| Animal models of fulminant hepatic failure: a critical evaluation PN Newsome, JN Plevris, LJ Nelson, PC Hayes Liver Transplantation 6 (1), 21-31, 2000 | 192 | 2000 |
| Alcoholic liver disease: Utility of animal models A Lamas-Paz, F Hao, LJ Nelson, MT Vázquez, S Canals, MG Del Moral, ... World journal of gastroenterology 24 (45), 5063, 2018 | 177 | 2018 |
| Dissecting the molecular pathophysiology of drug-induced liver injury H Ye, LJ Nelson, MG Del Moral, E Martínez-Naves, FJ Cubero World journal of gastroenterology 24 (13), 1373, 2018 | 162 | 2018 |
| Which hepatocyte will it be? Hepatocyte choice for bioartificial liver support systems J Tsiaoussis, PN Newsome, LJ Nelson, PC Hayes, JN Plevris Liver Transplantation 7 (1), 2-10, 2001 | 140 | 2001 |
| Reclassifying hepatic cell death during liver damage: ferroptosis—a novel form of non-apoptotic cell death? RU Macías-Rodríguez, ME Inzaugarat, A Ruiz-Margáin, LJ Nelson, ... International journal of molecular sciences 21 (5), 1651, 2020 | 94 | 2020 |
| Advanced preclinical models for evaluation of drug-induced liver injury–consensus statement by the European Drug-Induced Liver Injury Network [PRO-EURO-DILI-NET] JC Fernandez-Checa, P Bagnaninchi, H Ye, P Sancho-Bru, ... Journal of Hepatology 75 (4), 935-959, 2021 | 89 | 2021 |
| Improvement of C3A cell metabolism for usage in bioartificial liver support systems C Filippi, SA Keatch, D Rangar, LJ Nelson, PC Hayes, JN Plevris Journal of hepatology 41 (4), 599-605, 2004 | 79 | 2004 |
| Human hepatic Hepa RG cells maintain an organotypic phenotype with high intrinsic CYP 450 activity/metabolism and significantly outperform standard HepG2/C3A cells for … LJ Nelson, K Morgan, P Treskes, K Samuel, CJ Henderson, C LeBled, ... Basic & clinical pharmacology & toxicology 120 (1), 30-37, 2017 | 69 | 2017 |
| Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery Journal of British Surgery 107 (2), e161-e169, 2020 | 61 | 2020 |
| Mitogen-activated protein kinases (MAPKs) and cholangiocarcinoma: the missing link C Chen, LJ Nelson, MA Ávila, FJ Cubero Cells 8 (10), 1172, 2019 | 58 | 2019 |
| Next-generation sequencing of bile cell-free DNA for the early detection of patients with malignant biliary strictures M Arechederra, M Rullán, I Amat, D Oyon, L Zabalza, M Elizalde, ... Gut 71 (6), 1141-1151, 2022 | 56 | 2022 |
| Acetaminophen cytotoxicity is ameliorated in a human liver organotypic co-culture model LJ Nelson, M Navarro, P Treskes, K Samuel, O Tura-Ceide, SD Morley, ... Scientific reports 5 (1), 17455, 2015 | 56 | 2015 |
| Low-shear modelled microgravity environment maintains morphology and differentiated functionality of primary porcine hepatocyte cultures LJ Nelson, SW Walker, PC Hayes, JN Plevris Cells Tissues Organs 192 (2), 125-140, 2010 | 55 | 2010 |
| Low-dose acetaminophen induces early disruption of cell-cell tight junctions in human hepatic cells and mouse liver W Gamal, P Treskes, K Samuel, GJ Sullivan, R Siller, V Srsen, K Morgan, ... Scientific reports 7 (1), 37541, 2017 | 52 | 2017 |
| The simulated microgravity environment maintains key metabolic functions and promotes aggregation of primary porcine hepatocytes KJ Dabos, LJ Nelson, TJ Bradnock, JA Parkinson, IH Sadler, PC Hayes, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1526 (2), 119-130, 2001 | 51 | 2001 |
| Dual targeting of G9a and DNA methyltransferase‐1 for the treatment of experimental cholangiocarcinoma L Colyn, M Bárcena‐Varela, G Álvarez‐Sola, MU Latasa, I Uriarte, ... Hepatology 73 (6), 2380-2396, 2021 | 46 | 2021 |
| Fibrotic events in the progression of cholestatic liver disease H Wu, C Chen, S Ziani, LJ Nelson, MA Ávila, YA Nevzorova, FJ Cubero Cells 10 (5), 1107, 2021 | 45 | 2021 |
| Development of an invasively monitored porcine model of acetaminophen-induced acute liver failure PN Newsome, NC Henderson, LJ Nelson, C Dabos, C Filippi, C Bellamy, ... BMC gastroenterology 10, 1-13, 2010 | 43 | 2010 |
| The calcium‐binding domain of the stress protein SEP53 is required for survival in response to deoxycholic acid‐mediated injury J Darragh, M Hunter, E Pohler, L Nelson, JF Dillon, R Nenutil, B Vojtesek, ... The FEBS journal 273 (9), 1930-1947, 2006 | 39 | 2006 |
| Chlorpromazine toxicity is associated with disruption of cell membrane integrity and initiation of a pro-inflammatory response in the HepaRG hepatic cell line K Morgan, N Martucci, A Kozlowska, W Gamal, F Brzeszczyński, ... Biomedicine & Pharmacotherapy 111, 1408-1416, 2019 | 38 | 2019 |
John N PlevrisProfessor / Consultant, Centre for Liver & Digestive Disorders, Hepatology Lab, UEdinburghVerified email at ed.ac.uk
