Coronavirus nonstructural protein 15 mediates evasion of dsRNA sensors and limits apoptosis in macrophages X Deng, M Hackbart, RC Mettelman, A O’Brien, AM Mielech, G Yi, CC Kao, ... Proceedings of the National Academy of Sciences 114 (21), E4251-E4260, 2017 | 413 | 2017 |
SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans PA Mudd, AA Minervina, MV Pogorelyy, JS Turner, W Kim, E Kalaidina, ... Cell 185 (4), 603-613. e15, 2022 | 263 | 2022 |
SARS-CoV-2 antigen exposure history shapes phenotypes and specificity of memory CD8+ T cells AA Minervina, MV Pogorelyy, AM Kirk, JC Crawford, EK Allen, CH Chou, ... Nature immunology 23 (5), 781-790, 2022 | 173 | 2022 |
Mucosal immune responses to infection and vaccination in the respiratory tract RC Mettelman, EK Allen, PG Thomas Immunity 55 (5), 749-780, 2022 | 161 | 2022 |
Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response CY Lin, J Wolf, DC Brice, Y Sun, M Locke, S Cherry, AH Castellaw, ... Cell Host & Microbe 30 (1), 83-96. e4, 2022 | 90 | 2022 |
The papain-like protease determines a virulence trait that varies among members of the SARS-coronavirus species D Niemeyer, K Mösbauer, EM Klein, A Sieberg, RC Mettelman, ... PLoS pathogens 14 (9), e1007296, 2018 | 77 | 2018 |
X-ray structure and enzymatic activity profile of a core papain-like protease of MERS coronavirus with utility for structure-based drug design JR Clasman, YM Báez-Santos, RC Mettelman, A o’Brien, SC Baker, ... Scientific Reports 7 (1), 40292, 2017 | 54 | 2017 |
The unappreciated intracellular lifestyle of Blastomyces dermatitidis AK Sterkel, R Mettelman, M Wüthrich, BS Klein The Journal of Immunology 194 (4), 1796-1805, 2015 | 43 | 2015 |
Common Trajectories of Highly Effective CD19-Specific CAR T Cells Identified by Endogenous T-cell Receptor Lineages TL Wilson, H Kim, CH Chou, D Langfitt, RC Mettelman, AA Minervina, ... Cancer Discovery 12 (9), 2098-2119, 2022 | 42 | 2022 |
Baseline innate and T cell populations are correlates of protection against symptomatic influenza virus infection independent of serology RC Mettelman, A Souquette, LA Van de Velde, K Vegesana, EK Allen, ... Nature immunology 24 (9), 1511-1526, 2023 | 38 | 2023 |
Resolving SARS-CoV-2 CD4+ T cell specificity via reverse epitope discovery MV Pogorelyy, E Rosati, AA Minervina, RC Mettelman, A Scheffold, ... Cell Reports Medicine 3 (8), 2022 | 37 | 2022 |
Analysis of coronavirus temperature-sensitive mutants reveals an interplay between the macrodomain and papain-like protease impacting replication and pathogenesis X Deng, RC Mettelman, A O’Brien, JA Thompson, TE O’Brien, SC Baker Journal of virology 93 (12), 10.1128/jvi. 02140-18, 2019 | 37 | 2019 |
Structure-guided mutagenesis alters deubiquitinating activity and attenuates pathogenesis of a murine coronavirus X Deng, Y Chen, AM Mielech, M Hackbart, KR Kesely, RC Mettelman, ... Journal of virology 94 (11), 10.1128/jvi. 01734-19, 2020 | 34 | 2020 |
Human susceptibility to influenza infection and severe disease RC Mettelman, PG Thomas Cold Spring Harbor Perspectives in Medicine 11 (5), a038711, 2021 | 23 | 2021 |
Characterizing replication kinetics and plaque production of type I feline infectious peritonitis virus in three feline cell lines A O’Brien, RC Mettelman, A Volk, NM André, GR Whittaker, SC Baker Virology 525, 1-9, 2018 | 17 | 2018 |
Molecular mimicry in multisystem inflammatory syndrome in children A Bodansky, RC Mettelman, JJ Sabatino Jr, SE Vazquez, J Chou, ... Nature 632 (8025), 622-629, 2024 | 12 | 2024 |
Generating and evaluating type I interferon receptor-deficient and feline TMPRSS2-expressing cells for propagating serotype I feline infectious peritonitis virus RC Mettelman, A O'Brien, GR Whittaker, SC Baker Virology 537, 226-236, 2019 | 8 | 2019 |
High expression of oleoyl-ACP hydrolase underpins life-threatening respiratory viral diseases X Jia, JC Crawford, D Gebregzabher, EA Monson, RC Mettelman, Y Wan, ... Cell 187 (17), 4586-4604. e20, 2024 | 5 | 2024 |
Utility of nasal swabs for assessing mucosal immune responses towards SARS-CoV-2 EK Roubidoux, PH Brigleb, K Vegesana, A Souquette, K Whitt, P Freiden, ... Scientific Reports 13 (1), 17820, 2023 | 5 | 2023 |
An adaptive, asymptomatic SARS-CoV-2 workforce screening program providing real-time, actionable monitoring of the COVID-19 pandemic DR Hijano, JM Hoffman, L Tang, SL Schultz-Cherry, PG Thomas, H Hakim, ... Plos one 17 (5), e0268237, 2022 | 5 | 2022 |