| TGF-β–induced epithelial-to-mesenchymal transition proceeds through stepwise activation of multiple feedback loops J Zhang, XJ Tian, H Zhang, Y Teng, R Li, F Bai, S Elankumaran, J Xing Science signaling 7 (345), ra91-ra91, 2014 | 521 | 2014 |
| Signal transduction pathways of EMT induced by TGF-β, SHH, and WNT and their crosstalks J Zhang, XJ Tian, J Xing Journal of clinical medicine 5 (4), 41, 2016 | 383 | 2016 |
| Coupled Reversible and Irreversible Bistable Switches Underlying TGFβ-induced Epithelial to Mesenchymal Transition XJ Tian, H Zhang, J Xing Biophysical Journal 105 (4), 1079–1089, 2013 | 305 | 2013 |
| Diabetic kidney diseases revisited: A new perspective for a new era H Fu, S Liu, SI Bastacky, X Wang, XJ Tian, D Zhou Molecular metabolism 30, 250-263, 2019 | 192 | 2019 |
| Interlinking positive and negative feedback loops creates a tunable motif in gene regulatory networks XJ Tian, XP Zhang, F Liu, W Wang Physical Review E—Statistical, Nonlinear, and Soft Matter Physics 80 (1 …, 2009 | 128 | 2009 |
| Epigenetic state network approach for describing cell phenotypic transitions P Wang, C Song, H Zhang, Z Wu, XJ Tian, J Xing Interface focus 4 (3), 20130068, 2014 | 64 | 2014 |
| Winner-takes-all resource competition redirects cascading cell fate transitions R Zhang, H Goetz, J Melendez-Alvarez, J Li, T Ding, X Wang, XJ Tian Nature communications 12 (1), 853, 2021 | 63 | 2021 |
| Fibroblast-specific β-catenin signaling dictates the outcome of AKI D Zhou, H Fu, L Xiao, H Mo, H Zhuo, X Tian, L Lin, J Xing, Y Liu Journal of the American Society of Nephrology 29 (4), 1257-1271, 2018 | 62 | 2018 |
| Topology-dependent interference of synthetic gene circuit function by growth feedback R Zhang, J Li, J Melendez-Alvarez, X Chen, P Sochor, H Goetz, Q Zhang, ... Nature chemical biology 16 (6), 695-701, 2020 | 61 | 2020 |
| Statistical mechanics model for the dynamics of collective epigenetic histone modification H Zhang, XJ Tian, A Mukhopadhyay, KS Kim, J Xing Physical review letters 112 (6), 068101, 2014 | 60 | 2014 |
| Serum integrative omics reveals the landscape of human diabetic kidney disease S Liu, Y Gui, MS Wang, L Zhang, T Xu, Y Pan, K Zhang, Y Yu, L Xiao, ... Molecular metabolism 54, 101367, 2021 | 54 | 2021 |
| Novel antibacterial modalities against methicillin resistant Staphylococcus aureus derived from plants J Li, D Liu, X Tian, S Koseki, S Chen, X Ye, T Ding Critical reviews in food science and nutrition 59 (sup1), S153-S161, 2019 | 47 | 2019 |
| A plausible accelerating function of intermediate states in cancer metastasis H Goetz, JR Melendez-Alvarez, L Chen, XJ Tian PLoS computational biology 16 (3), e1007682, 2020 | 40 | 2020 |
| A two-step mechanism for cell fate decision by coordination of nuclear and mitochondrial p53 activities XJ Tian, F Liu, XP Zhang, J Li, W Wang PloS one 7 (6), e38164, 2012 | 38 | 2012 |
| Investigating epithelial-to-mesenchymal transition with integrated computational and experimental approaches J Xing, XJ Tian Physical biology, 2019 | 34 | 2019 |
| Tumor-specific chromosome mis-segregation controls cancer plasticity by maintaining tumor heterogeneity Y Hu, N Ru, H Xiao, A Chaturbedi, NT Hoa, XJ Tian, H Zhang, C Ke, ... PLoS One 8 (11), e80898, 2013 | 33 | 2013 |
| Pathway crosstalk enables cells to interpret TGF-β duration J Zhang, XJ Tian, YJ Chen, W Wang, S Watkins, J Xing NPJ systems biology and applications 4 (1), 18, 2018 | 31 | 2018 |
| Achieving diverse and monoallelic olfactory receptor selection through dual-objective optimization design XJ Tian, H Zhang, J Sannerud, J Xing Proceedings of the National Academy of Sciences 113 (21), E2889-E2898, 2016 | 31 | 2016 |
| Leveraging an established neighbourhood-level, open access wastewater monitoring network to address public health priorities: a population-based study DA Bowes, EM Driver, S Kraberger, RS Fontenele, LRA Holland, J Wright, ... The Lancet Microbe 4 (1), e29-e37, 2023 | 24 | 2023 |
| Reciprocal regulation between mRNA and microRNA enables a bistable switch that directs cell fate decisions XJ Tian, H Zhang, J Zhang, J Xing FEBS letters 590 (19), 3443-3455, 2016 | 23 | 2016 |
Jianhua XingProfessor, Department of Computational and Systems Biology, University of PittsburghVerified email at pitt.edu