| Allele-selective lowering of mutant HTT protein by HTT–LC3 linker compounds Z Li, C Wang, Z Wang, C Zhu, J Li, T Sha, L Ma, C Gao, YI Yang, Y Sun, ... Nature 575 (7781), 203-209, 2019 | 417 | 2019 |
| Molecular glues for targeted protein degradation: from serendipity to rational discovery G Dong, Y Ding, S He, C Sheng Journal of medicinal chemistry 64 (15), 10606-10620, 2021 | 238 | 2021 |
| Emerging new concepts of degrader technologies Y Ding, Y Fei, B Lu Trends in Pharmacological Sciences 41 (7), 464-474, 2020 | 154 | 2020 |
| ATTEC: a potential new approach to target proteinopathies Z Li, C Zhu, Y Ding, Y Fei, B Lu Autophagy 16 (1), 185-187, 2020 | 144 | 2020 |
| Degradation of lipid droplets by chimeric autophagy-tethering compounds Y Fu, N Chen, Z Wang, S Luo, Y Ding, B Lu Cell research 31 (9), 965-979, 2021 | 133 | 2021 |
| A novel method for high‐level production of TEV protease by superfolder GFP Tag X Wu, D Wu, Z Lu, W Chen, X Hu, Y Ding BioMed Research International 2009 (1), 591923, 2009 | 90 | 2009 |
| Glyco-regioisomerism effect on lectin-binding and cell-uptake pathway of glycopolymer-containing nanoparticles P Sun, Y He, M Lin, Y Zhao, Y Ding, G Chen, M Jiang ACS macro letters 3 (1), 96-101, 2014 | 69 | 2014 |
| Emerging degrader technologies engaging lysosomal pathways Y Ding, D Xing, Y Fei, B Lu Chemical Society Reviews 51 (21), 8832-8876, 2022 | 64 | 2022 |
| (−)-Epigallocatechin-3-gallate (EGCG) inhibits fibrillation, disaggregates amyloid fibrils of α-synuclein, and protects PC12 cells against α-synuclein-induced toxicity J Zhao, Q Liang, Q Sun, C Chen, L Xu, Y Ding, P Zhou Rsc Advances 7 (52), 32508-32517, 2017 | 64 | 2017 |
| Natural products triptolide, celastrol, and withaferin A inhibit the chaperone activity of peroxiredoxin I Q Zhao, Y Ding, Z Deng, OY Lee, P Gao, P Chen, RJ Rose, H Zhao, ... Chemical science 6 (7), 4124-4130, 2015 | 56 | 2015 |
| Metal chelator EGCG attenuates Fe (III)‐induced conformational transition of α‐synuclein and protects AS‐PC 12 cells against Fe (III)‐induced death J Zhao, L Xu, Q Liang, Q Sun, C Chen, Y Zhang, Y Ding, P Zhou Journal of Neurochemistry 143 (1), 136-146, 2017 | 52 | 2017 |
| Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models M Yu, Y Fu, Y Liang, H Song, Y Yao, P Wu, Y Yao, Y Pan, X Wen, L Ma, ... Cell Research 27 (12), 1441-1465, 2017 | 50 | 2017 |
| Structure-based engineering of anti-GFP nanobody tandems as ultra-high-affinity reagents for purification Z Zhang, Y Wang, Y Ding, M Hattori Scientific reports 10 (1), 6239, 2020 | 49 | 2020 |
| cAMP/protein kinase A signalling pathway protects against neuronal apoptosis and is associated with modulation of Kv2.1 in cerebellar granule cells S Jiao, Z Liu, WH Ren, Y Ding, YQ Zhang, ZH Zhang, YA Mei Journal of neurochemistry 100 (4), 979-991, 2007 | 45 | 2007 |
| Ispinesib as an effective warhead for the design of autophagosome-tethering chimeras: discovery of potent degraders of nicotinamide phosphoribosyltransferase (NAMPT) G Dong, Y Wu, J Cheng, L Chen, R Liu, Y Ding, S Wu, J Ma, C Sheng Journal of medicinal chemistry 65 (11), 7619-7628, 2022 | 44 | 2022 |
| A highly stable human single-domain antibody-drug conjugate exhibits superior penetration and treatment of solid tumors Y Wu, Q Li, Y Kong, Z Wang, C Lei, J Li, L Ding, C Wang, Y Cheng, Y Wei, ... Molecular Therapy 30 (8), 2785-2799, 2022 | 40 | 2022 |
| TR-FRET assays of Huntingtin protein fragments reveal temperature and polyQ length-dependent conformational changes X Cui, Q Liang, Y Liang, M Lu, Y Ding, B Lu Scientific reports 4 (1), 5601, 2014 | 40 | 2014 |
| Complex of EGCG with Cu (II) suppresses amyloid aggregation and Cu (II)-induced cytotoxicity of α-synuclein Y Teng, J Zhao, L Ding, Y Ding, P Zhou Molecules 24 (16), 2940, 2019 | 39 | 2019 |
| Structural insights into the mechanism of single domain VHH antibody binding to cortisol L Ding, Z Wang, P Zhong, H Jiang, Z Zhao, Y Zhang, Z Ren, Y Ding FEBS letters 593 (11), 1248-1256, 2019 | 38 | 2019 |
| Using green and red fluorescent proteins to teach protein expression, purification, and crystallization Y Wu, Y Zhou, J Song, X Hu, Y Ding, Z Zhang Biochemistry and Molecular Biology Education 36 (1), 43-54, 2008 | 36 | 2008 |
Boxun LuFudan UniversityVerified email at fudan.edu.cn