3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV–infected mice AD Rathnayake, J Zheng, Y Kim, KD Perera, S Mackin, DK Meyerholz, ... Science translational medicine 12 (557), eabc5332, 2020 | 247 | 2020 |
Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection CS Dampalla, J Zheng, KD Perera, LYR Wong, DK Meyerholz, ... Proceedings of the National Academy of Sciences 118 (29), e2101555118, 2021 | 86 | 2021 |
Protease inhibitors broadly effective against feline, ferret and mink coronaviruses KD Perera, ACG Kankanamalage, AD Rathnayake, A Honeyfield, ... Antiviral research 160, 79-86, 2018 | 44 | 2018 |
Characterization of amino acid substitutions in feline coronavirus 3C-like protease from a cat with feline infectious peritonitis treated with a protease inhibitor KD Perera, AD Rathnayake, H Liu, NC Pedersen, WC Groutas, KO Chang, ... Veterinary microbiology 237, 108398, 2019 | 39 | 2019 |
Structure-guided design of potent inhibitors of SARS-CoV-2 3CL protease: structural, biochemical, and cell-based studies CS Dampalla, AD Rathnayake, KD Perera, ARM Jesri, HN Nguyen, ... Journal of medicinal chemistry 64 (24), 17846-17865, 2021 | 36 | 2021 |
Effects of spike mutations in SARS-CoV-2 variants of concern on human or animal ACE2-mediated virus entry and neutralization Y Kim, NN Gaudreault, DA Meekins, KD Perera, D Bold, JD Trujillo, ... Microbiology Spectrum 10 (3), e01789-21, 2022 | 35 | 2022 |
Structure-guided design of potent spirocyclic inhibitors of severe acute respiratory syndrome coronavirus-2 3C-like protease CS Dampalla, AD Rathnayake, AC Galasiti Kankanamalage, Y Kim, ... Journal of Medicinal Chemistry 65 (11), 7818-7832, 2022 | 30 | 2022 |
Interactions of viruses and the humoral innate immune response BE Maloney, KD Perera, DRD Saunders, N Shadipeni, SD Fleming Clinical immunology 212, 108351, 2020 | 28 | 2020 |
SARS-CoV-2 Omicron (B. 1.1. 529) infection of wild white-tailed deer in New York City KJ Vandegrift, M Yon, M Surendran Nair, A Gontu, S Ramasamy, ... Viruses 14 (12), 2770, 2022 | 23 | 2022 |
Broad-spectrum cyclopropane-based inhibitors of coronavirus 3C-like proteases: biochemical, structural, and virological studies CS Dampalla, HN Nguyen, AD Rathnayake, Y Kim, KD Perera, ... ACS Pharmacology & Translational Science 6 (1), 181-194, 2022 | 12 | 2022 |
The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2 R Huang, G Warner Jenkins, Y Kim, RL Stanfield, A Singh, ... Proceedings of the National Academy of Sciences 120 (39), e2303455120, 2023 | 11 | 2023 |
3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice. Sci Transl Med 12: eabc5332 AD Rathnayake, J Zheng, Y Kim, KD Perera, S Mackin, DK Meyerholz, ... | 9 | 2020 |
3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice. Sci Transl Med. 2020; 12 (557) AD Rathnayake, J Zheng, Y Kim, KD Perera, S Mackin, DK Meyerholz, ... Epub 2020/08/05. doi: 10.1126/scitranslmed. abc5332. PubMed PMID: 32747425, 0 | 6 | |
Potent protease inhibitors of highly pathogenic lagoviruses: rabbit hemorrhagic disease virus and European brown hare syndrome virus KD Perera, D Johnson, S Lovell, WC Groutas, KO Chang, Y Kim Microbiology Spectrum 10 (4), e00142-22, 2022 | 5 | 2022 |
Potent protease inhibitors of deadly lagoviruses: rabbit hemorrhagic disease virus and European brown hare syndrome virus KD Perera, D Johnson, S Lovell, W Groutas, KO Chang, Y Kim bioRxiv, 2022.01. 10.474982, 2022 | | 2022 |
Studies of viral entry and viral proteases of coronaviruses and caliciviruses KDI Perera Kansas State University, 2022 | | 2022 |
3C-like protease inhibitors against coronaviruses KDI Perera | | 2018 |