| Systems‐level interactions between insulin–EGF networks amplify mitogenic signaling N Borisov, E Aksamitiene, A Kiyatkin, S Legewie, J Berkhout, T Maiwald, ... Molecular systems biology 5 (1), 256, 2009 | 281 | 2009 |
| Scaffolding protein Grb2-associated binder 1 sustains epidermal growth factor-induced mitogenic and survival signaling by multiple positive feedback loops A Kiyatkin, E Aksamitiene, NI Markevich, NM Borisov, JB Hoek, ... Journal of biological chemistry 281 (29), 19925-19938, 2006 | 245 | 2006 |
| In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development IV Ozerov, KV Lezhnina, E Izumchenko, AV Artemov, S Medintsev, ... Nature communications 7 (1), 13427, 2016 | 161 | 2016 |
| Signaling through receptors and scaffolds: independent interactions reduce combinatorial complexity NM Borisov, NI Markevich, JB Hoek, BN Kholodenko Biophysical journal 89 (2), 951-966, 2005 | 132 | 2005 |
| Oncofinder, a new method for the analysis of intracellular signaling pathway activation using transcriptomic data AA Buzdin, AA Zhavoronkov, MB Korzinkin, LS Venkova, AA Zenin, ... Frontiers in genetics 5, 55, 2014 | 115 | 2014 |
| Molecular pathway activation–new type of biomarkers for tumor morphology and personalized selection of target drugs A Buzdin, M Sorokin, A Garazha, M Sekacheva, E Kim, N Zhukov, Y Wang, ... Seminars in cancer biology 53, 110-124, 2018 | 94 | 2018 |
| Signaling pathways activation profiles make better markers of cancer than expression of individual genes NM Borisov, NV Terekhanova, AM Aliper, LS Venkova, PY Smirnov, ... Oncotarget 5 (20), 10198, 2014 | 86 | 2014 |
| Silencing AML1-ETO gene expression leads to simultaneous activation of both pro-apoptotic and proliferation signaling PV Spirin, TD Lebedev, NN Orlova, AS Gornostaeva, MM Prokofjeva, ... Leukemia 28 (11), 2222-2228, 2014 | 85 | 2014 |
| Domain-oriented reduction of rule-based network models NM Borisov, AS Chistopolsky, JR Faeder, BN Kholodenko IET systems biology 2 (5), 342-351, 2008 | 74 | 2008 |
| In search for geroprotectors: in silico screening and in vitro validation of signalome-level mimetics of young healthy state. ZA Aliper A, Belikov AV, Garazha A, Jellen L, Artemov A, Suntsova M, Ivanova ... Aging (Albany NY), 2016 | 68 | 2016 |
| Data aggregation at the level of molecular pathways improves stability of experimental transcriptomic and proteomic data N Borisov, M Suntsova, M Sorokin, A Garazha, O Kovalchuk, A Aliper, ... Cell cycle 16 (19), 1810-1823, 2017 | 67 | 2017 |
| Quantitation of molecular pathway activation using RNA sequencing data N Borisov, M Sorokin, A Garazha, A Buzdin Nucleic Acid Detection and Structural Investigations: Methods and Protocols …, 2020 | 66 | 2020 |
| A method of gene expression data transfer from cell lines to cancer patients for machine-learning prediction of drug efficiency N Borisov, V Tkachev, M Suntsova, O Kovalchuk, A Zhavoronkov, ... Cell Cycle 17 (4), 486-491, 2018 | 65 | 2018 |
| The OncoFinder algorithm for minimizing the errors introduced by the high-throughput methods of transcriptome analysis AA Buzdin, AA Zhavoronkov, MB Korzinkin, SA Roumiantsev, AM Aliper, ... Frontiers in Molecular Biosciences 1, 8, 2014 | 65 | 2014 |
| A method for predicting target drug efficiency in cancer based on the analysis of signaling pathway activation A Artemov, A Aliper, M Korzinkin, K Lezhnina, L Jellen, N Zhukov, ... Oncotarget 6 (30), 29347, 2015 | 64 | 2015 |
| Signaling pathway cloud regulation for in silico screening and ranking of the potential geroprotective drugs A Zhavoronkov, AA Buzdin, AV Garazha, NM Borisov, AA Moskalev Frontiers in genetics 5, 49, 2014 | 61 | 2014 |
| Trading the micro-world of combinatorial complexity for the macro-world of protein interaction domains NM Borisov, NI Markevich, JB Hoek, BN Kholodenko Biosystems 83 (2-3), 152-166, 2006 | 60 | 2006 |
| A new graphical user interface for fast construction of computation phantoms and MCNP calculations: application to calibration of in vivo measurement systems N Borisov, D Franck, L De Carlan, L Laval Health physics 83 (2), 272-279, 2002 | 59 | 2002 |
| Algorithmic annotation of functional roles for components of 3,044 human molecular pathways M Sorokin, N Borisov, D Kuzmin, A Gudkov, M Zolotovskaia, A Garazha, ... Frontiers in genetics 12, 617059, 2021 | 55 | 2021 |
| Novel robust biomarkers for human bladder cancer based on activation of intracellular signaling pathways K Lezhnina, O Kovalchuk, AA Zhavoronkov, MB Korzinkin, ... Oncotarget 5 (19), 9022, 2014 | 55 | 2014 |
Anton BuzdinChief Scientific Officer, PhDVerified email at oncobox.com