Structure of functionally activated small ribosomal subunit at 3.3 Å resolution F Schluenzen, A Tocilj, R Zarivach, J Harms, M Gluehmann, D Janell, ... cell 102 (5), 615-623, 2000 | 1433 | 2000 |
Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria F Schlünzen, R Zarivach, J Harms, A Bashan, A Tocilj, R Albrecht, ... Nature 413 (6858), 814-821, 2001 | 1385 | 2001 |
High resolution structure of the large ribosomal subunit from a mesophilic eubacterium J Harms, F Schluenzen, R Zarivach, A Bashan, S Gat, I Agmon, H Bartels, ... Cell 107 (5), 679-688, 2001 | 1162 | 2001 |
Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3 M Pioletti, F Schlünzen, J Harms, R Zarivach, M Glühmann, H Avila, ... The EMBO journal, 2001 | 717 | 2001 |
Structural basis for the function of the ribosomal L7/12 stalk in factor binding and GTPase activation M Diaconu, U Kothe, F Schlünzen, N Fischer, JM Harms, AG Tonevitsky, ... Cell 121 (7), 991-1004, 2005 | 488 | 2005 |
The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning DN Wilson, F Schluenzen, JM Harms, AL Starosta, SR Connell, P Fucini Proceedings of the National Academy of Sciences 105 (36), 13339-13344, 2008 | 379 | 2008 |
Structural basis of the ribosomal machinery for peptide bond formation, translocation, and nascent chain progression A Bashan, I Agmon, R Zarivach, F Schluenzen, J Harms, R Berisio, ... Molecular cell 11 (1), 91-102, 2003 | 376 | 2003 |
Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin JM Harms, DN Wilson, F Schluenzen, SR Connell, T Stachelhaus, ... Molecular cell 30 (1), 26-38, 2008 | 350 | 2008 |
X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease S Günther, PYA Reinke, Y Fernández-García, J Lieske, TJ Lane, HM Ginn, ... Science 372 (6542), 642-646, 2021 | 334 | 2021 |
Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin F Schlünzen, E Pyetan, P Fucini, A Yonath, JM Harms Molecular microbiology 54 (5), 1287-1294, 2004 | 314 | 2004 |
Structural basis for the antibiotic activity of ketolides and azalides F Schlünzen, JM Harms, F Franceschi, HAS Hansen, H Bartels, ... Structure 11 (3), 329-338, 2003 | 296 | 2003 |
Structural insight into the role of the ribosomal tunnel in cellular regulation R Berisio, F Schluenzen, J Harms, A Bashan, T Auerbach, D Baram, ... Nature Structural & Molecular Biology 10 (5), 366-370, 2003 | 234 | 2003 |
Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin JM Harms, F Schlünzen, P Fucini, H Bartels, A Yonath BMC biology 2, 1-10, 2004 | 233 | 2004 |
Structural insight into the antibiotic action of telithromycin against resistant mutants R Berisio, J Harms, F Schluenzen, R Zarivach, HAS Hansen, P Fucini, ... Journal of bacteriology 185 (14), 4276-4279, 2003 | 212 | 2003 |
The small ribosomal subunit from Thermus thermophilus at 4.5 Å resolution: Pattern fittings and the identification of a functional site A Tocilj, F Schlünzen, D Janell, M Glühmann, HAS Hansen, J Harms, ... Proceedings of the National Academy of Sciences 96 (25), 14252-14257, 1999 | 171 | 1999 |
The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation F Schluenzen, C Takemoto, DN Wilson, T Kaminishi, JM Harms, ... Nature structural & molecular biology 13 (10), 871-878, 2006 | 157 | 2006 |
X‐ray crystallography study on ribosome recycling: the mechanism of binding and action of RRF on the 50S ribosomal subunit DN Wilson, F Schluenzen, JM Harms, T Yoshida, T Ohkubo, R Albrecht, ... The EMBO journal 24 (2), 251-260, 2005 | 141 | 2005 |
Cryo-EM study of the spinach chloroplast ribosome reveals the structural and functional roles of plastid-specific ribosomal proteins MR Sharma, DN Wilson, PP Datta, C Barat, F Schluenzen, P Fucini, ... Proceedings of the National Academy of Sciences 104 (49), 19315-19320, 2007 | 138 | 2007 |
A snapshot of the 30S ribosomal subunit capturing mRNA via the Shine-Dalgarno interaction T Kaminishi, DN Wilson, C Takemoto, JM Harms, M Kawazoe, ... Structure 15 (3), 289-297, 2007 | 132 | 2007 |
Species-specific antibiotic-ribosome interactions: implications for drug development DN Wilson, JM Harms, KH Nierhaus, F Schlünzen, P Fucini Walter de Gruyter 386 (12), 1239-1252, 2005 | 122 | 2005 |