New carbapenemase inhibitors: clearing the way for the β-lactams JC Vázquez-Ucha, J Arca-Suárez, G Bou, A Beceiro International journal of molecular sciences 21 (23), 9308, 2020 | 112 | 2020 |
Analysis of the role of the LH92_11085 gene of a biofilm hyper-producing Acinetobacter baumannii strain on biofilm formation and attachment to eukaryotic cells L Álvarez-Fraga, A Pérez, S Rumbo-Feal, M Merino, JA Vallejo, ... Virulence 7 (4), 443-455, 2016 | 60 | 2016 |
Molecular mechanisms driving the in vivo development of OXA-10-mediated resistance to ceftolozane/tazobactam and ceftazidime/avibactam during treatment of XDR Pseudomonas … J Arca-Suárez, C Lasarte-Monterrubio, BK Rodiño-Janeiro, G Cabot, ... Journal of Antimicrobial Chemotherapy 76 (1), 91-100, 2021 | 52 | 2021 |
Assessment of activity and resistance mechanisms to cefepime in combination with the novel β-lactamase inhibitors zidebactam, taniborbactam, and enmetazobactam against a … JC Vázquez-Ucha, C Lasarte-Monterrubio, P Guijarro-Sánchez, M Oviaño, ... Antimicrobial Agents and Chemotherapy 66 (2), e01676-21, 2022 | 44 | 2022 |
Activity of imipenem/relebactam against a Spanish nationwide collection of carbapenemase-producing Enterobacterales JC Vázquez-Ucha, A Seoane-Estévez, BK Rodiño-Janeiro, ... Journal of Antimicrobial Chemotherapy 76 (6), 1498-1510, 2021 | 44 | 2021 |
Selection of AmpC β-lactamase variants and metallo-β-lactamases leading to ceftolozane/tazobactam and ceftazidime/avibactam resistance during treatment of MDR/XDR Pseudomonas … A Ruedas-López, I Alonso-García, C Lasarte-Monterrubio, ... Antimicrobial Agents and Chemotherapy 66 (2), e02067-21, 2022 | 43 | 2022 |
Pneumonia infection in mice reveals the involvement of the feoA gene in the pathogenesis of Acinetobacter baumannii L Álvarez-Fraga, JC Vázquez-Ucha, M Martínez-Guitián, JA Vallejo, ... Virulence 9 (1), 496-509, 2018 | 41 | 2018 |
LN-1-255, a penicillanic acid sulfone able to inhibit the class D carbapenemase OXA-48 JA Vallejo, M Martinez-Guitian, JC Vázquez-Ucha, C González-Bello, ... Journal of Antimicrobial Chemotherapy 71 (8), 2171-2180, 2016 | 39 | 2016 |
Activity of the β-lactamase inhibitor LN-1-255 against carbapenem-hydrolyzing class D β-lactamases from Acinetobacter baumannii JC Vázquez-Ucha, M Maneiro, M Martínez-Guitián, J Buynak, CR Bethel, ... Antimicrobial Agents and Chemotherapy 61 (11), 10.1128/aac. 01172-17, 2017 | 38 | 2017 |
Molecular and biochemical insights into the in vivo evolution of AmpC-mediated resistance to ceftolozane/tazobactam during treatment of an MDR Pseudomonas aeruginosa infection J Arca-Suárez, JC Vázquez-Ucha, PA Fraile-Ribot, E Lence, G Cabot, ... Journal of Antimicrobial Chemotherapy 75 (11), 3209-3217, 2020 | 37 | 2020 |
Activity of cefiderocol, imipenem/relebactam, cefepime/taniborbactam and cefepime/zidebactam against ceftolozane/tazobactam-and ceftazidime/avibactam-resistant Pseudomonas … C Lasarte-Monterrubio, PA Fraile-Ribot, JC Vázquez-Ucha, G Cabot, ... Journal of Antimicrobial Chemotherapy 77 (10), 2809-2815, 2022 | 36 | 2022 |
In Vitro and In Vivo Assessment of the Efficacy of Bromoageliferin, an Alkaloid Isolated from the Sponge Agelas dilatata, against Pseudomonas aeruginosa D Pech-Puch, M Pérez-Povedano, M Martinez-Guitian, ... Marine Drugs 18 (6), 326, 2020 | 33 | 2020 |
Antisense inhibition of lpxB gene expression in Acinetobacter baumannii by peptide–PNA conjugates and synergy with colistin M Martínez-Guitián, JC Vázquez-Ucha, L Álvarez-Fraga, K Conde-Pérez, ... Journal of Antimicrobial Chemotherapy 75 (1), 51-59, 2020 | 30 | 2020 |
Kpi, a chaperone-usher pili system associated with the worldwide-disseminated high-risk clone Klebsiella pneumoniae ST-15 E Gato, JC Vázquez-Ucha, S Rumbo-Feal, L Álvarez-Fraga, JA Vallejo, ... Proceedings of the National Academy of Sciences 117 (29), 17249-17259, 2020 | 29 | 2020 |
Challenging antimicrobial susceptibility and evolution of resistance (OXA-681) during treatment of a long-term nosocomial infection caused by a Pseudomonas aeruginosa ST175 clone J Arca-Suárez, P Fraile-Ribot, JC Vázquez-Ucha, G Cabot, ... Antimicrobial agents and chemotherapy 63 (10), 10.1128/aac. 01110-19, 2019 | 27 | 2019 |
Emergence of 16S rRNA methyltransferases among carbapenemase-producing Enterobacterales in Spain studied by whole-genome sequencing J Arca-Suárez, BK Rodiño-Janeiro, A Pérez, P Guijarro-Sánchez, ... International Journal of Antimicrobial Agents 59 (1), 106456, 2022 | 25 | 2022 |
Targeting the motion of shikimate kinase: development of competitive inhibitors that stabilize an inactive open conformation of the enzyme V Prado, E Lence, M Maneiro, JC Vázquez-Ucha, A Beceiro, P Thompson, ... Journal of Medicinal Chemistry 59 (11), 5471-5487, 2016 | 25 | 2016 |
Syzygium aromaticum (clove) and Thymus zygis (thyme) essential oils increase susceptibility to colistin in the nosocomial pathogens Acinetobacter baumannii and Klebsiella … JC Vázquez-Ucha, M Martínez-Guitián, C Lasarte-Monterrubio, ... Biomedicine & Pharmacotherapy 130, 110606, 2020 | 24 | 2020 |
In-Depth Analysis of the Role of the Acinetobactin Cluster in the Virulence of Acinetobacter baumannii K Conde-Pérez, JC Vázquez-Ucha, L Álvarez-Fraga, L Ageitos, ... Frontiers in Microbiology 12, 752070, 2021 | 20 | 2021 |
Global Transcriptomic Analysis During Murine Pneumonia Infection Reveals New Virulence Factors in Acinetobacter baumannii M Martínez-Guitián, JC Vázquez-Ucha, L Álvarez-Fraga, K Conde-Pérez, ... The Journal of Infectious Diseases 223 (8), 1356-1366, 2021 | 18 | 2021 |