| Platelets and the immune continuum JW Semple, JE Italiano, J Freedman Nature Reviews Immunology 11 (4), 264-274, 2011 | 1960 | 2011 |
| Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation LH Boudreau, AC Duchez, N Cloutier, D Soulet, N Martin, J Bollinger, ... Blood, The Journal of the American Society of Hematology 124 (14), 2173-2183, 2014 | 685 | 2014 |
| Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-α production in vivo R Aslam, ER Speck, M Kim, AR Crow, KWA Bang, FP Nestel, H Ni, ... Blood 107 (2), 637-641, 2006 | 616 | 2006 |
| Pathogenesis and therapeutic mechanisms in immune thrombocytopenia (ITP) A Zufferey, R Kapur, JW Semple Journal of clinical medicine 6 (2), 16, 2017 | 573 | 2017 |
| Differences in serum cytokine levels in acute and chronic autoimmune thrombocytopenic purpura: relationship to platelet phenotype and antiplatelet T-cell reactivity JW Semple, Y Milev, D Cosgrave, M Mody, A Hornstein, V Blanchette, ... | 507 | 1996 |
| Thrombocytopenia following pfizer and moderna SARS‐CoV‐2 vaccination EJ Lee, DB Cines, T Gernsheimer, C Kessler, M Michel, MD Tarantino, ... American journal of hematology 96 (5), 534-537, 2021 | 479 | 2021 |
| Platelets and innate immunity JW Semple, J Freedman Cellular and Molecular Life Sciences 67, 499-511, 2010 | 426 | 2010 |
| Transfusion-associated circulatory overload and transfusion-related acute lung injury JW Semple, J Rebetz, R Kapur Blood, The Journal of the American Society of Hematology 133 (17), 1840-1853, 2019 | 336 | 2019 |
| Increased antiplatelet T helper lymphocyte reactivity in patients with autoimmune thrombocytopenia JW Semple, J Freedman | 250 | 1991 |
| Cellular immune dysfunction in immune thrombocytopenia (ITP) CGJ McKenzie, L Guo, J Freedman, JW Semple British journal of haematology 163 (1), 10-23, 2013 | 247 | 2013 |
| T granules in human platelets function in TLR9 organization and signaling JN Thon, CG Peters, KR Machlus, R Aslam, J Rowley, H Macleod, ... Journal of Cell Biology 198 (4), 561-574, 2012 | 245 | 2012 |
| Nouvelle cuisine: platelets served with inflammation R Kapur, A Zufferey, E Boilard, JW Semple The Journal of Immunology 194 (12), 5579-5587, 2015 | 232 | 2015 |
| A murine model of severe immune thrombocytopenia is induced by antibody- and CD8+ T cell–mediated responses that are differentially sensitive to therapy L Chow, R Aslam, ER Speck, M Kim, N Cridland, ML Webster, P Chen, ... Blood, The Journal of the American Society of Hematology 115 (6), 1247-1253, 2010 | 230 | 2010 |
| HLA alloimmunization against platelet transfusions: pathophysiology, significance, prevention and management K Pavenski, J Freedman, JW Semple Tissue antigens 79 (4), 237-245, 2012 | 215 | 2012 |
| The immune nature of platelets revisited A Maouia, J Rebetz, R Kapur, JW Semple Transfusion medicine reviews 34 (4), 209-220, 2020 | 199 | 2020 |
| Platelet-bound lipopolysaccharide enhances Fc receptor–mediated phagocytosis of IgG-opsonized platelets JW Semple, R Aslam, M Kim, ER Speck, J Freedman Blood, The Journal of the American Society of Hematology 109 (11), 4803-4805, 2007 | 190 | 2007 |
| Pathogenesis of immune thrombocytopenia DB Cines, A Cuker, JW Semple La Presse Médicale 43 (4), e49-e59, 2014 | 177 | 2014 |
| Cellular immune mechanisms in autoimmune thrombocytopenic purpura: An update MD Coopamah, MB Garvey, J Freedman, JW Semple Transfusion medicine reviews 17 (1), 69-80, 2003 | 165 | 2003 |
| IVIg inhibits reticuloendothelial system function and ameliorates murine passive‐immune thrombocytopenia independent of anti‐idiotype reactivity AR Crow, S Song, JW Semple, J Freedman, AH Lazarus British journal of haematology 115 (3), 679-686, 2001 | 152 | 2001 |
| Immune pathophysiology of autoimmune thrombocytopenic purpura JW Semple Blood reviews 16 (1), 9-12, 2002 | 146 | 2002 |
j freedmanSt Michaels HospitalVerified email at smh.ca