| Organ aging signatures in the plasma proteome track health and disease HSH Oh, J Rutledge, D Nachun, R Pálovics, O Abiose, P Moran-Losada, ... Nature 624 (7990), 164-172, 2023 | 189 | 2023 |
| Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer’s disease H Holstege, M Hulsman, C Charbonnier, B Grenier-Boley, O Quenez, ... Nature genetics 54 (12), 1786-1794, 2022 | 159* | 2022 |
| Association of Klotho-VS heterozygosity with risk of Alzheimer disease in individuals who carry APOE4 ME Belloy, V Napolioni, SS Han, Y Le Guen, MD Greicius, ... JAMA neurology 77 (7), 849-862, 2020 | 103 | 2020 |
| APOE genotype and Alzheimer disease risk across age, sex, and population ancestry ME Belloy, SJ Andrews, Y Le Guen, M Cuccaro, LA Farrer, V Napolioni, ... JAMA neurology 80 (12), 1284-1294, 2023 | 80 | 2023 |
| Genetic influence on the sulcal pits: on the origin of the first cortical folds Y Le Guen, G Auzias, F Leroy, M Noulhiane, G Dehaene-Lambertz, ... Cerebral Cortex 28 (6), 1922-1933, 2018 | 69 | 2018 |
| Association of rare APOE missense variants V236E and R251G with risk of Alzheimer disease Y Le Guen, ME Belloy, B Grenier-Boley, I De Rojas, A Castillo-Morales, ... JAMA neurology 79 (7), 652-663, 2022 | 64 | 2022 |
| PyPNS: Multiscale simulation of a peripheral nerve in python CH Lubba, Y Le Guen, S Jarvis, NS Jones, SC Cork, A Eftekhar, ... Neuroinformatics 17, 63-81, 2019 | 44 | 2019 |
| Common X‐chromosome variants are associated with Parkinson disease risk Y Le Guen, V Napolioni, ME Belloy, E Yu, L Krohn, JA Ruskey, Z Gan‐Or, ... Annals of neurology 90 (1), 22-34, 2021 | 43 | 2021 |
| “Plis de passage” deserve a role in models of the cortical folding process JF Mangin, Y Le Guen, N Labra, A Grigis, V Frouin, M Guevara, C Fischer, ... Brain Topography 32 (6), 1035-1048, 2019 | 40 | 2019 |
| Performance of a fully-automated Lumipulse plasma phospho-tau181 assay for Alzheimer’s disease EN Wilson, CB Young, J Ramos Benitez, MS Swarovski, I Feinstein, ... Alzheimer's Research & Therapy 14 (1), 172, 2022 | 37 | 2022 |
| Identification of putative causal loci in whole-genome sequencing data via knockoff statistics Z He, L Liu, C Wang, Y Le Guen, J Lee, S Gogarten, F Lu, S Montgomery, ... Nature communications 12 (1), 3152, 2021 | 35 | 2021 |
| Association of African Ancestry–Specific APOE Missense Variant R145C With Risk of Alzheimer Disease Y Le Guen, AC Raulin, MW Logue, R Sherva, ME Belloy, SJ Eger, A Chen, ... JAMA 329 (7), 551-560, 2023 | 33 | 2023 |
| The chaotic morphology of the left superior temporal sulcus is genetically constrained Y Le Guen, F Leroy, G Auzias, D Riviere, A Grigis, JF Mangin, O Coulon, ... NeuroImage 174, 297-307, 2018 | 31 | 2018 |
| Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and informs causal proteins for Alzheimer’s disease C Cruchaga, D Western, J Timsina, L Wang, C Wang, C Yang, M Ali, ... Research square, 2023 | 29 | 2023 |
| Multiancestry analysis of the HLA locus in Alzheimer’s and Parkinson’s diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes Y Le Guen, G Luo, A Ambati, V Damotte, I Jansen, E Yu, A Nicolas, ... Proceedings of the National Academy of Sciences 120 (36), e2302720120, 2023 | 28* | 2023 |
| eQTL of KCNK2 regionally influences the brain sulcal widening: evidence from 15,597 UK Biobank participants with neuroimaging data Y Le Guen, C Philippe, D Riviere, H Lemaitre, A Grigis, C Fischer, ... Brain Structure and Function 224 (2), 847-857, 2019 | 27 | 2019 |
| A novel age-informed approach for genetic association analysis in Alzheimer’s disease Y Le Guen, ME Belloy, V Napolioni, SJ Eger, G Kennedy, R Tao, Z He, ... Alzheimer's Research & Therapy 13, 1-14, 2021 | 26 | 2021 |
| Shared genetic aetiology between cognitive performance and brain activations in language and math tasks Y Le Guen, M Amalric, P Pinel, C Pallier, V Frouin Scientific Reports 8 (1), 17624, 2018 | 25 | 2018 |
| Genome-wide analysis of common and rare variants via multiple knockoffs at biobank scale, with an application to Alzheimer disease genetics Z He, Y Le Guen, L Liu, J Lee, S Ma, AC Yang, X Liu, J Rutledge, ... The American Journal of Human Genetics 108 (12), 2336-2353, 2021 | 23 | 2021 |
| Enhancer locus in ch14q23. 1 modulates brain asymmetric temporal regions involved in language processing Y Le Guen, F Leroy, C Philippe, Imagen Consortium, JF Mangin, ... Cerebral Cortex 30 (10), 5322-5332, 2020 | 20 | 2020 |