| Ancestral sequence reconstruction for protein engineers MA Spence, JA Kaczmarski, JW Saunders, CJ Jackson Current opinion in structural biology 69, 131-141, 2021 | 113 | 2021 |
| Evolution of cyclohexadienyl dehydratase from an ancestral solute-binding protein BE Clifton, JA Kaczmarski, PD Carr, ML Gerth, N Tokuriki, CJ Jackson Nature chemical biology 14 (6), 542-547, 2018 | 107 | 2018 |
| Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity T Izoré, YT Candace Ho, JA Kaczmarski, A Gavriilidou, KH Chow, ... Nature communications 12 (1), 2511, 2021 | 73 | 2021 |
| Kistamicin biosynthesis reveals the biosynthetic requirements for production of highly crosslinked glycopeptide antibiotics A Greule, T Izoré, D Iftime, J Tailhades, M Schoppet, Y Zhao, M Peschke, ... Nature Communications 10 (1), 2613, 2019 | 56 | 2019 |
| T-dependent B cell responses to Plasmodium induce antibodies that form a high-avidity multivalent complex with the circumsporozoite protein CR Fisher, HJ Sutton, JA Kaczmarski, HA McNamara, B Clifton, J Mitchell, ... PLoS pathogens 13 (7), e1006469, 2017 | 52 | 2017 |
| Investigating the size and dynamics of voltage-gated sodium channel fenestrations: A molecular dynamics study JA Kaczmarski, B Corry Channels 8 (3), 264-277, 2014 | 51 | 2014 |
| Ancestral Sequence Reconstruction Identifies Structural Changes Underlying the Evolution of Ideonella sakaiensis PETase and Variants with Improved Stability … Y Joho, V Vongsouthi, MA Spence, J Ton, C Gomez, LL Tan, ... Biochemistry 62 (2), 437-450, 2022 | 48 | 2022 |
| Altered conformational sampling along an evolutionary trajectory changes the catalytic activity of an enzyme JA Kaczmarski, MC Mahawaththa, A Feintuch, BE Clifton, LA Adams, ... Nature communications 11 (1), 5945, 2020 | 44 | 2020 |
| Avid binding by B cells to the Plasmodium circumsporozoite protein repeat suppresses responses to protective subdominant epitopes D Chatterjee, FJ Lewis, HJ Sutton, JA Kaczmarski, X Gao, Y Cai, ... Cell Reports 35 (2), 2021 | 37 | 2021 |
| Structural and evolutionary approaches to the design and optimization of fluorescence-based small molecule biosensors JA Kaczmarski, JA Mitchell, MA Spence, V Vongsouthi, CJ Jackson Current Opinion in Structural Biology 57, 31-38, 2019 | 32 | 2019 |
| Structural Basis for the Allosteric Regulation of the SbtA Bicarbonate Transporter by the PII-like Protein, SbtB, from Cyanobium sp. PCC7001 JA Kaczmarski, NS Hong, B Mukherjee, LT Wey, L Rourke, B Förster, ... Biochemistry 58 (50), 5030-5039, 2019 | 31 | 2019 |
| Drosophila melanogaster nonribosomal peptide synthetase Ebony encodes an atypical condensation domain T Izoré, J Tailhades, MH Hansen, JA Kaczmarski, CJ Jackson, MJ Cryle Proceedings of the National Academy of Sciences 116 (8), 2913-2918, 2019 | 29 | 2019 |
| Potent cyclic peptide inhibitors of FXIIa discovered by mRNA display with genetic code reprogramming DJ Ford, NM Duggan, SE Fry, J Ripoll-Rozada, SM Agten, W Liu, ... Journal of Medicinal Chemistry 64 (11), 7853-7876, 2021 | 21 | 2021 |
| Adenylnucleotide-mediated binding of the PII-like protein SbtB contributes to controlling activity of the cyanobacterial bicarbonate transporter SbtA B Förster, B Mukherjee, LM Rourke, JA Kaczmarski, CJ Jackson, GD Price eLife 12, RP88488, 2023 | 9* | 2023 |
| The role of oligomerization in the optimization of cyclohexadienyl dehydratase conformational dynamics and catalytic activity NJ East, BE Clifton, CJ Jackson, JA Kaczmarski Protein Science 31 (12), e4510, 2022 | 8 | 2022 |
| Exploring performance parameters of artificial allosteric protein switches CE Ayva, MM Fiorito, Z Guo, S Edwardraja, JA Kaczmarski, D Gagoski, ... Journal of Molecular Biology 434 (17), 167678, 2022 | 7 | 2022 |
| Leveraging ancestral sequence reconstruction for protein representation learning DS Matthews, MA Spence, AC Mater, J Nichols, SB Pulsford, M Sandhu, ... Nature Machine Intelligence 6 (12), 1542-1555, 2024 | 4 | 2024 |
| P450-mediated dehydrotyrosine formation during WS9326 biosynthesis proceeds via dehydrogenation of a specific acylated dipeptide substrate S Zhang, L Zhang, A Greule, J Tailhades, E Marschall, P Prasongpholchai, ... Acta Pharmaceutica Sinica B 13 (8), 3561-3574, 2023 | 4 | 2023 |
| Exploring the selectivity and engineering potential of an NRPS condensation domain involved in the biosynthesis of the thermophilic siderophore fuscachelin YTC Ho, T Izoré, JA Kaczmarski, E Marschall, MS Ratnayake, J Tailhades, ... Frontiers in Catalysis 3, 1184959, 2023 | 4 | 2023 |
| Origin Of Evolutionary Bifurcation In An Enzyme CM Miton, EC Campbell, JA Kaczmarski, F Feixas, A Romero-Rivera, ... bioRxiv, 2023.11. 25.568631, 2023 | 2 | 2023 |
Colin JacksonProfessor, Research School of Chemistry, Australian National UniversityVerified email at anu.edu.au
