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Michelle Sargent
Michelle Sargent
Laboratory Manager
Verified email at cchmc.org
Title
Cited by
Cited by
Year
Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart
X Fu, H Khalil, O Kanisicak, JG Boyer, RJ Vagnozzi, BD Maliken, ...
The Journal of clinical investigation 128 (5), 2127-2143, 2018
5832018
Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling
T Oka, J Xu, RA Kaiser, J Melendez, M Hambleton, MA Sargent, A Lorts, ...
Circulation research 101 (3), 313-321, 2007
5682007
An acute immune response underlies the benefit of cardiac stem cell therapy
RJ Vagnozzi, M Maillet, MA Sargent, H Khalil, AKZ Johansen, ...
Nature 577 (7790), 405-409, 2020
5212020
Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy
DP Millay, MA Sargent, H Osinska, CP Baines, ER Barton, G Vuagniaux, ...
Nature medicine 14 (4), 442-447, 2008
4252008
The mitochondrial calcium uniporter selectively matches metabolic output to acute contractile stress in the heart
JQ Kwong, X Lu, RN Correll, JA Schwanekamp, RJ Vagnozzi, MA Sargent, ...
Cell reports 12 (1), 15-22, 2015
3792015
Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice
J Karch, JQ Kwong, AR Burr, MA Sargent, JW Elrod, PM Peixoto, ...
elife 2, e00772, 2013
3272013
Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart
J Heineke, M Auger-Messier, J Xu, T Oka, MA Sargent, A York, R Klevitsky, ...
The Journal of clinical investigation 117 (11), 3198-3210, 2007
2962007
Genetic deletion of myostatin from the heart prevents skeletal muscle atrophy in heart failure
J Heineke, M Auger-Messier, J Xu, M Sargent, A York, S Welle, ...
Circulation 121 (3), 419-425, 2010
2952010
Fibroblast-specific genetic manipulation of p38 mitogen-activated protein kinase in vivo reveals its central regulatory role in fibrosis
JD Molkentin, D Bugg, N Ghearing, LE Dorn, P Kim, MA Sargent, ...
Circulation 136 (6), 549-561, 2017
2882017
Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism
DP Millay, SA Goonasekera, MA Sargent, M Maillet, BJ Aronow, ...
Proceedings of the National Academy of Sciences 106 (45), 19023-19028, 2009
2632009
Inhibiting fibronectin attenuates fibrosis and improves cardiac function in a model of heart failure
I Valiente-Alandi, SJ Potter, AM Salvador, AE Schafer, T Schips, ...
Circulation 138 (12), 1236-1252, 2018
2612018
Cardiac myosin binding protein C phosphorylation is cardioprotective
S Sadayappan, H Osinska, R Klevitsky, JN Lorenz, M Sargent, ...
Proceedings of the National Academy of Sciences 103 (45), 16918-16923, 2006
2502006
A thrombospondin-dependent pathway for a protective ER stress response
JM Lynch, M Maillet, D Vanhoutte, A Schloemer, MA Sargent, NS Blair, ...
Cell 149 (6), 1257-1268, 2012
2392012
Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle
SA Goonasekera, CK Lam, DP Millay, MA Sargent, RJ Hajjar, EG Kranias, ...
The Journal of clinical investigation 121 (3), 1044-1052, 2011
2322011
Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD
J Karch, MJ Bround, H Khalil, MA Sargent, N Latchman, N Terada, ...
Science advances 5 (8), eaaw4597, 2019
2182019
DUSP6 (MKP3) null mice show enhanced ERK1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibility
M Maillet, NH Purcell, MA Sargent, AJ York, OF Bueno, JD Molkentin
Journal of Biological Chemistry 283 (45), 31246-31255, 2008
2152008
Decreased cardiac L-type Ca2+ channel activity induces hypertrophy and heart failure in mice
SA Goonasekera, K Hammer, M Auger-Messier, I Bodi, X Chen, H Zhang, ...
The Journal of clinical investigation 122 (1), 280-290, 2012
2052012
Genetic deletion of the mitochondrial phosphate carrier desensitizes the mitochondrial permeability transition pore and causes cardiomyopathy
JQ Kwong, J Davis, CP Baines, MA Sargent, J Karch, X Wang, T Huang, ...
Cell Death & Differentiation 21 (8), 1209-1217, 2014
1912014
Genetic manipulation of periostin expression in the heart does not affect myocyte content, cell cycle activity, or cardiac repair
A Lorts, JA Schwanekamp, JW Elrod, MA Sargent, JD Molkentin
Circulation research 104 (1), e1-e7, 2009
1362009
Age-dependent effect of myostatin blockade on disease severity in a murine model of limb-girdle muscular dystrophy
SA Parsons, DP Millay, MA Sargent, EM McNally, JD Molkentin
The American journal of pathology 168 (6), 1975-1985, 2006
1282006
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