Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases M Iwashima, BA Irving, NSC Van Oers, AC Chan, A Weiss Science 263 (5150), 1136-1139, 1994 | 964 | 1994 |
Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes. NS Van Oers, N Killeen, A Weiss The Journal of experimental medicine 183 (3), 1053-1062, 1996 | 422 | 1996 |
αβ T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases NSC Van Oers, B Lowin-Kropf, D Finlay, K Connolly, A Weiss Immunity 5 (5), 429-436, 1996 | 399 | 1996 |
ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR ζ in murine thymocytes and lymph node T cells NSC van Oers, N Killeen, A Welss Immunity 1 (8), 675-685, 1994 | 323 | 1994 |
Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling. AC Chan, NS Van Oers, A Tran, L Turka, CL Law, JC Ryan, EA Clark, ... The Journal of Immunology 152 (10), 4758-4766, 1994 | 312 | 1994 |
T-cell receptor signal transmission: who gives an ITAM? LA Pitcher, NSC Van Oers Trends in immunology 24 (10), 554-560, 2003 | 271 | 2003 |
The antibiotic resistance arrow of time: efflux pump induction is a general first step in the evolution of mycobacterial drug resistance AM Schmalstieg, S Srivastava, S Belkaya, D Deshpande, C Meek, R Leff, ... Antimicrobial agents and chemotherapy 56 (9), 4806-4815, 2012 | 211 | 2012 |
Tetracycline-controllable Selection of CD4+ T Cells: Half-Life and Survival Signals in the Absence of Major Histocompatibility Complex Class II Molecules D Witherden, N Van Oers, C Waltzinger, A Weiss, C Benoist, D Mathis The Journal of experimental medicine 191 (2), 355-364, 2000 | 210 | 2000 |
Scalable signaling mediated by T cell antigen receptor–CD3 ITAMs ensures effective negative selection and prevents autoimmunity J Holst, H Wang, KD Eder, CJ Workman, KL Boyd, Z Baquet, H Singh, ... Nature immunology 9 (6), 658-666, 2008 | 178 | 2008 |
Differential requirements for ZAP-70 in TCR signaling and T cell development TA Kadlecek, NSC Van Oers, L Lefrancois, S Olson, D Finlay, DH Chu, ... The Journal of Immunology 161 (9), 4688-4694, 1998 | 160 | 1998 |
The pre-T cell receptor (TCR) complex is functionally coupled to the TCR-zeta subunit. NS Van Oers, H Von Boehmer, A Weiss The Journal of experimental medicine 182 (5), 1585-1590, 1995 | 141 | 1995 |
Constitutive tyrosine phosphorylation of the T-cell receptor (TCR) zeta subunit: regulation of TCR-associated protein tyrosine kinase activity by TCR zeta NS Van Oers, W Tao, JD Watts, P Johnson, R Aebersold, HS Teh Molecular and Cellular Biology 13 (9), 5771-5780, 1993 | 137 | 1993 |
The genetics and epigenetics of 22q11. 2 deletion syndrome Q Du, MT de la Morena, NSC van Oers Frontiers in genetics, 1365, 2020 | 122 | 2020 |
The 21-and 23-kD forms of TCRζ are generated by specific ITAM phosphorylations NSC Van Oers, B Tohlen, B Malissen, CR Moomaw, S Afendis, ... Nature immunology 1 (4), 322-328, 2000 | 121 | 2000 |
T cell receptor (TCR) clustering in the immunological synapse integrates TCR and costimulatory signaling in selected T cells B Purtic, LA Pitcher, NSC Van Oers, C Wülfing Proceedings of the National Academy of Sciences 102 (8), 2904-2909, 2005 | 120 | 2005 |
The Syk/ZAP-70 protein tyrosine kinase connection to antigen receptor signalling processes NSC van Oers, A Weiss Seminars in immunology 7 (4), 227-236, 1995 | 117 | 1995 |
Deletion of antigen-specific immature thymocytes by dendritic cells requires LFA-1/ICAM interactions. DA Carlow, NS Van Oers, SJ Teh, HS Teh The Journal of Immunology 148 (6), 1595-1603, 1992 | 108 | 1992 |
The CD3 ζ Subunit Contains a Phosphoinositide-Binding Motif That Is Required for the Stable Accumulation of TCR–CD3 Complex at the Immunological Synapse LM DeFord-Watts, DS Dougall, S Belkaya, BA Johnson, JL Eitson, ... The Journal of Immunology 186 (12), 6839-6847, 2011 | 98 | 2011 |
Spatiotemporal patterning during T cell activation is highly diverse KL Singleton, KT Roybal, Y Sun, G Fu, NRJ Gascoigne, NSC Van Oers, ... Science signaling 2 (65), ra15-ra15, 2009 | 98 | 2009 |
Regulation of TCR signal transduction in murine thymocytes by multiple TCR ζ-chain signaling motifs NSC Van Oers, PE Love, EW Shores, A Weiss The Journal of Immunology 160 (1), 163-170, 1998 | 98 | 1998 |