Proteome integral solubility alteration: a high-throughput proteomics assay for target deconvolution M Gaetani, P Sabatier, AA Saei, CM Beusch, Z Yang, SL Lundström, ... Journal of proteome research 18 (11), 4027-4037, 2019 | 227 | 2019 |
Comprehensive chemical proteomics for target deconvolution of the redox active drug auranofin AA Saei, H Gullberg, P Sabatier, CM Beusch, K Johansson, B Lundgren, ... Redox biology 32, 101491, 2020 | 87 | 2020 |
ProTargetMiner as a proteome signature library of anticancer molecules for functional discovery AA Saei, CM Beusch, A Chernobrovkin, P Sabatier, B Zhang, ÜG Tokat, ... Nature communications 10 (1), 5715, 2019 | 74 | 2019 |
System-wide identification and prioritization of enzyme substrates by thermal analysis AA Saei, CM Beusch, P Sabatier, JA Wells, H Gharibi, Z Meng, ... Nature communications 12 (1), 1296, 2021 | 65* | 2021 |
Comprehensive chemical proteomics analyses reveal that the new TRi-1 and TRi-2 compounds are more specific thioredoxin reductase 1 inhibitors than auranofin P Sabatier, CM Beusch, R Gencheva, Q Cheng, R Zubarev, ESJ Arnér Redox Biology 48, 102184, 2021 | 39 | 2021 |
One-Tip enables comprehensive proteome coverage in minimal cells and single zygotes Z Ye, P Sabatier, J Martin-Gonzalez, A Eguchi, M Lechner, O Østergaard, ... nature communications 15 (1), 2474, 2024 | 34 | 2024 |
An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation P Sabatier, CM Beusch, AA Saei, M Aoun, N Moruzzi, A Coelho, N Leijten, ... Nature communications 12 (1), 6558, 2021 | 33 | 2021 |
Comparative proteomics of dying and surviving cancer cells improves the identification of drug targets and sheds light on cell life/death decisions AA Saei, P Sabatier, ÜG Tokat, A Chernobrovkin, M Pirmoradian, ... Molecular & Cellular Proteomics 17 (6), 1144-1155, 2018 | 31 | 2018 |
Ion-based proteome-integrated solubility alteration assays for systemwide profiling of protein–molecule interactions CM Beusch, P Sabatier, RA Zubarev Analytical Chemistry 94 (19), 7066-7074, 2022 | 27 | 2022 |
GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics SC Wright, A Motso, S Koutsilieri, CM Beusch, P Sabatier, A Berghella, ... Nature communications 14 (1), 6243, 2023 | 26 | 2023 |
Vitamin D3 receptor polymorphisms regulate T cells and T cell-dependent inflammatory diseases G Fernandez Lahore, B Raposo, M Lagerquist, C Ohlsson, P Sabatier, ... Proceedings of the National Academy of Sciences 117 (40), 24986-24997, 2020 | 26 | 2020 |
Enhanced sensitivity and scalability with a Chip-Tip workflow enables deep single-cell proteomics Z Ye, P Sabatier, L van der Hoeven, MY Lechner, T Phlairaharn, ... Nature Methods, 1-11, 2025 | 20* | 2025 |
Dynamic proteomics reveals high plasticity of cellular proteome: growth‐related and drug‐induced changes in cancer cells are comparable P Sabatier, AA Saei, S Wang, RA Zubarev Proteomics 18 (24), 1800118, 2018 | 16 | 2018 |
Polymorphic estrogen receptor binding site causes Cd2-dependent sex bias in the susceptibility to autoimmune diseases G Fernandez Lahore, M Förster, M Johannesson, P Sabatier, E Lönnblom, ... Nature Communications 12 (1), 5565, 2021 | 15 | 2021 |
Wnt/β-catenin and NFκB signaling synergize to trigger growth factor-free regeneration of adult primary human hepatocytes N Oliva-Vilarnau, CM Beusch, P Sabatier, E Sakaraki, A Tjaden, L Graetz, ... Hepatology 79 (6), 1337-1351, 2024 | 14 | 2024 |
System-wide profiling by proteome integral solubility alteration assay of drug residence times for target characterization P Sabatier, CM Beusch, Z Meng, RA Zubarev Analytical Chemistry 94 (45), 15772-15780, 2022 | 10 | 2022 |
Comprehensive target screening and cellular profiling of the cancer-active compound b-AP15 indicate abrogation of protein homeostasis and organelle dysfunction as the primary … J Gubat, K Selvaraju, L Sjöstrand, D Kumar Singh, MV Turkina, ... Frontiers in Oncology 12, 852980, 2022 | 9 | 2022 |
Antigen-presenting autoreactive B cells activate regulatory T cells and suppress autoimmune arthritis in mice M Aoun, A Coelho, A Krämer, A Saxena, P Sabatier, CM Beusch, ... Journal of Experimental Medicine 220 (11), e20230101, 2023 | 8 | 2023 |
Therapy targeting antigen-specific T cells by a peptide-based tolerizing vaccine against autoimmune arthritis V Urbonaviciute, L Romero-Castillo, B Xu, H Luo, N Schneider, S Weisse, ... Proceedings of the National Academy of Sciences 120 (25), e2218668120, 2023 | 8 | 2023 |
A “spindle and thread” mechanism unblocks p53 translation by modulating N-terminal disorder M Kaldmäe, T Vosselman, X Zhong, D Lama, G Chen, M Saluri, ... Structure 30 (5), 733-742. e7, 2022 | 7 | 2022 |