Glutamate translocation of the neuronal glutamate transporter EAAC1 occurs within milliseconds C Grewer, N Watzke, M Wiessner, T Rauen Proceedings of the National Academy of Sciences 97 (17), 9706-9711, 2000 | 219 | 2000 |
Glutamate forward and reverse transport: from molecular mechanism to transporter‐mediated release after ischemia C Grewer, A Gameiro, Z Zhang, Z Tao, S Braams, T Rauen IUBMB life 60 (9), 609-619, 2008 | 214 | 2008 |
Electrogenic glutamate transporters in the CNS: molecular mechanism, pre-steady-state kinetics, and their impact on synaptic signaling C Grewer, T Rauen The Journal of membrane biology 203, 1-20, 2005 | 199 | 2005 |
Mechanism of the triplet-state quenching by molecular oxygen in solution C Grewer, HD Brauer The Journal of Physical Chemistry 98 (16), 4230-4235, 1994 | 187 | 1994 |
Individual subunits of the glutamate transporter EAAC1 homotrimer function independently of each other C Grewer, P Balani, C Weidenfeller, T Bartusel, Z Tao, T Rauen Biochemistry 44 (35), 11913-11923, 2005 | 165 | 2005 |
Early intermediates in the transport cycle of the neuronal excitatory amino acid carrier EAAC1 N Watzke, E Bamberg, C Grewer The Journal of general physiology 117 (6), 547-562, 2001 | 141 | 2001 |
SLC1 glutamate transporters C Grewer, A Gameiro, T Rauen Pflügers Archiv-European Journal of Physiology 466, 3-24, 2014 | 137 | 2014 |
New inhibitors for the neutral amino acid transporter ASCT2 reveal its Na+‐dependent anion leak C Grewer, E Grabsch The Journal of physiology 557 (3), 747-759, 2004 | 133 | 2004 |
Cloning, transport properties, and differential localization of two splice variants of GLT‐1 in the rat CNS: Implications for CNS glutamate homeostasis R Sullivan, T Rauen, F Fischer, M Wießner, C Grewer, A Bicho, DV Pow Glia 45 (2), 155-169, 2004 | 121 | 2004 |
The glutamate transporter subtypes EAAT4 and EAATs 1-3 transport glutamate with dramatically different kinetics and voltage dependence but share a common uptake mechanism C Mim, P Balani, T Rauen, C Grewer Journal of General Physiology 126 (6), 571-589, 2005 | 106 | 2005 |
Neutralization of the aspartic acid residue Asp-367, but not Asp-454, inhibits binding of Na+ to the glutamate-free form and cycling of the glutamate transporter EAAC1 Z Tao, Z Zhang, C Grewer Journal of Biological Chemistry 281 (15), 10263-10272, 2006 | 88 | 2006 |
Ligand discovery for the alanine-serine-cysteine transporter (ASCT2, SLC1A5) from homology modeling and virtual screening C Colas, C Grewer, A Gameiro, T Albers, K Singh, NJ Otte, H Shere, ... Biophysical Journal 108 (2), 54a, 2015 | 81 | 2015 |
Currents in response to rapid concentration jumps of amphetamine uncover novel aspects of human dopamine transporter function K Erreger, C Grewer, JA Javitch, A Galli Journal of Neuroscience 28 (4), 976-989, 2008 | 79 | 2008 |
[25] Development and application of caged ligands for neurotransmitter receptors in transient kinetic and neuronal circuit mapping studies GP Hess, C Grewer Methods in enzymology 291, 443-473, 1998 | 79 | 1998 |
Transport direction determines the kinetics of substrate transport by the glutamate transporter EAAC1 Z Zhang, Z Tao, A Gameiro, S Barcelona, S Braams, T Rauen, C Grewer Proceedings of the National Academy of Sciences 104 (46), 18025-18030, 2007 | 75 | 2007 |
A new photolabile precursor of glycine with improved properties: A tool for chemical kinetic investigations of the glycine receptor C Grewer, J Jäger, BK Carpenter, GP Hess Biochemistry 39 (8), 2063-2070, 2000 | 75 | 2000 |
The discovery of slowness: low-capacity transport and slow anion channel gating by the glutamate transporter EAAT5 A Gameiro, S Braams, T Rauen, C Grewer Biophysical journal 100 (11), 2623-2632, 2011 | 74 | 2011 |
Is the glutamate residue Glu-373 the proton acceptor of the excitatory amino acid carrier 1? C Grewer, N Watzke, T Rauen, A Bicho Journal of Biological Chemistry 278 (4), 2585-2592, 2003 | 72 | 2003 |
A rational approach to the design of selective substrates and potent nontransportable inhibitors of the excitatory amino acid transporter EAAC1 (EAAT3). New glutamate and … G Campiani, M De Angelis, S Armaroli, C Fattorusso, B Catalanotti, ... Journal of medicinal chemistry 44 (16), 2507-2510, 2001 | 68 | 2001 |
Mechanism-based discovery of ligands that counteract inhibition of the nicotinic acetylcholine receptor by cocaine and MK-801 GP Hess, H Ulrich, HG Breitinger, L Niu, AM Gameiro, C Grewer, ... Proceedings of the National Academy of Sciences 97 (25), 13895-13900, 2000 | 68 | 2000 |