Clinical update on head and neck cancer: molecular biology and ongoing challenges TSMT Elham Alsahafi, Katheryn Begg, Ivano Amelio, Nina Raulf, Philippe Lucarelli Cell Death & Diseasevolume 10 (540 (2019)), 2019 | 537 | 2019 |
Downregulation of the TGFβ pseudoreceptor BAMBI in non–small cell lung cancer enhances TGFβ signaling and invasion S Marwitz, S Depner, D Dvornikov, R Merkle, M Szczygieł, ... Cancer research 76 (13), 3785-3801, 2016 | 117 | 2016 |
Cancer cells employ nuclear caspase-8 to overcome the p53-dependent G2/M checkpoint through cleavage of USP28 I Müller, E Strozyk, S Schindler, S Beissert, HZ Oo, T Sauter, P Lucarelli, ... Molecular cell 77 (5), 970-984. e7, 2020 | 75 | 2020 |
Resolving the combinatorial complexity of smad protein complex formation and its link to gene expression P Lucarelli, M Schilling, C Kreutz, A Vlasov, ME Boehm, N Iwamoto, ... Cell systems 6 (1), 75-89. e11, 2018 | 70 | 2018 |
Machine learning-assisted neurotoxicity prediction in human midbrain organoids AS Monzel, K Hemmer, T Kaoma, LM Smits, S Bolognin, P Lucarelli, ... Parkinsonism & Related Disorders 75, 105-109, 2020 | 68 | 2020 |
Annexin A1 regulates EGFR activity and alters EGFR-containing tumour-derived exosomes in head and neck cancers N Raulf, P Lucarelli, S Thavaraj, S Brown, JM Vicencio, T Sauter, ... European Journal of Cancer 102, 52-68, 2018 | 64 | 2018 |
Dynamics and feedback loops in the transforming growth factor β signaling pathway K Wegner, A Bachmann, JU Schad, P Lucarelli, S Sahle, P Nickel, ... Biophysical chemistry 162, 22-34, 2012 | 51 | 2012 |
Context-specific flow through the MEK/ERK module produces cell-and ligand-specific patterns of ERK single and double phosphorylation N Iwamoto, LA D’Alessandro, S Depner, B Hahn, BA Kramer, P Lucarelli, ... Science signaling 9 (413), ra13-ra13, 2016 | 27 | 2016 |
ATG5 and ATG7 expression levels are reduced in cutaneous melanoma and regulated by NRF1 Ž Frangež, D Gérard, Z He, M Gavriil, Y Fernández-Marrero, ... Frontiers in oncology 11, 721624, 2021 | 22 | 2021 |
Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients SL Nickels, J Walter, S Bolognin, D Gérard, C Jaeger, X Qing, J Tisserand, ... Parkinsonism & Related Disorders 67, 48-55, 2019 | 22 | 2019 |
Hypoxia routes tryptophan homeostasis towards increased tryptamine production SR Mohapatra, A Sadik, S Sharma, G Poschet, HM Gegner, TV Lanz, ... Frontiers in immunology 12, 590532, 2021 | 20 | 2021 |
Model based targeting of IL-6-induced inflammatory responses in cultured primary hepatocytes to improve application of the JAK inhibitor ruxolitinib S Sobotta, A Raue, X Huang, J Vanlier, A Jünger, S Bohl, U Albrecht, ... Frontiers in physiology 8, 775, 2017 | 20 | 2017 |
Computational models of melanoma M Albrecht, P Lucarelli, D Kulms, T Sauter Theoretical Biology and Medical Modelling 17, 1-16, 2020 | 17 | 2020 |
FALCON: a toolbox for the fast contextualization of logical networks S De Landtsheer, P Trairatphisan, P Lucarelli, T Sauter Bioinformatics 33 (21), 3431-3436, 2017 | 14 | 2017 |
L-plastin Ser5 phosphorylation is modulated by the PI3K/SGK pathway and promotes breast cancer cell invasiveness RAC Machado, D Stojevski, S De Landtsheer, P Lucarelli, A Baron, ... Cell Communication and Signaling 19, 1-22, 2021 | 12 | 2021 |
Clinical update on head and neck cancer: molecular biology and ongoing challenges. Cell Death Dis. 2019; 10 (8): 540 E Alsahafi, K Begg, I Amelio, N Raulf, P Lucarelli, T Sauter, M Tavassoli | 11 | |
Stroma-induced phenotypic plasticity offers phenotype-specific targeting to improve melanoma treatment K Seip, K Jørgensen, MV Haselager, M Albrecht, MH Haugen, ... Cancer letters 439, 1-13, 2018 | 9 | 2018 |
Using regularization to infer cell line specificity in logical network models of signaling pathways S De Landtsheer, P Lucarelli, T Sauter Frontiers in physiology 9, 550, 2018 | 7 | 2018 |
Systemic network analysis identifies XIAP and IκBα as potential drug targets in TRAIL resistant BRAF mutated melanoma G Del Mistro, P Lucarelli, I Mueller, S De Landtsheer, A Zinoveva, M Hutt, ... NPJ Systems Biology and Applications 4 (1), 39, 2018 | 6 | 2018 |
Excemplify: a flexible template based solution, parsing and managing data in spreadsheets for experimentalists L Shi, L Jong, U Wittig, P Lucarelli, M Stepath, S Mueller, ... Journal of integrative bioinformatics 10 (2), 58-70, 2013 | 6 | 2013 |