| Lysosomal storage disorders – challenges, concepts and avenues for therapy: beyond rare diseases ARA Marques, P Saftig Journcal of Cell Science 132 (2), jcs221739, 2019 | 225 | 2019 |
| Novel activity-based probes for broad-spectrum profiling of retaining β-exoglucosidases in situ and in vivo WW Kallemeijn, KY Li, MD Witte, ARA Marques, J Aten, S Scheij, J Jiang, ... Angewandte Chemie International Edition 51 (50), 12529-12533, 2012 | 168 | 2012 |
| Lysosomal glycosphingolipid catabolism by acid ceramidase: formation of glycosphingoid bases during deficiency of glycosidases MJ Ferraz, ARA Marques, MD Appelman, M Verhoek, A Strijland, ... FEBS letters 590 (6), 716-725, 2016 | 159 | 2016 |
| Gaucher disease and Fabry disease: new markers and insights in pathophysiology for two distinct glycosphingolipidoses MJ Ferraz, WW Kallemeijn, M Mirzaian, DH Moro, A Marques, P Wisse, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2014 | 137 | 2014 |
| Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis ARA Marques, A Di Spiezio, N Thießen, L Schmidt, J Grötzinger, ... Autophagy 16 (5), 811-825, 2020 | 108 | 2020 |
| Glucosylated cholesterol in mammalian cells and tissues: Formation and degradation by multiple cellular β-glucosidases [S] ARA Marques, M Mirzaian, H Akiyama, P Wisse, MJ Ferraz, P Gaspar, ... Journal of lipid research 57 (3), 451-463, 2016 | 104 | 2016 |
| Current methods to analyze lysosome morphology, positioning, motility and function DC Barral, L Staiano, C Guimas Almeida, DF Cutler, ER Eden, CE Futter, ... Traffic 23 (5), 238-269, 2022 | 93 | 2022 |
| Reducing GBA2 activity ameliorates neuropathology in Niemann-Pick type C mice ARA Marques, J Aten, R Ottenhoff, CPAA van Roomen, D Herrera Moro, ... PloS one 10 (8), e0135889, 2015 | 86 | 2015 |
| Lentiviral gene therapy using cellular promoters cures type 1 Gaucher disease in mice M Dahl, A Doyle, K Olsson, JE Månsson, ARA Marques, M Mirzaian, ... Molecular Therapy 23 (5), 835-844, 2015 | 81 | 2015 |
| The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation V Sorrentino, JK Nelson, E Maspero, ARA Marques, L Scheer, S Polo, ... Journal of lipid research 54 (8), 2174-2184, 2013 | 74 | 2013 |
| Cell senescence, multiple organelle dysfunction and atherosclerosis G Machado-Oliveira, C Ramos, ARA Marques, OV Vieira Cells 9 (10), 2146, 2020 | 68 | 2020 |
| Lyso-glycosphingolipid abnormalities in different murine models of lysosomal storage disorders MJ Ferraz, ARA Marques, P Gaspar, M Mirzaian, C van Roomen, ... Molecular genetics and metabolism 117 (2), 186-193, 2016 | 56 | 2016 |
| Gpnmb is a potential marker for the visceral pathology in Niemann-Pick type C disease ARA Marques, TL Gabriel, J Aten, CPAA van Roomen, R Ottenhoff, ... PLoS One 11 (1), e0147208, 2016 | 55 | 2016 |
| Simultaneous quantitation of sphingoid bases by UPLC-ESI-MS/MS with identical 13C-encoded internal standards M Mirzaian, P Wisse, MJ Ferraz, ARA Marques, P Gaspar, SV Oussoren, ... Clinica Chimica Acta 466, 178-184, 2017 | 51 | 2017 |
| Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models S Prieto Huarcaya, A Drobny, ARA Marques, A Di Spiezio, JP Dobert, ... Autophagy 18 (5), 1127-1151, 2022 | 45 | 2022 |
| Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes D Herrera Moro Chao, WW Kallemeijn, ARA Marques, M Orre, R Ottenhoff, ... PLoS One 10 (9), e0138107, 2015 | 44 | 2015 |
| Lysosome (Dys) function in atherosclerosis—a big weight on the shoulders of a small organelle ARA Marques, C Ramos, G Machado-Oliveira, OV Vieira Frontiers in cell and developmental biology 9, 658995, 2021 | 32 | 2021 |
| A specific activity‐based probe to monitor family GH59 galactosylceramidase, the enzyme deficient in Krabbe disease ARA Marques, LI Willems, D Herrera Moro, BI Florea, S Scheij, ... ChemBioChem 18 (4), 402-412, 2017 | 28 | 2017 |
| Cathepsin D: Analysis of its potential role as an amyloid beta degrading protease L Gallwitz, L Schmidt, ARA Marques, A Tholey, L Cassidy, I Ulku, ... Neurobiology of Disease 175, 105919, 2022 | 23 | 2022 |
| Accurate quantification of sphingosine-1-phosphate in normal and Fabry disease plasma, cells and tissues by LC-MS/MS with 13C-encoded natural S1P as internal standard M Mirzaian, P Wisse, MJ Ferraz, ARA Marques, TL Gabriel, ... Clinica chimica acta 459, 36-44, 2016 | 23 | 2016 |
H.S. OverkleeftProfessor of Bio-organic Synthesis, Leiden UniversityVerified email at lic.leidenuniv.nl