Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation CMT Spahn, MG Gomez‐Lorenzo, RA Grassucci, R Jørgensen, ... The EMBO journal 23 (5), 1008-1019, 2004 | 513 | 2004 |
(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium MB Jiménez-Díaz, D Ebert, Y Salinas, A Pradhan, AM Lehane, ... Proceedings of the National Academy of Sciences 111 (50), E5455-E5462, 2014 | 290 | 2014 |
Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics AN Cowell, ES Istvan, AK Lukens, MG Gomez-Lorenzo, M Vanaerschot, ... Science 359 (6372), 191-199, 2018 | 251 | 2018 |
Three‐dimensional cryo‐electron microscopy localization of EF2 in the Saccharomyces cerevisiae 80S ribosome at 17.5 Å resolution MG Gomez‐Lorenzo, CMT Spahn, RK Agrawal, RA Grassucci, P Penczek, ... The EMBO journal, 2000 | 202 | 2000 |
A broad analysis of resistance development in the malaria parasite VC Corey, AK Lukens, ES Istvan, MCS Lee, V Franco, P Magistrado, ... Nature communications 7 (1), 11901, 2016 | 131 | 2016 |
Large T antigen on the simian virus 40 origin of replication: a 3D snapshot prior to DNA replication MG Gomez‐Lorenzo, M Valle, J Frank, C Gruss, COS Sorzano, XS Chen, ... The EMBO journal, 2003 | 95 | 2003 |
Sordarin inhibits fungal protein synthesis by blocking translocation differently to fusidic acid JM Domı́nguez, MG Gómez-Lorenzo, JJ Martı́n Journal of Biological Chemistry 274 (32), 22423-22427, 1999 | 80 | 1999 |
Ribosomal P-protein stalk function is targeted by sordarin antifungals MG Gómez-Lorenzo, JF Garcı́a-Bustos Journal of Biological Chemistry 273 (39), 25041-25044, 1998 | 62 | 1998 |
Identifying rapidly parasiticidal anti-malarial drugs using a simple and reliable in vitro parasite viability fast assay M Linares, S Viera, B Crespo, V Franco, MG Gómez-Lorenzo, ... Malaria journal 14, 1-8, 2015 | 60 | 2015 |
Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum K Kümpornsin, T Kochakarn, T Yeo, J Okombo, MR Luth, J Hoshizaki, ... Nature Communications 14 (1), 3059, 2023 | 27 | 2023 |
In vitro models for human malaria: targeting the liver stage AL Valenciano, MG Gomez-Lorenzo, J Vega-Rodríguez, JH Adams, ... Trends in parasitology 38 (9), 758-774, 2022 | 26 | 2022 |
The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance JM Murithi, I Deni, CFA Pasaje, J Okombo, JL Bridgford, NF Gnädig, ... Cell chemical biology 29 (5), 824-839. e6, 2022 | 21 | 2022 |
Efforts aimed to reduce attrition in antimalarial drug discovery: a systematic evaluation of the current antimalarial targets portfolio MJ Chaparro, F Calderón, P Castañeda, E Fernández-Alvaro, R Gabarró, ... ACS Infectious Diseases 4 (4), 568-576, 2018 | 20 | 2018 |
Autophagy in PDGFRα+ mesenchymal cells is essential for intestinal stem cell survival Y Yang, M Gomez, T Marsh, L Poillet-Perez, A Sawant, L Chen, NR Park, ... Proceedings of the National Academy of Sciences 119 (21), e2202016119, 2022 | 16 | 2022 |
Functional screening of selective mitochondrial inhibitors of Plasmodium MG Gomez-Lorenzo, A Rodríguez-Alejandre, S Moliner-Cubel, ... International Journal for Parasitology: Drugs and Drug Resistance 8 (2), 295-303, 2018 | 16 | 2018 |
Development of two novel high-throughput assays to quantify ubiquitylated proteins in cell lysates: application to screening of new anti-malarials L Mata-Cantero, C Cid, MG Gomez-Lorenzo, W Xolalpa, F Aillet, JJ Martín, ... Malaria Journal 14, 1-16, 2015 | 16 | 2015 |
Ozonoterapia analgésica R Wong, A Ceballos, S Menéndez, H Gómez Revista CENIC Ciencias Biológicas 20 (1-2-3), 139-144, 1989 | 15 | 1989 |
Tratamiento de la osteoartritis con ozono A Ceballos, R Balmaseda, R Wong, S Menéndez, H Gómez Revista CENIC Ciencias Biológicas 20 (1-2-3), 151-153, 1989 | 14 | 1989 |
Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target ES Istvan, F Guerra, M Abraham, KS Huang, F Rocamora, H Zhao, L Xu, ... Science translational medicine 15 (686), eadc9249, 2023 | 12 | 2023 |
Lumefantrine attenuates Plasmodium falciparum artemisinin resistance during the early ring stage K Kümpornsin, D Loesbanluechai, C de Cozar, N Kotanan, K Chotivanich, ... International Journal for Parasitology: Drugs and Drug Resistance 17, 186-190, 2021 | 12 | 2021 |