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A quantitative tissue-specific landscape of protein redox regulation during aging H Xiao, MP Jedrychowski, DK Schweppe, EL Huttlin, Q Yu, DE Heppner, ... Cell 180 (5), 968-983. e24, 2020 | 317 | 2020 |
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Discovery and Identification of Small Molecules as Methuosis Inducers with in Vivo Antitumor Activities W Huang, X Sun, Y Li, Z He, L Li, Z Deng, X Huang, S Han, T Zhang, ... Journal of medicinal chemistry 61 (12), 5424-5434, 2018 | 48 | 2018 |
Covalent disruptor of YAP-TEAD association suppresses defective Hippo signaling M Fan, W Lu, J Che, NP Kwiatkowski, Y Gao, HS Seo, SB Ficarro, ... Elife 11, e78810, 2022 | 46 | 2022 |
Discovery of MFH290: a potent and highly selective covalent inhibitor for cyclin-dependent kinase 12/13 Y Liu, M Hao, AL Leggett, Y Gao, SB Ficarro, J Che, Z He, CM Olson, ... Journal of Medicinal Chemistry 63 (13), 6708-6726, 2020 | 36 | 2020 |
Targeting BRK-positive breast cancers with small-molecule kinase inhibitors J Jiang, F Gui, Z He, L Li, Y Li, S Li, X Wu, Z Deng, X Sun, X Huang, ... Cancer research 77 (1), 175-186, 2017 | 29 | 2017 |
A non‐covalent inhibitor XMU‐MP‐3 overrides ibrutinib‐resistant BtkC481S mutation in B‐cell malignancies F Gui, J Jiang, Z He, L Li, Y Li, Z Deng, Y Lu, X Wu, G Chen, J Su, S Song, ... British Journal of Pharmacology 176 (23), 4491-4509, 2019 | 21 | 2019 |
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Development of a covalent inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1 W Lu, Y Liu, Y Gao, Q Geng, D Gurbani, L Li, SB Ficarro, CJ Meyer, ... Journal of Medicinal Chemistry 66 (5), 3356-3371, 2023 | 13 | 2023 |
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New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation ML Arwood, Y Liu, SK Harkins, DM Weinstock, L Yang, KE Stevenson, ... Cell chemical biology 30 (6), 618-631. e12, 2023 | 3 | 2023 |
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