| ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF-and IFNγ-driven immunopathology R Gawish, P Starkl, L Pimenov, A Hladik, K Lakovits, F Oberndorfer, ... Elife 11, e74623, 2022 | 53 | 2022 |
| Simulation of reversible protein–protein binding and calculation of binding free energies using perturbed distance restraints JW Perthold, C Oostenbrink Journal of chemical theory and computation 13 (11), 5697-5708, 2017 | 42 | 2017 |
| Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptor T Capraz, NF Kienzl, E Laurent, JW Perthold, E Föderl-Höbenreich, ... Elife 10, e73641, 2021 | 34 | 2021 |
| Accelerated enveloping distribution sampling: Enabling sampling of multiple end states while preserving local energy minima JW Perthold, C Oostenbrink The Journal of Physical Chemistry B 122 (19), 5030-5037, 2018 | 34 | 2018 |
| Toward automated free energy calculation with accelerated enveloping distribution sampling (A-EDS) JW Perthold, D Petrov, C Oostenbrink Journal of Chemical Information and Modeling 60 (11), 5395-5406, 2020 | 27 | 2020 |
| Charge-changing perturbations and path sampling via classical molecular dynamic simulations of simple guest–host systems C Öhlknecht, JW Perthold, B Lier, C Oostenbrink Journal of Chemical Theory and Computation 16 (12), 7721-7734, 2020 | 19 | 2020 |
| Designing Fcabs: well-expressed and stable high affinity antigen-binding Fc fragments G Wozniak-Knopp, G Stadlmayr, JW Perthold, K Stadlbauer, ... Protein Engineering, Design and Selection 30 (9), 657-671, 2017 | 16 | 2017 |
| GroScore: accurate scoring of protein–protein binding poses using explicit-solvent free-energy calculations JW Perthold, C Oostenbrink Journal of Chemical Information and Modeling 59 (12), 5074-5085, 2019 | 14 | 2019 |
| An antibody with Fab-constant domains exchanged for a pair of CH3 domains G Wozniak-Knopp, G Stadlmayr, JW Perthold, K Stadlbauer, M Gotsmy, ... PLoS One 13 (4), e0195442, 2018 | 12 | 2018 |
| Guidelines for Free-Energy Calculations Involving Charge Changes D Petrov, JW Perthold, C Oostenbrink, BL de Groot, V Gapsys Journal of Chemical Theory and Computation 20 (2), 914-925, 2024 | 9 | 2024 |
| Simulation of Reversible Protein-Protein Binding at an Atomistic Scale JW Perthold, C Oehlknecht, D Petrov, C Oostenbrink EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 48, S195-S195, 2019 | | 2019 |
| Domain-exchanged antibody with potentiated effector functions GW Knopp, G Stadlmayr, JW Perthold, K Stadlbauer, F Rueker New Biotechnology, S47, 2016 | | 2016 |
| ACE2 is the critical in vivo receptor for SARS-CoV-2 in a novel COVID-19 mouse model with TNF-and IFN?-driven immunopathology R Gawish, B Agerer, L Endler, T Capraz, JW Perthold, D Cikes, ... eLife Sciences Publications Limited, 0 | | |