| Interfacial stress in the development of biologics: fundamental understanding, current practice, and future perspective J Li, ME Krause, X Chen, Y Cheng, W Dai, JJ Hill, M Huang, S Jordan, ... The AAPS journal 21, 1-17, 2019 | 155 | 2019 |
| Overcoming rapid inactivation of lung surfactant: analogies between competitive adsorption and colloid stability JA Zasadzinski, PC Stenger, I Shieh, P Dhar Biochimica et Biophysica Acta (BBA)-Biomembranes 1798 (4), 801-828, 2010 | 109 | 2010 |
| Predicting the agitation-induced aggregation of monoclonal antibodies using surface tensiometry IC Shieh, AR Patel Molecular pharmaceutics 12 (9), 3184-3193, 2015 | 98 | 2015 |
| Linking aggregation and interfacial properties in monoclonal antibody-surfactant formulations A Kannan, IC Shieh, GG Fuller Journal of colloid and interface science 550, 128-138, 2019 | 85 | 2019 |
| A method to measure protein unfolding at an air–liquid interface DL Leiske, IC Shieh, ML Tse Langmuir 32 (39), 9930-9937, 2016 | 82 | 2016 |
| Monoclonal antibody interfaces: dilatation mechanics and bubble coalescence A Kannan, IC Shieh, DL Leiske, GG Fuller Langmuir 34 (2), 630-638, 2018 | 66 | 2018 |
| In-use interfacial stability of monoclonal antibody formulations diluted in saline iv bags A Kannan, IC Shieh, P Hristov, GG Fuller Journal of Pharmaceutical Sciences 110 (4), 1687-1692, 2021 | 39 | 2021 |
| Adsorption and aggregation of monoclonal antibodies at silicone oil–water interfaces A Kannan, IC Shieh, PG Negulescu, V Chandran Suja, GG Fuller Molecular Pharmaceutics 18 (4), 1656-1665, 2021 | 37 | 2021 |
| A comprehensive assessment of all-oleate polysorbate 80: free fatty acid particle formation, interfacial protection and oxidative degradation N Doshi, J Giddings, L Luis, A Wu, K Ritchie, W Liu, W Chan, R Taing, ... Pharmaceutical research 38, 531-548, 2021 | 35 | 2021 |
| Visualizing monolayers with a water-soluble fluorophore to quantify adsorption, desorption, and the double layer IC Shieh, JA Zasadzinski Proceedings of the National Academy of Sciences 112 (8), E826-E835, 2015 | 32 | 2015 |
| Visualizing the Analogy between Competitive Adsorption and Colloid Stability to Restore Lung Surfactant Function IC Shieh, AJ Waring, JA Zasadzinski Biophysical Journal 102 (4), 777-786, 2012 | 12 | 2012 |
| A mechanistic understanding of monoclonal antibody interfacial protection by hydrolytically degraded polysorbate 20 and 80 under IV bag conditions A Kannan, J Giddings, S Mehta, T Lin, A Tomlinson, K Ritchie, I Shieh, ... Pharmaceutical Research 39 (3), 563-575, 2022 | 10 | 2022 |
| A small-scale model to assess the risk of leachables from single-use bioprocess containers through protein quality characterization NJ Xiao, CD Medley, IC Shieh, G Downing, S Pizarro, J Liu, AR Patel PDA Journal of Pharmaceutical Science and Technology 70 (6), 533-546, 2016 | 8 | 2016 |
| Three-dimensional visualization of interfacial phenomena using confocal microscopy IC Shieh University of California, Santa Barbara, 2012 | 3 | 2012 |
| Precipitation Behavior of Highly Soluble Amphiphilic Drugs in Solution: Physical Instability of Drugs in Solution C Hu, JG Napolitano, S Ma, F Hrovat, M Ragains, D Russell, A Kannan, ... Journal of Pharmaceutical Sciences 111 (8), 2172-2179, 2022 | 1 | 2022 |
| Analytical Techniques for Evaluating Protein Instability at Interfaces IC Shieh, Y Cheng Protein Instability at Interfaces During Drug Product Development …, 2021 | 1 | 2021 |
| Evaluation of Interfacial Stress During Drug Product Development ME Krause, S Zheng, IC Shieh, MO Ogunyankin Protein Instability at Interfaces During Drug Product Development …, 2021 | 1 | 2021 |
| Dynamics of interfacial adsorption and self-association of antibody therapeutics IC Shieh, DL Leiske, AR Patel ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 247, 2014 | 1 | 2014 |
| Clinical formulations of anti-tigit antibodies IC Shieh, AM Woys, KL Tschudi, RM Suhling, RS Sane, HMP Chan, ... US Patent App. 18/749,129, 2024 | | 2024 |
| Aggregation Propensities of Monoclonal Antibody Formulations Studied through Interfacial Behavior A Kannan, IC Shieh, G Fuller 2019 AIChE Annual Meeting, 2019 | | 2019 |
