| Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation E Matsa, D Rajamohan, E Dick, L Young, I Mellor, A Staniforth, C Denning European heart journal 32 (8), 952-962, 2011 | 479 | 2011 |
| Small molecule absorption by PDMS in the context of drug response bioassays BJ Van Meer, H de Vries, KSA Firth, J van Weerd, LGJ Tertoolen, ... Biochemical and biophysical research communications 482 (2), 323-328, 2017 | 456 | 2017 |
| Deletion of the α (1, 3) galactosyl transferase (GGTA1) gene and the prion protein (PrP) gene in sheep C Denning, S Burl, A Ainslie, J Bracken, A Dinnyes, J Fletcher, T King, ... Nature biotechnology 19 (6), 559-562, 2001 | 383 | 2001 |
| Improved human embryonic stem cell embryoid body homogeneity and cardiomyocyte differentiation from a novel V-96 plate aggregation system highlights interline variability PW Burridge, D Anderson, H Priddle, MD Barbadillo Muñoz, ... Stem Cells 25 (4), 929-938, 2007 | 376 | 2007 |
| Cardiomyocytes from human pluripotent stem cells: from laboratory curiosity to industrial biomedical platform C Denning, V Borgdorff, J Crutchley, KSA Firth, V George, S Kalra, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (7), 1728-1748, 2016 | 356 | 2016 |
| MUSCLEMOTION: a versatile open software tool to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo L Sala, BJ Van Meer, LGJ Tertoolen, J Bakkers, M Bellin, RP Davis, ... Circulation research 122 (3), e5-e16, 2018 | 339 | 2018 |
| Transgenic enrichment of cardiomyocytes from human embryonic stem cells D Anderson, T Self, IR Mellor, G Goh, SJ Hill, C Denning Molecular Therapy 15 (11), 2027-2036, 2007 | 281 | 2007 |
| CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for … D Mosqueira, I Mannhardt, JR Bhagwan, K Lis-Slimak, P Katili, E Scott, ... European heart journal 39 (43), 3879-3892, 2018 | 252 | 2018 |
| N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells A Abakir, TC Giles, A Cristini, JM Foster, N Dai, M Starczak, ... Nature genetics 52 (1), 48-55, 2020 | 207 | 2020 |
| Restriction landmark genome scanning identifies culture-induced DNA methylation instability in the human embryonic stem cell epigenome C Allegrucci, YZ Wu, A Thurston, CN Denning, H Priddle, CL Mummery, ... Human molecular genetics 16 (10), 1253-1268, 2007 | 205 | 2007 |
| Materials for stem cell factories of the future AD Celiz, JGW Smith, R Langer, DG Anderson, DA Winkler, DA Barrett, ... Nature materials 13 (6), 570-579, 2014 | 183 | 2014 |
| Automated, scalable culture of human embryonic stem cells in feeder‐free conditions RJ Thomas, D Anderson, A Chandra, NM Smith, LE Young, D Williams, ... Biotechnology and Bioengineering 102 (6), 1636-1644, 2009 | 183 | 2009 |
| Complex relationship between cardiac fibroblasts and cardiomyocytes in health and disease C Hall, K Gehmlich, C Denning, D Pavlovic Journal of the American Heart Association 10 (5), e019338, 2021 | 168 | 2021 |
| Allele-specific RNA interference rescues the long-QT syndrome phenotype in human-induced pluripotency stem cell cardiomyocytes E Matsa, JE Dixon, C Medway, O Georgiou, MJ Patel, K Morgan, PJ Kemp, ... European heart journal 35 (16), 1078-1087, 2014 | 152 | 2014 |
| Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage Nature biotechnology 29 (12), 1132-1144, 2011 | 148 | 2011 |
| Bystander effects of different enzyme-prodrug systems for cancer gene therapy depend on different pathways for intercellular transfer of toxic metabolites, a factor that will … C Denning, JD Pitts Human gene therapy 8 (15), 1825-1835, 1997 | 140 | 1997 |
| Modeling and study of the mechanism of dilated cardiomyopathy using induced pluripotent stem cells derived from individuals with Duchenne muscular dystrophy B Lin, Y Li, L Han, AD Kaplan, Y Ao, S Kalra, GCL Bett, RL Rasmusson, ... Disease models & mechanisms 8 (5), 457-466, 2015 | 134 | 2015 |
| Current status of drug screening and disease modelling in human pluripotent stem cells D Rajamohan, E Matsa, S Kalra, J Crutchley, A Patel, V George, ... Bioessays 35 (3), 281-298, 2013 | 130 | 2013 |
| Notch signaling deficiency underlies age-dependent depletion of satellite cells in muscular dystrophy C Jiang, Y Wen, K Kuroda, K Hannon, MA Rudnicki, S Kuang Disease models & mechanisms 7 (8), 997-1004, 2014 | 129 | 2014 |
| Evaluating the utility of cardiomyocytes from human pluripotent stem cells for drug screening E Dick, D Rajamohan, J Ronksley, C Denning Biochemical Society Transactions 38 (4), 1037-1045, 2010 | 129 | 2010 |
