Human gain-of-function MC4R variants show signaling bias and protect against obesity LA Lotta, J Mokrosiński, EM de Oliveira, C Li, SJ Sharp, J Luan, ... Cell 177 (3), 597-607. e9, 2019 | 271 | 2019 |
Association of genetic variants related to gluteofemoral vs abdominal fat distribution with type 2 diabetes, coronary disease, and cardiovascular risk factors LA Lotta, LBL Wittemans, V Zuber, ID Stewart, SJ Sharp, J Luan, FR Day, ... Jama 320 (24), 2553-2563, 2018 | 198 | 2018 |
Genome-wide association analysis in humans links nucleotide metabolism to leukocyte telomere length C Li, S Stoma, LA Lotta, S Warner, E Albrecht, A Allione, PP Arp, L Broer, ... The American Journal of Human Genetics 106 (3), 389-404, 2020 | 165 | 2020 |
A cross-platform approach identifies genetic regulators of human metabolism and health LA Lotta, M Pietzner, ID Stewart, LBL Wittemans, C Li, R Bonelli, J Raffler, ... Nature genetics 53 (1), 54-64, 2021 | 162 | 2021 |
A conserved role for atlastin GTPases in regulating lipid droplet size RW Klemm, JP Norton, RA Cole, CS Li, SH Park, MM Crane, L Li, D Jin, ... Cell reports 3 (5), 1465-1475, 2013 | 159 | 2013 |
A c‐Myc‐MicroRNA functional feedback loop affects hepatocarcinogenesis H Han, D Sun, W Li, H Shen, Y Zhu, C Li, Y Chen, L Lu, W Li, J Zhang, ... Hepatology 57 (6), 2378-2389, 2013 | 122 | 2013 |
Roles of acyl-CoA: diacylglycerol acyltransferases 1 and 2 in triacylglycerol synthesis and secretion in primary hepatocytes C Li, L Li, J Lian, R Watts, R Nelson, B Goodwin, R Lehner Arteriosclerosis, thrombosis, and vascular biology 35 (5), 1080-1091, 2015 | 94 | 2015 |
Rare and common genetic determinants of metabolic individuality and their effects on human health P Surendran, ID Stewart, VPW Au Yeung, M Pietzner, J Raffler, ... Nature Medicine 28 (11), 2321-2332, 2022 | 90 | 2022 |
Association of genetically enhanced lipoprotein lipase–mediated lipolysis and low-density lipoprotein cholesterol–lowering alleles with risk of coronary disease and type 2 diabetes LA Lotta, ID Stewart, SJ Sharp, FR Day, S Burgess, J Luan, N Bowker, ... JAMA cardiology 3 (10), 957-966, 2018 | 81 | 2018 |
Identification of rare loss-of-function genetic variation regulating body fat distribution M Koprulu, Y Zhao, E Wheeler, L Dong, N Rocha, C Li, JD Griffin, S Patel, ... The Journal of Clinical Endocrinology & Metabolism 107 (4), 1065-1077, 2022 | 19 | 2022 |
Building external control arms from patient-level electronic health record data to replicate the randomized IMblaze370 control arm in metastatic colorectal cancer C Schröder, M Lawrance, C Li, C Lenain, SK Mhatre, M Fakih, ... JCO Clinical Cancer Informatics 5, 450-458, 2021 | 17 | 2021 |
Cross-platform genetic discovery of small molecule products of metabolism and application to clinical outcomes LA Lotta, M Pietzner, ID Stewart, LBL Wittemans, C Li, R Bonelli, J Raffler, ... Nature genetics 53 (1), 54, 2021 | 16 | 2021 |
Hybrid-control arm construction using historical trial data for an early-phase, randomized controlled trial in metastatic colorectal cancer C Li, A Ferro, SK Mhatre, D Lu, M Lawrance, X Li, S Li, S Allen, J Desai, ... Communications Medicine 2 (1), 90, 2022 | 11 | 2022 |
Real world progression-free survival in patients with advanced or metastatic urothelial cancer treated with first-line platinum-based chemotherapy C Nikolaidis, C Li, C Lee, A Mecke, I Reyes-Rivera, C Schroder PHARMACOEPIDEMIOLOGY AND DRUG SAFETY 30, 319-319, 2021 | | 2021 |
Simulation-based evaluation of index date selection methods with external controls C Gower-Page, C Li, C Schroder, SK Mhatre, I Reyes-Rivera, C Harbron PHARMACOEPIDEMIOLOGY AND DRUG SAFETY 30, 340-341, 2021 | | 2021 |