Inhibiting the hedgehog pathway in patients with the basal-cell nevus syndrome JY Tang, JM Mackay-Wiggan, M Aszterbaum, RL Yauch, J Lindgren, ... New England Journal of Medicine 366 (23), 2180-2188, 2012 | 656 | 2012 |
Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth J Kim, JY Tang, R Gong, J Kim, JJ Lee, KV Clemons, CR Chong, ... Cancer cell 17 (4), 388-399, 2010 | 606 | 2010 |
Smoothened variants explain the majority of drug resistance in basal cell carcinoma SX Atwood, KY Sarin, RJ Whitson, JR Li, G Kim, M Rezaee, MS Ally, J Kim, ... Cancer cell 27 (3), 342-353, 2015 | 451 | 2015 |
Genomic analysis of smoothened inhibitor resistance in basal cell carcinoma HJ Sharpe, G Pau, GJ Dijkgraaf, N Basset-Seguin, Z Modrusan, ... Cancer cell 27 (3), 327-341, 2015 | 422 | 2015 |
Itraconazole and arsenic trioxide inhibit Hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonists J Kim, BT Aftab, JY Tang, D Kim, AH Lee, M Rezaee, J Kim, B Chen, ... Cancer cell 23 (1), 23-34, 2013 | 411 | 2013 |
Xeroderma pigmentosum p48 gene enhances global genomic repair and suppresses UV-induced mutagenesis JY Tang, BJ Hwang, JM Ford, PC Hanawalt, G Chu Molecular cell 5 (4), 737-744, 2000 | 389 | 2000 |
Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition Y Tang, S Gholamin, S Schubert, MI Willardson, A Lee, P Bandopadhayay, ... Nature medicine 20 (7), 732-740, 2014 | 337 | 2014 |
Open-label, exploratory phase II trial of oral itraconazole for the treatment of basal cell carcinoma DJ Kim, J Kim, K Spaunhurst, J Montoya, R Khodosh, K Chandra, T Fu, ... Journal of Clinical Oncology 32 (8), 745-751, 2014 | 337 | 2014 |
GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas SX Atwood, M Li, A Lee, JY Tang, AE Oro Nature 494 (7438), 484-488, 2013 | 282 | 2013 |
Xeroderma pigmentosum complementation group E and UV-damaged DNA-binding protein J Tang, G Chu DNA repair 1 (8), 601-616, 2002 | 248 | 2002 |
Safety and wound outcomes following genetically corrected autologous epidermal grafts in patients with recessive dystrophic epidermolysis bullosa Z Siprashvili, NT Nguyen, ES Gorell, K Loutit, P Khuu, LK Furukawa, ... Jama 316 (17), 1808-1817, 2016 | 225 | 2016 |
An investigator-initiated open-label clinical trial of vismodegib as a neoadjuvant to surgery for high-risk basal cell carcinoma MS Ally, S Aasi, A Wysong, C Teng, E Anderson, I Bailey-Healy, A Oro, ... Journal of the American Academy of Dermatology 71 (5), 904-911. e1, 2014 | 163 | 2014 |
Toxicity from radiation therapy associated with abnormal transcriptional responses to DNA damage KE Rieger, WJ Hong, VG Tusher, J Tang, R Tibshirani, G Chu Proceedings of the National Academy of Sciences 101 (17), 6635-6640, 2004 | 161 | 2004 |
Sun protective behaviors and vitamin D levels in the US population: NHANES 2003–2006 E Linos, E Keiser, M Kanzler, KL Sainani, W Lee, E Vittinghoff, MM Chren, ... Cancer Causes & Control 23, 133-140, 2012 | 159 | 2012 |
Genome-wide association study identifies novel susceptibility loci for cutaneous squamous cell carcinoma HS Chahal, Y Lin, KJ Ransohoff, DA Hinds, W Wu, HJ Dai, AA Qureshi, ... Nature communications 7 (1), 12048, 2016 | 156 | 2016 |
Inhibition of the hedgehog pathway in patients with basal-cell nevus syndrome: final results from the multicentre, randomised, double-blind, placebo-controlled, phase 2 trial JY Tang, MS Ally, AM Chanana, JM Mackay-Wiggan, M Aszterbaum, ... The lancet oncology 17 (12), 1720-1731, 2016 | 152 | 2016 |
Calcium plus vitamin D supplementation and the risk of nonmelanoma and melanoma skin cancer: post hoc analyses of the women's health initiative randomized controlled trial JY Tang, T Fu, E LeBlanc, JAE Manson, D Feldman, E Linos, MZ Vitolins, ... Journal of clinical oncology 29 (22), 3078-3084, 2011 | 151 | 2011 |
Vitamin D3 inhibits hedgehog signaling and proliferation in murine Basal cell carcinomas JY Tang, TZ Xiao, Y Oda, KS Chang, E Shpall, A Wu, PL So, J Hebert, ... Cancer prevention research 4 (5), 744-751, 2011 | 147 | 2011 |
Update on metastatic basal cell carcinoma: a summary of published cases from 1981 through 2011 A Wysong, SZ Aasi, JY Tang JAMA dermatology 149 (5), 615-616, 2013 | 142 | 2013 |
Hat, shade, long sleeves, or sunscreen? Rethinking US sun protection messages based on their relative effectiveness E Linos, E Keiser, T Fu, G Colditz, S Chen, JY Tang Cancer Causes & Control 22, 1067-1071, 2011 | 127 | 2011 |