Microfluidic droplets: new integrated workflows for biological experiments B Kintses, LD van Vliet, SRA Devenish, F Hollfelder Current opinion in chemical biology 14 (5), 548-555, 2010 | 221 | 2010 |
A fully unsupervised compartment-on-demand platform for precise nanoliter assays of time-dependent steady-state enzyme kinetics and inhibition F Gielen, L van Vliet, BT Koprowski, SRA Devenish, M Fischlechner, ... Analytical chemistry 85 (9), 4761-4769, 2013 | 111 | 2013 |
Molecular Recognition of DNA by Rigid [n]-Polynorbornane-Derived Bifunctional Intercalators: Synthesis and Evaluation of Their Binding Properties LD Van Vliet, T Ellis, PJ Foley, L Liu, FM Pfeffer, RA Russell, RN Warrener, ... Journal of medicinal chemistry 50 (10), 2326-2340, 2007 | 58 | 2007 |
Plasmodium dihydrofolate reductase is a second enzyme target for the antimalarial action of triclosan E Bilsland, L Van Vliet, K Williams, J Feltham, MP Carrasco, WL Fotoran, ... Scientific Reports 8 (1), 1-8, 2018 | 57 | 2018 |
Interfacing microwells with nanoliter compartments: a sampler generating high-resolution concentration gradients for quantitative biochemical analyses in droplets F Gielen, T Buryska, LV Vliet, M Butz, J Damborsky, Z Prokop, F Hollfelder Analytical chemistry 87 (1), 624-632, 2015 | 53 | 2015 |
Polyethylene imine derivatives (‘synzymes') accelerate phosphate transfer in the absence of metal F Avenier, JB Domingos, LD Van Vliet, F Hollfelder Journal of the American Chemical Society 129 (24), 7611-7619, 2007 | 52 | 2007 |
Investigating host-microbiome interactions by droplet based microfluidics AS Tauzin, MR Pereira, LD Van Vliet, PY Colin, E Laville, J Esque, ... Microbiome 8, 1-20, 2020 | 47 | 2020 |
Ultrahigh-Throughput Enzyme Engineering and Discovery in In Vitro Compartments M Gantz, S Neun, EJ Medcalf, LD van Vliet, F Hollfelder Chemical Reviews 123 (9), 5571-5611, 2023 | 40 | 2023 |
Long‐term perfusion culture of monoclonal embryonic stem cells in 3D hydrogel beads for continuous optical analysis of differentiation H Kleine‐Brüggeney, LD Van Vliet, C Mulas, F Gielen, CC Agley, ... Small 15 (5), 1804576, 2019 | 40 | 2019 |
The search for efficient intramolecular proton transfer from carbon: the kinetically silent intramolecular general base‐catalysed elimination reaction of O‐phenyl 8 … N Asaad, JE Davies, DRW Hodgson, AJ Kirby, L Vliet, L Ottavi Journal of physical organic chemistry 18 (2), 101-109, 2005 | 26 | 2005 |
Controlled oil/water partitioning of hydrophobic substrates extending the bioanalytical applications of droplet-based microfluidics T Buryska, M Vasina, F Gielen, P Vanacek, L van Vliet, J Jezek, Z Pilat, ... Analytical chemistry 91 (15), 10008-10015, 2019 | 24 | 2019 |
Relating chemical and biological diversity space: A tunable system for efficient gene transfection LD Van Vliet, MR Chapman, F Avenier, CZ Kitson, F Hollfelder ChemBioChem 9 (12), 1960-1967, 2008 | 18 | 2008 |
Bioinspired genotype–phenotype linkages: mimicking cellular compartmentalization for the engineering of functional proteins LD van Vliet, PY Colin, F Hollfelder Interface Focus 5 (4), 20150035, 2015 | 17 | 2015 |
High-throughput steady-state enzyme kinetics measured in a parallel droplet generation and absorbance detection platform S Neun, L van Vliet, F Hollfelder, F Gielen Analytical Chemistry 94 (48), 16701-16710, 2022 | 13 | 2022 |
A Titratable Cell Lysis-on-Demand System for Droplet-Compartmentalized Ultrahigh-Throughput Screening in Functional Metagenomics and Directed Evolution CF Alex Wong, L van Vliet, SV Bhujbal, C Guo, M Sletmoen, BT Stokke, ... ACS synthetic biology 10 (8), 1882-1894, 2021 | 9 | 2021 |
Droplet-on-Demand Platform for Biochemical Screening & Drug Discovery LD Van Vliet, F Gielen, A Sinha, BT Koprowski, JB Edel, X Niu, ... 18th International Conference on Miniaturized Systems for Chemistry and Life …, 2014 | 5 | 2014 |
Microfluidic droplets and their applications: diagnosis, drug screening and the discovery of therapeutic enzymes LD van Vliet, F Hollfelder International Conference on the Development of Biomedical Engineering in …, 2018 | 3 | 2018 |
A unified in vitro to in vivo fluorescence lifetime screening platform yields amyloid β aggregation inhibitors S Collins, L van Vliet, F Gielen, M Janeček, SW Valladolid, C Poudel, ... bioRxiv, 2022.03. 28.485913, 2022 | 2 | 2022 |
O4‐10‐03: AN ASSAY FOR SEEDED PROTEIN AGGREGATION DETECTS ABETA SEEDS IN SERUM DC Crowther, L van Vliet, S Kuhaudomlarp, F Gielen, J Yan, M Azhar, ... Alzheimer's & Dementia 10, P271-P271, 2014 | 2 | 2014 |
Identification and development of small molecule inhibitors of the aggregation of amyloid beta S Collins, F Gielen, L van Vliet, G Kaminski, F Hollfelder, D Spring ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | 1 | 2017 |