PI3K/AKT signaling pathway and cancer: an updated review M Martini, MC De Santis, L Braccini, F Gulluni, E Hirsch Annals of medicine 46 (6), 372-383, 2014 | 1258 | 2014 |
Spatiotemporal control of endocytosis by phosphatidylinositol-3, 4-bisphosphate Y Posor, M Eichhorn-Gruenig, D Puchkov, J Schöneberg, A Ullrich, ... Nature 499 (7457), 233-237, 2013 | 469 | 2013 |
PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium function I Franco, F Gulluni, CC Campa, C Costa, JP Margaria, E Ciraolo, ... Developmental cell 28 (6), 647-658, 2014 | 218 | 2014 |
Class II PI3K functions in cell biology and disease F Gulluni, MC De Santis, JP Margaria, M Martini, E Hirsch Trends in cell biology 29 (4), 339-359, 2019 | 137 | 2019 |
Targeting PI3K in cancer: any good news? M Martini, E Ciraolo, F Gulluni, E Hirsch Frontiers in oncology 3, 108, 2013 | 133 | 2013 |
Targeting PI3K/AKT/mTOR signaling pathway in breast cancer H Li, L Prever, E Hirsch, F Gulluni Cancers 13 (14), 3517, 2021 | 123 | 2021 |
In Vivo Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K–AKT Signaling at Endosomes C Li Chew, A Lunardi, F Gulluni, DT Ruan, M Chen, L Salmena, ... Cancer discovery 5 (7), 740-751, 2015 | 113 | 2015 |
Targeting PI3K signaling in cancer: Challenges and advances MC De Santis, F Gulluni, CC Campa, M Martini, E Hirsch Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1871 (2), 361-366, 2019 | 94 | 2019 |
Mitotic spindle assembly and genomic stability in breast cancer require PI3K-C2α scaffolding function F Gulluni, M Martini, MC De Santis, CC Campa, A Ghigo, JP Margaria, ... Cancer Cell 32 (4), 444-459. e7, 2017 | 90 | 2017 |
PI (3, 4) P2 signaling in cancer and metabolism L Gozzelino, MC De Santis, F Gulluni, E Hirsch, M Martini Frontiers in oncology 10, 360, 2020 | 70 | 2020 |
Mutations in PIK3C2A cause syndromic short stature, skeletal abnormalities, and cataracts associated with ciliary dysfunction D Tiosano, HN Baris, A Chen, MM Hitzert, M Schueler, F Gulluni, ... PLoS genetics 15 (4), e1008088, 2019 | 57 | 2019 |
Phosphoinositide 3-kinase-C2α regulates polycystin-2 ciliary entry and protects against kidney cyst formation I Franco, JP Margaria, MC De Santis, A Ranghino, D Monteyne, ... Journal of the American Society of Nephrology 27 (4), 1135-1144, 2016 | 56 | 2016 |
Autoregulation of class II alpha PI3K activity by its lipid-binding PX-C2 domain module H Wang, WT Lo, AV Žagar, F Gulluni, M Lehmann, L Scapozza, V Haucke, ... Molecular cell 71 (2), 343-351. e4, 2018 | 49 | 2018 |
PI (3, 4) P2-mediated cytokinetic abscission prevents early senescence and cataract formation F Gulluni, L Prever, H Li, P Krafcikova, I Corrado, WT Lo, JP Margaria, ... Science 374 (6573), eabk0410, 2021 | 40 | 2021 |
Structural basis of phosphatidylinositol 3-kinase C2α function WT Lo, Y Zhang, O Vadas, Y Roske, F Gulluni, MC De Santis, AV Zagar, ... Nature Structural & Molecular Biology 29 (3), 218-228, 2022 | 25 | 2022 |
Methods to measure the enzymatic activity of PI3Ks E Ciraolo, F Gulluni, E Hirsch Methods in enzymology 543, 115-140, 2014 | 22 | 2014 |
Lysosomal lipid switch sensitises to nutrient deprivation and mTOR targeting in pancreatic cancer MC De Santis, L Gozzelino, JP Margaria, A Costamagna, E Ratto, ... Gut 72 (2), 360-371, 2023 | 18 | 2023 |
Phosphoinositides in cell proliferation and metabolism E Hirsch, F Gulluni, M Martini Advances in Biological Regulation 75, 100693, 2020 | 18 | 2020 |
Downregulation of class II phosphoinositide 3-kinase PI3K-C2β delays cell division and potentiates the effect of docetaxel on cancer cell growth O Cisse, M Quraishi, F Gulluni, F Guffanti, I Mavrommati, ... Journal of Experimental & Clinical Cancer Research 38, 1-19, 2019 | 18 | 2019 |
Cytokinetic Abscission: Phosphoinositides and ESCRT S Direct the Final Cut F Gulluni, M Martini, E Hirsch Journal of Cellular Biochemistry 118 (11), 3561-3568, 2017 | 17 | 2017 |