 | 156 | 2013 |
| Structure of Dicer and mechanistic implications for RNAi IJ Macrae, F Li, K Zhou, WZ Cande, JA Doudna Cold Spring Harbor symposia on quantitative biology 71, 73-80, 2006 | 151 | 2006 |