Applications of machine learning in drug discovery and development J Vamathevan, D Clark, P Czodrowski, I Dunham, E Ferran, G Lee, B Li, ... Nature reviews Drug discovery 18 (6), 463-477, 2019 | 2510 | 2019 |
DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae JF Heidelberg, JA Eisen, WC Nelson, RA Clayton, ML Gwinn, RJ Dodson, ... Nature 406 (6795), 477-483, 2000 | 2233 | 2000 |
Insights on Evolution of Virulence and Resistance from the Complete Genome Analysis of an Early Methicillin-Resistant Staphylococcus aureus Strain and a Biofilm-Producing … SR Gill, DE Fouts, GL Archer, EF Mongodin, RT DeBoy, J Ravel, ... Journal of bacteriology 187 (7), 2426-2438, 2005 | 1468 | 2005 |
Complete genome sequence of Neisseria meningitidis serogroup B strain MC58 H Tettelin, NJ Saunders, J Heidelberg, AC Jeffries, KE Nelson, JA Eisen, ... Science 287 (5459), 1809-1815, 2000 | 1426 | 2000 |
Genome Sequence of the Radioresistant Bacterium Deinococcus radiodurans R1 O White, JA Eisen, JF Heidelberg, EK Hickey, JD Peterson, RJ Dodson, ... Science 286 (5444), 1571-1577, 1999 | 1222 | 1999 |
Role of Mobile DNA in the Evolution of Vancomycin-Resistant Enterococcus faecalis IT Paulsen, L Banerjei, GSA Myers, KE Nelson, R Seshadri, TD Read, ... Science 299 (5615), 2071-2074, 2003 | 1132 | 2003 |
Genome sequence of the dissimilatory metal ion–reducing bacterium Shewanella oneidensis JF Heidelberg, IT Paulsen, KE Nelson, EJ Gaidos, WC Nelson, TD Read, ... Nature biotechnology 20 (11), 1118-1123, 2002 | 1062 | 2002 |
Phylogenomics of the Reproductive Parasite Wolbachia pipientis wMel: A Streamlined Genome Overrun by Mobile Genetic Elements M Wu, LV Sun, J Vamathevan, M Riegler, R Deboy, JC Brownlie, ... PLoS biology 2 (3), e69, 2004 | 1005 | 2004 |
The Genome of the Basidiomycetous Yeast and Human Pathogen Cryptococcus neoformans BJ Loftus, E Fung, P Roncaglia, D Rowley, P Amedeo, D Bruno, ... Science 307 (5713), 1321-1324, 2005 | 886 | 2005 |
Complete genome sequence of Caulobacter crescentus WC Nierman, TV Feldblyum, MT Laub, IT Paulsen, KE Nelson, J Eisen, ... Proceedings of the National Academy of Sciences 98 (7), 4136-4141, 2001 | 653 | 2001 |
Open Targets: a platform for therapeutic target identification and validation G Koscielny, P An, D Carvalho-Silva, JA Cham, L Fumis, R Gasparyan, ... Nucleic acids research 45 (D1), D985-D994, 2017 | 498 | 2017 |
The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium JA Eisen, KE Nelson, IT Paulsen, JF Heidelberg, M Wu, RJ Dodson, ... Proceedings of the National Academy of Sciences 99 (14), 9509-9514, 2002 | 406 | 2002 |
Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1 EF Mongodin, N Shapir, SC Daugherty, RT DeBoy, JB Emerson, ... PLoS genetics 2 (12), e214, 2006 | 284 | 2006 |
GA4GH: International policies and standards for data sharing across genomic research and healthcare HL Rehm, AJH Page, L Smith, JB Adams, G Alterovitz, LJ Babb, ... Cell genomics 1 (2), 2021 | 191 | 2021 |
Comparative genomics of Klebsiella pneumoniae strains with different antibiotic resistance profiles V Kumar, P Sun, J Vamathevan, Y Li, K Ingraham, L Palmer, J Huang, ... Antimicrobial agents and chemotherapy 55 (9), 4267-4276, 2011 | 153 | 2011 |
The role of positive selection in determining the molecular cause of species differences in disease JJ Vamathevan, S Hasan, RD Emes, H Amrine-Madsen, D Rajagopalan, ... BMC Evolutionary Biology 8, 1-14, 2008 | 92 | 2008 |
Genomics in healthcare: GA4GH looks to 2022 E Birney, J Vamathevan, P Goodhand BioRxiv, 203554, 2017 | 82 | 2017 |
The application of next-generation sequencing technologies to drug discovery and development PM Woollard, NAL Mehta, JJ Vamathevan, S Van Horn, BK Bonde, ... Drug discovery today 16 (11-12), 512-519, 2011 | 79 | 2011 |
Minipig and beagle animal model genomes aid species selection in pharmaceutical discovery and development JJ Vamathevan, MD Hall, S Hasan, PM Woollard, M Xu, Y Yang, X Li, ... Toxicology and applied pharmacology 270 (2), 149-157, 2013 | 71 | 2013 |
Sequencing Bacillus anthracis Typing Phages Gamma and Cherry Reveals a Common Ancestry DE Fouts, DA Rasko, RZ Cer, L Jiang, NB Fedorova, A Shvartsbeyn, ... Journal of bacteriology 188 (9), 3402-3408, 2006 | 59 | 2006 |