Controlling the SARS-CoV-2 spike glycoprotein conformation R Henderson, RJ Edwards, K Mansouri, K Janowska, V Stalls, ... Nature structural & molecular biology 27 (10), 925-933, 2020 | 437 | 2020 |
Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity SMC Gobeil, K Janowska, S McDowell, K Mansouri, R Parks, V Stalls, ... Science 373 (6555), eabi6226, 2021 | 401 | 2021 |
D614G mutation alters SARS-CoV-2 spike conformation and enhances protease cleavage at the S1/S2 junction SMC Gobeil, K Janowska, S McDowell, K Mansouri, R Parks, K Manne, ... Cell reports 34 (2), 2021 | 295 | 2021 |
Structural diversity of the SARS-CoV-2 Omicron spike SMC Gobeil, R Henderson, V Stalls, K Janowska, X Huang, A May, ... Molecular cell 82 (11), 2050-2068. e6, 2022 | 177 | 2022 |
Targeted selection of HIV-specific antibody mutations by engineering B cell maturation KO Saunders, K Wiehe, M Tian, P Acharya, T Bradley, SM Alam, EP Go, ... Science 366 (6470), eaay7199, 2019 | 150 | 2019 |
Cryo-EM structures of SARS-CoV-2 Omicron BA. 2 spike V Stalls, J Lindenberger, SMC Gobeil, R Henderson, R Parks, M Barr, ... Cell Reports 39 (13), 2022 | 94 | 2022 |
Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies WB Williams, RR Meyerhoff, RJ Edwards, H Li, K Manne, NI Nicely, ... Cell 184 (11), 2955-2972. e25, 2021 | 85 | 2021 |
Cold sensitivity of the SARS-CoV-2 spike ectodomain RJ Edwards, K Mansouri, V Stalls, K Manne, B Watts, R Parks, ... Nature Structural & Molecular Biology 28 (2), 128-131, 2021 | 76 | 2021 |
Inference of the HIV-1 VRC01 antibody lineage unmutated common ancestor reveals alternative pathways to overcome a key glycan barrier M Bonsignori, E Scott, K Wiehe, D Easterhoff, SM Alam, KK Hwang, ... Immunity 49 (6), 1162-1174. e8, 2018 | 67 | 2018 |
Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies CC LaBranche, R Henderson, A Hsu, S Behrens, X Chen, T Zhou, ... PLoS pathogens 15 (9), e1008026, 2019 | 66 | 2019 |
Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements R Henderson, M Lu, Y Zhou, Z Mu, R Parks, Q Han, AL Hsu, E Carter, ... Nature communications 11 (1), 520, 2020 | 54 | 2020 |
mRNA-encoded HIV-1 Env trimer ferritin nanoparticles induce monoclonal antibodies that neutralize heterologous HIV-1 isolates in mice Z Mu, K Wiehe, KO Saunders, R Henderson, DW Cain, R Parks, D Martik, ... Cell Reports 38 (11), 2022 | 50 | 2022 |
Glycans on the SARS-CoV-2 spike control the receptor binding domain conformation R Henderson, RJ Edwards, K Mansouri, K Janowska, V Stalls, M Kopp, ... BioRxiv, 2020 | 49 | 2020 |
Selection of immunoglobulin elbow region mutations impacts interdomain conformational flexibility in HIV-1 broadly neutralizing antibodies R Henderson, BE Watts, HN Ergin, K Anasti, R Parks, SM Xia, A Trama, ... Nature communications 10 (1), 654, 2019 | 37 | 2019 |
A glycan cluster on the SARS-CoV-2 spike ectodomain is recognized by Fab-dimerized glycan-reactive antibodies P Acharya, W Williams, R Henderson, K Janowska, K Manne, R Parks, ... BioRxiv, 2020.06. 30.178897, 2020 | 27 | 2020 |
Regulation of structural dynamics within a signal recognition particle promotes binding of protein targeting substrates F Gao, AD Kight, R Henderson, S Jayanthi, P Patel, M Murchison, ... Journal of Biological Chemistry 290 (25), 15462-15474, 2015 | 25 | 2015 |
D614G mutation alters SARS-CoV-2 spike conformational dynamics and protease cleavage susceptibility at the S1/S2 junction SMC Gobeil, K Janowska, S McDowell, K Mansouri, R Parks, K Manne, ... BioRxiv, 2020.10. 11.335299, 2020 | 22 | 2020 |
Vaccine induction of CD4-mimicking HIV-1 broadly neutralizing antibody precursors in macaques KO Saunders, J Counts, B Thakur, V Stalls, R Edwards, K Manne, X Lu, ... Cell 187 (1), 79-94. e24, 2024 | 20 | 2024 |
Targeted selection of HIV-specific antibody mutations by engineering B cell maturation. Science 366: eaay7199 KO Saunders, K Wiehe, M Tian, P Acharya, T Bradley, SM Alam, EP Go, ... | 14 | 2019 |
Domain organization in the 54-kDa subunit of the chloroplast signal recognition particle RC Henderson, F Gao, S Jayanthi, A Kight, P Sharma, RL Goforth, ... Biophysical journal 111 (6), 1151-1162, 2016 | 13 | 2016 |