Heme induces human and mouse platelet activation through C-type-lectin-like receptor-2 JH Bourne, M Colicchia, Y Di, E Martin, A Slater, LT Roumenina, ... Haematologica 106 (2), 626, 2020 | 75 | 2020 |
S100A8/A9 drives the formation of procoagulant platelets through GPIbα M Colicchia, WC Schrottmaier, G Perrella, JS Reyat, J Begum, A Slater, ... Blood, The Journal of the American Society of Hematology 140 (24), 2626-2643, 2022 | 49 | 2022 |
Does fibrin (ogen) bind to monomeric or dimeric GPVI, or not at all? A Slater, G Perrella, MB Onselaer, EM Martin, JS Gauer, RG Xu, ... Platelets 30 (3), 281-289, 2019 | 42 | 2019 |
GPVI (glycoprotein VI) interaction with fibrinogen is mediated by avidity and the fibrinogen αC-region RG Xu, JS Gauer, SR Baker, A Slater, EM Martin, HR McPherson, C Duval, ... Arteriosclerosis, thrombosis, and vascular biology 41 (3), 1092-1104, 2021 | 31 | 2021 |
Targeting platelet GPVI with glenzocimab: a novel mechanism for inhibition P Billiald, A Slater, M Welin, JC Clark, S Loyau, M Pugnière, IG Jiacomini, ... Blood Advances 7 (7), 1258-1268, 2023 | 30 | 2023 |
Structural characterization of a novel GPVI-nanobody complex reveals a biologically active domain-swapped GPVI dimer A Slater, Y Di, JC Clark, NJ Jooss, EM Martin, F Alenazy, MR Thomas, ... Blood, The Journal of the American Society of Hematology 137 (24), 3443-3453, 2021 | 30 | 2021 |
Factor XII and kininogen asymmetric assembly with gC1qR/C1QBP/P32 is governed by allostery BG Kaira, A Slater, KR McCrae, I Dreveny, U Sumya, NJ Mutch, M Searle, ... Blood, The Journal of the American Society of Hematology 136 (14), 1685-1697, 2020 | 29 | 2020 |
Optimised insert design for improved single-molecule imaging and quantification through CRISPR-Cas9 mediated knock-in AO Khan, CW White, JA Pike, J Yule, A Slater, SJ Hill, NS Poulter, ... Scientific reports 9 (1), 14219, 2019 | 28 | 2019 |
Evidence that GPVI is expressed as a mixture of monomers and dimers, and that the D2 domain is not essential for GPVI activation JC Clark, RAI Neagoe, M Zuidscherwoude, DM Kavanagh, A Slater, ... Thrombosis and Haemostasis 121 (11), 1435-1447, 2021 | 27 | 2021 |
Post-translational polymodification of b1-tubulin regulates motor protein localization in platelet production and function AO Khan, A Slater, A Maclachlan, PLR Nicolson, JA Pike, JS Reyat, ... Haematologica 107 (1), 243, 2020 | 27 | 2020 |
Anti‐GPVI nanobody blocks collagen‐and atherosclerotic plaque–induced GPVI clustering, signaling, and thrombus formation NJ Jooss, CW Smith, A Slater, SJ Montague, Y Di, C O'shea, MR Thomas, ... Journal of Thrombosis and Haemostasis 20 (11), 2617-2631, 2022 | 23 | 2022 |
G-quadruplex ligands mediate downregulation of DUX4 expression L Ciszewski, N Lu-Nguyen, A Slater, A Brennan, HEL Williams, G Dickson, ... Nucleic acids research 48 (8), 4179-4194, 2020 | 23 | 2020 |
Structure-function relationship of the platelet glycoprotein VI (GPVI) receptor: does it matter if it is a dimer or monomer? JC Clark, FN Damaskinaki, YFH Cheung, A Slater, SP Watson Platelets 32 (6), 724-732, 2021 | 20 | 2021 |
Cell receptor and cofactor interactions of the contact activation system and factor XI M Pathak, BG Kaira, A Slater, J Emsley Frontiers in medicine 5, 66, 2018 | 20 | 2018 |
Galectin‐9 activates platelet ITAM receptors glycoprotein VI and C‐type lectin‐like receptor‐2 Z Zhi, NJ Jooss, Y Sun, M Colicchia, A Slater, LA Moran, HYF Cheung, ... Journal of Thrombosis and Haemostasis 20 (4), 936-950, 2022 | 18 | 2022 |
PF4 activates the c-Mpl–Jak2 pathway in platelets RJ Buka, SJ Montague, LA Moran, EM Martin, A Slater, SP Watson, ... Blood 143 (1), 64-69, 2024 | 13 | 2024 |
Role of tyrosine kinase Syk in thrombus stabilisation at high shear G Perrella, SJ Montague, HC Brown, L Garcia Quintanilla, A Slater, ... International journal of molecular sciences 23 (1), 493, 2022 | 13 | 2022 |
Amplified inhibition of atherosclerotic plaque-induced platelet activation by glenzocimab with dual antiplatelet therapy FO Alenazy, MH Harbi, DP Kavanagh, J Price, P Brady, O Hargreaves, ... Journal of Thrombosis and Haemostasis 21 (11), 3236-3251, 2023 | 12 | 2023 |
Platelet activation by charged ligands and nanoparticles: platelet glycoprotein receptors as pattern recognition receptors SJ Montague, P Patel, EM Martin, A Slater, LG Quintanilla, G Perrella, ... Platelets 32 (8), 1018-1030, 2021 | 12 | 2021 |
GPVI inhibition: Advancing antithrombotic therapy in cardiovascular disease A Slater, S Khattak, MR Thomas European Heart Journal-Cardiovascular Pharmacotherapy, pvae018, 2024 | 9 | 2024 |