| Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response P Jiang, S Gu, D Pan, J Fu, A Sahu, X Hu, Z Li, N Traugh, X Bu, B Li, J Liu, ... Nature medicine 24 (10), 1550-1558, 2018 | 3795 | 2018 |
| Comprehensive analyses of tumor immunity: implications for cancer immunotherapy B Li, E Severson, JC Pignon, H Zhao, T Li, J Novak, P Jiang, H Shen, ... Genome biology 17, 1-16, 2016 | 2120 | 2016 |
| A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing D Pan, A Kobayashi, P Jiang, L Ferrari de Andrade, RE Tay, AM Luoma, ... Science 359 (6377), 770-775, 2018 | 785 | 2018 |
| Large-scale public data reuse to model immunotherapy response and resistance J Fu, K Li, W Zhang, C Wan, J Zhang, P Jiang, XS Liu Genome medicine 12, 1-8, 2020 | 765 | 2020 |
| SPICi: a fast clustering algorithm for large biological networks P Jiang, M Singh Bioinformatics 26 (8), 1105-1111, 2010 | 279 | 2010 |
| Big data in basic and translational cancer research P Jiang, S Sinha, K Aldape, S Hannenhalli, C Sahinalp, E Ruppin Nature Reviews Cancer 22 (11), 625-639, 2022 | 161 | 2022 |
| Therapeutically increasing MHC-I expression potentiates immune checkpoint blockade SS Gu, W Zhang, X Wang, P Jiang, N Traugh, Z Li, C Meyer, B Stewig, ... Cancer discovery 11 (6), 1524-1541, 2021 | 160 | 2021 |
| Integrin αvβ6–TGFβ–SOX4 pathway drives immune evasion in triple-negative breast cancer A Bagati, S Kumar, P Jiang, J Pyrdol, AE Zou, A Godicelj, ND Mathewson, ... Cancer cell 39 (1), 54-67. e9, 2021 | 154 | 2021 |
| Landscape of B cell immunity and related immune evasion in human cancers X Hu, J Zhang, J Wang, J Fu, T Li, X Zheng, B Wang, S Gu, P Jiang, J Fan, ... Nature genetics 51 (3), 560-567, 2019 | 148 | 2019 |
| Systematic investigation of cytokine signaling activity at the tissue and single-cell levels P Jiang, Y Zhang, B Ru, Y Yang, T Vu, R Paul, A Mirza, G Altan-Bonnet, ... Nature methods 18 (10), 1181-1191, 2021 | 141 | 2021 |
| The Cutoff protein regulates piRNA cluster expression and piRNA production in the Drosophila germline A Pane, P Jiang, DY Zhao, M Singh, T Schüpbach The EMBO journal 30 (22), 4601-4615, 2011 | 136 | 2011 |
| In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target X Wang, C Tokheim, SS Gu, B Wang, Q Tang, Y Li, N Traugh, Z Zeng, ... Cell 184 (21), 5357-5374. e22, 2021 | 131 | 2021 |
| Cistrome cancer: a web resource for integrative gene regulation modeling in cancer S Mei, CA Meyer, R Zheng, Q Qin, Q Wu, P Jiang, B Li, X Shi, B Wang, ... Cancer research 77 (21), e19-e22, 2017 | 128 | 2017 |
| Cytokine and chemokine signals of T-cell exclusion in tumors Y Zhang, X Guan, P Jiang Frontiers in immunology 11, 594609, 2020 | 115 | 2020 |
| MethylPurify: tumor purity deconvolution and differential methylation detection from single tumor DNA methylomes X Zheng, Q Zhao, HJ Wu, W Li, H Wang, CA Meyer, QA Qin, H Xu, C Zang, ... Genome biology 15, 1-13, 2014 | 99 | 2014 |
| Inference of transcriptional regulation in cancers P Jiang, ML Freedman, JS Liu, XS Liu Proceedings of the National Academy of Sciences 112 (25), 7731-7736, 2015 | 98 | 2015 |
| Big data mining yields novel insights on cancer P Jiang, XS Liu Nature genetics 47 (2), 103-104, 2015 | 92 | 2015 |
| Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy T Xiao, W Li, X Wang, H Xu, J Yang, Q Wu, Y Huang, J Geradts, P Jiang, ... Proceedings of the National Academy of Sciences 115 (31), 7869-7878, 2018 | 76 | 2018 |
| Network analysis of gene essentiality in functional genomics experiments P Jiang, H Wang, W Li, C Zang, B Li, YJ Wong, C Meyer, JS Liu, JC Aster, ... Genome biology 16, 1-10, 2015 | 69 | 2015 |
| Functional interactions between microRNAs and RNA binding proteins P Jiang, H Coller MicroRNA 1 (1), 70-79, 2012 | 68 | 2012 |
Xiaole Shirley LiuCEO, GV20 TherapeuticsVerified email at ds.dfci.harvard.edu